Reviewed, UniProtKB/Swiss-Prot Q63IA7 (ACYP_BURPS)

Names and origin

Protein names

Recommended name:
    Acylphosphatase
    EC=3.6.1.7
Alternative name(s):
    Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	BPSS2164

Organism

Burkholderia pseudomallei (Pseudomonas pseudomallei) [Complete proteome] [HAMAP]

Taxonomic identifier

28450 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	98 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 98	98	Acylphosphatase HAMAP MF_01450		PRO_0000326672
Regions
	Domain	12 – 98	87	Acylphosphatase-like
Sites
	Active site	27	1	By similarity
	Active site	45	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q63IA7-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: D5B03E686EBC2B79	FASTA	98	11,254
	10 20 30 40 50 60 MSGDDLDERI ETYYVRVRGV VQGVGFRHAT VREAHALKLR GWVANLDDGS VEAMLQGSAP 70 80 90 QIDRMLAWLR HGPPAAHVTE VTFEEHRTDK RFERFQQH

References

[1]

"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei." Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M., Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F., Challis G.L. , Cherevach I., Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J. Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004) [PubMed: 15377794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K96243.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX571966 Genomic DNA. Translation: CAH39648.1.
RefSeq	YP_112165.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3095820.
GenomeReviews	Gene locus BPSS2164 in contig BX571966_GR.
KEGG	bps:BPSS2164.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q63IA7.
OMA	AMLQGPA.
Enzyme and pathway databases
BioCyc	BPSE272560:BPSS2164-MON.
BRENDA	3.6.1.7. 275934.
Family and domain databases
HAMAP	MF_01450. [Tree]
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
PANTHER	PTHR10029. Acylphosphatase. 1 hit.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
ProDom	PD001884. Acylphosphatase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_BURPS

Accession

Primary (citable) accession number: Q63IA7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	October 25, 2004
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)