Reviewed, UniProtKB/Swiss-Prot Q639Y8 (MQO_BACCZ)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	BCE33L2692

Organism

Bacillus cereus (strain ZK / E33L) [Complete proteome] [HAMAP]

Taxonomic identifier

288681 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000023792

Sequences

	Sequence		Length	Mass (Da)
	Q639Y8-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: C72C306F8B5DEB6F	FASTA	500	55,180
	10 20 30 40 50 60 MSNMQQKTDV ILIGAGIMSA TLGSLLKELA PEWEIKVFEK LASAGEESSN EWNNAGTGHS 70 80 90 100 110 120 ALCELNYTSE KSDGSIDISK AVKVNEQFQL SRQFWAYLVK SKLIRNPQDF IMPLPHMSLV 130 140 150 160 170 180 QGEKNVEFLK NRFEALSKNP LFQGMEFSDA PETLKKWLPL IMEGRTSNEP MAATKIDSGT 190 200 210 220 230 240 DVNFGALTRM LFNYLKTKDV ELNYKHSVEN IKRTKNGLWE VKVHDMNSGK IEHHTAKFVF 250 260 270 280 290 300 IGGGGGSLPL LQKTGIPESK HIGGFPVSGL FMVCKNQKVV EQHHAKVYGK AKVGAPPMSV 310 320 330 340 350 360 PHLDTRYIDN KKALLFGPFA GFSPKFLKTG SNLDLIGSVK PNNVLTMLAA GVKEMGLTKY 370 380 390 400 410 420 LIQQVMLSHE KRMEELREFI PNAKSEDWDI VVAGQRVQVI KDTDAGGKGT LQFGTEVVSA 430 440 450 460 470 480 ADGSIAALLG ASPGASTAVH VMLEVLEKCF PSRMVEWEGK IKEMIPSYGI SLTENPRLFQ 490 500 DLHTSTGRTL GLNEKETVHN

References

[1]

"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis." Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P. , Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P. J. Bacteriol. 188:3382-3390(2006) [PubMed: 16621833] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000001 Genomic DNA. Translation: AAU17569.1.
RefSeq	YP_084279.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q639Y8.
Genome annotation databases
GeneID	3025524.
GenomeReviews	Gene locus BCE33L2692 in contig CP000001_GR.
KEGG	bcz:BCZK2692.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	NTQFEVS.
Enzyme and pathway databases
BioCyc	BCER288681:BCE33L2692-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_BACCZ

Accession

Primary (citable) accession number: Q639Y8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2004
Last modified:	February 9, 2010
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)