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Protein
Submitted name:

Alpha globin

Gene

Hba-a3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi59Iron (heme distal ligand)PROSITE-ProRule annotation1
Metal bindingi88Iron (heme proximal ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

  • heme binding Source: RGD
  • iron ion binding Source: InterPro
  • organic acid binding Source: RGD
  • oxygen binding Source: InterPro
  • oxygen carrier activity Source: UniProtKB-KW

GO - Biological processi

  • protein heterooligomerization Source: RGD

Keywordsi

Biological processOxygen transportPROSITE-ProRule annotationSAAS annotation, Transport
LigandHemePROSITE-ProRule annotationSAAS annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha globinImported
Submitted name:
Globin c1Imported
Submitted name:
Hemoglobin alpha, adult chain 3Imported
Submitted name:
RCG33691Imported
Gene namesi
Name:Hba-a3Imported
Synonyms:Glnc1Imported, GloAImported, Hba-a1Imported, LOC287167Imported
ORF Names:rCG_33691Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1359209 Hba-a3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ63910

Expressioni

Gene expression databases

BgeeiENSRNOG00000045989

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000041451

Structurei

3D structure databases

SMRiQ63910
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 142GLOBINInterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3378 Eukaryota
COG1018 LUCA
GeneTreeiENSGT00760000119197
HOGENOMiHOG000036867
HOVERGENiHBG009709
KOiK13822
OMAiVFAIKFP
OrthoDBiEOG091G0S0X
TreeFamiTF332328

Family and domain databases

CDDicd08927 Hb-alpha_like, 1 hit
Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002338 Haemoglobin_a-typ
IPR002339 Haemoglobin_pi
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00612 ALPHAHAEM
PR00815 PIHAEM
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q63910-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLSEEDKNN IKKAWVKIGN HAAEIGAETI GRLFIVFPSS KTYFPHFNTS
60 70 80 90 100
EGSDQVKAHG KKVADALTNA ASHLDDLPGA LSTLSDLHAH KLRVDPVNFK
110 120 130 140
FLSHCLLVTL ASHHPGDFTP AMHASLDKFF ASVSTVLTSK YR
Length:142
Mass (Da):15,525
Last modified:January 1, 1998 - v2
Checksum:i92B3CA50D9CD8619
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096051 Genomic DNA No translation available.
U62315 Genomic DNA Translation: AAB40623.1
CH473948 Genomic DNA Translation: EDM04007.1
LT548168 Genomic DNA Translation: SAI82215.1
PIRiI68530
RefSeqiNP_001013875.1, NM_001013853.1
UniGeneiRn.163132

Genome annotation databases

EnsembliENSRNOT00000052292; ENSRNOP00000041451; ENSRNOG00000045989
GeneIDi287167
KEGGirno:287167
UCSCiRGD:1359209 rat

Similar proteinsi

Entry informationi

Entry nameiQ63910_RAT
AccessioniPrimary (citable) accession number: Q63910
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 141 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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