Q63J95 (Q63J95_BURPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptidyl-prolyl cis-trans isomerase RuleBase RU004231
EC=5.2.1.8 RuleBase RU003915

Gene names

Name:	fbp EMBL CAH39299.1
Ordered Locus Names:	BPSS1823

Organism

Burkholderia pseudomallei (strain K96243) [Reference proteome] [HAMAP]

Taxonomic identifier

272560 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group › Burkholderia pseudomallei

Protein attributes

Sequence length	113 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Peptidylproline (omega=180) = peptidylproline (omega=0). RuleBase RU003915
Sequence similarities	Contains 1 PPIase FKBP-type domain. RuleBase RU004231

Ontologies

Keywords
Molecular function	Isomerase Rotamase RuleBase RU003715
Technical term	3D-structure PDB 2KE0 PDB 2KO7 PDB 3UQA PDB 2Y78 Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: UniProtKB-KW protein peptidyl-prolyl isomerization Inferred from electronic annotation. Source: GOC
Molecular_function	peptidyl-prolyl cis-trans isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q63J95 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 10AB26FB56F3F284	FASTA	113	11,930
	10 20 30 40 50 60 MTVVTTESGL KYEDLTEGSG AEARAGQTVS VHYTGWLTDG QKFDSSKDRN DPFAFVLGGG 70 80 90 100 110 MVIKGWDEGV QGMKVGGVRR LTIPPQLGYG ARGAGGVIPP NATLVFEVEL LDV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei." Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M., Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F., Challis G.L. , Cherevach I., Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K96243.
[2]	"The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development." Norville I.H., O'Shea K., Sarkar-Tyson M., Zheng S., Titball R.W., Varani G., Harmer N.J. Biochem. J. 437:413-422(2011) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY NMR.
[3]	"Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation A54E from Burkholderia pseudomallei complexed with FK506." Seattle Structural Genomics Center for Infectious Disease (SSGCID) Fox III D., Abendroth J., Staker B., Stewart L. Submitted (NOV-2011) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 2-113.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

BX571966 Genomic DNA. Translation: CAH39299.1.

RefSeq

YP_111827.1. NC_006351.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2KE0	NMR	-	A	1-113	[»]
2KO7	NMR	-	A	1-113	[»]
2Y78	X-ray	0.91	A	1-113	[»]
3UQA	X-ray	1.55	A	2-113	[»]

ProteinModelPortal

Q63J95.

ModBase

Search...

Protein-protein interaction databases

STRING

272560.BPSS1823.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

3094935.

KEGG

bps:BPSS1823.

PATRIC

19271960. VBIBurPse99623_6150.

Phylogenomic databases

HOGENOM

HOG000154887.

KO

K01802.

OMA

PFEFPIG.

ProtClustDB

CLSK931378.

Enzyme and pathway databases

BioCyc

BPSE272560:GJNI-5397-MONOMER.

Family and domain databases

InterPro

IPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view]

PANTHER

PTHR10516. PTHR10516. 1 hit.

Pfam

PF00254. FKBP_C. 1 hit.
[Graphical view]

PROSITE

PS50059. FKBP_PPIASE. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q63J95.

Entry information

Entry name

Q63J95_BURPS

Accession

Primary (citable) accession number: Q63J95

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2004
Last sequence update:	October 25, 2004
Last modified:	May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)