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Q63870

- CO7A1_MOUSE

UniProt

Q63870 - CO7A1_MOUSE

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Protein

Collagen alpha-1(VII) chain

Gene

Col7a1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.By similarity1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei2889 – 28902Reactive bondBy similarity

GO - Molecular functioni

  1. identical protein binding Source: IntAct
  2. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW

GO - Biological processi

  1. cell adhesion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Keywords - Biological processi

Cell adhesion

Enzyme and pathway databases

ReactomeiREACT_196595. Anchoring fibril formation.
REACT_198984. Collagen biosynthesis and modifying enzymes.
REACT_199055. Collagen degradation.
REACT_202342. Laminin interactions.
REACT_206066. Extracellular matrix organization.
REACT_216309. Integrin cell surface interactions.

Protein family/group databases

MEROPSiI02.967.

Names & Taxonomyi

Protein namesi
Recommended name:
Collagen alpha-1(VII) chain
Alternative name(s):
Long-chain collagen
Short name:
LC collagen
Gene namesi
Name:Col7a1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:88462. Col7a1.

Subcellular locationi

GO - Cellular componenti

  1. basement membrane Source: MGI
  2. collagen trimer Source: UniProtKB-KW
  3. extracellular region Source: Reactome
  4. extracellular space Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Basement membrane, Extracellular matrix, Secreted

Pathology & Biotechi

Disruption phenotypei

Mice do not express type VII collagen in their skin; they are born with extensive cutaneous blistering and die during the first two weeks of life, possibly because of complications arising from blistering; this mouse mutant resembles the autosomal recessive inherited form of the dystrophic epidermolysis bullosa (DEB) in humans. Heterozygotes by comparison display a normal phenotype.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence AnalysisAdd
BLAST
Chaini25 – 29442920Collagen alpha-1(VII) chainSequence AnalysisPRO_0000282951Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi338 – 3381N-linked (GlcNAc...)Sequence Analysis
Glycosylationi787 – 7871N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1110 – 11101N-linked (GlcNAc...)Sequence Analysis
Modified residuei2158 – 215814-hydroxyprolineBy similarity
Modified residuei2167 – 216714-hydroxyprolineBy similarity
Modified residuei2176 – 217614-hydroxyprolineBy similarity
Modified residuei2179 – 217914-hydroxyprolineBy similarity
Modified residuei2616 – 261615-hydroxylysineBy similarity
Modified residuei2622 – 262215-hydroxylysineBy similarity
Disulfide bondi2625 – 2625InterchainPROSITE-ProRule annotation
Modified residuei2655 – 265514-hydroxyprolineBy similarity
Modified residuei2658 – 265814-hydroxyprolineBy similarity
Modified residuei2664 – 266414-hydroxyprolineBy similarity
Disulfide bondi2793 – 2793InterchainPROSITE-ProRule annotation
Disulfide bondi2795 – 2795InterchainPROSITE-ProRule annotation
Disulfide bondi2879 ↔ 2931PROSITE-ProRule annotation
Disulfide bondi2888 ↔ 2914PROSITE-ProRule annotation
Disulfide bondi2906 ↔ 2927PROSITE-ProRule annotation

Post-translational modificationi

Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.Curated

Keywords - PTMi

Disulfide bond, Glycoprotein, Hydroxylation

Proteomic databases

PaxDbiQ63870.
PRIDEiQ63870.

PTM databases

PhosphoSiteiQ63870.

Expressioni

Inductioni

Transcription of COL7A1 is stimulated by TGFB1 in keratinocytes and this is possibly dependent on a putative interaction between SMADS and AP1.1 Publication

Gene expression databases

BgeeiQ63870.
CleanExiMM_COL7A1.
GenevestigatoriQ63870.

Interactioni

Subunit structurei

Homotrimer. Interacts with MIA3/TANGO1; facilitating its loading into transport carriers and subsequent secretion (By similarity).By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-8313134,EBI-8313134

Protein-protein interaction databases

IntActiQ63870. 1 interaction.
MINTiMINT-4109970.

Structurei

3D structure databases

ProteinModelPortaliQ63870.
SMRiQ63870. Positions 39-216, 231-1205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 212174VWFA 1PROSITE-ProRule annotationAdd
BLAST
Domaini235 – 33096Fibronectin type-III 1PROSITE-ProRule annotationAdd
BLAST
Domaini331 – 41787Fibronectin type-III 2PROSITE-ProRule annotationAdd
BLAST
Domaini418 – 50891Fibronectin type-III 3PROSITE-ProRule annotationAdd
BLAST
Domaini511 – 59888Fibronectin type-III 4PROSITE-ProRule annotationAdd
BLAST
Domaini601 – 68888Fibronectin type-III 5PROSITE-ProRule annotationAdd
BLAST
Domaini689 – 77688Fibronectin type-III 6PROSITE-ProRule annotationAdd
BLAST
Domaini779 – 86789Fibronectin type-III 7PROSITE-ProRule annotationAdd
BLAST
Domaini870 – 95788Fibronectin type-III 8PROSITE-ProRule annotationAdd
BLAST
Domaini959 – 105395Fibronectin type-III 9PROSITE-ProRule annotationAdd
BLAST
Domaini1055 – 1230176VWFA 2PROSITE-ProRule annotationAdd
BLAST
Domaini2879 – 293153BPTI/Kunitz inhibitorPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni18 – 12541237Nonhelical region (NC1)Sequence AnalysisAdd
BLAST
Regioni1255 – 27751521Triple-helical regionSequence AnalysisAdd
BLAST
Regioni1255 – 1475221Interrupted collagenous regionSequence AnalysisAdd
BLAST
Regioni2776 – 2944169Nonhelical region (NC2)Sequence AnalysisAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi1171 – 11733Cell attachment siteSequence Analysis
Motifi2002 – 20043Cell attachment siteSequence Analysis
Motifi2063 – 20653Cell attachment siteSequence Analysis
Motifi2601 – 26033Cell attachment siteSequence Analysis
Motifi2631 – 26333Cell attachment siteSequence Analysis

Sequence similaritiesi

Contains 1 BPTI/Kunitz inhibitor domain.PROSITE-ProRule annotation
Contains 9 fibronectin type-III domains.PROSITE-ProRule annotation
Contains 2 VWFA domains.PROSITE-ProRule annotation

Keywords - Domaini

Collagen, Repeat, Signal

Phylogenomic databases

eggNOGiNOG12793.
GeneTreeiENSGT00760000118776.
HOGENOMiHOG000111866.
HOVERGENiHBG051053.
InParanoidiQ63870.
KOiK16628.
OMAiWHSGHGP.
OrthoDBiEOG7CG6Z4.
PhylomeDBiQ63870.
TreeFamiTF351645.

Family and domain databases

Gene3Di2.60.40.10. 9 hits.
3.40.50.410. 2 hits.
4.10.410.10. 1 hit.
InterProiIPR008160. Collagen.
IPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR002223. Prot_inh_Kunz-m.
IPR020901. Prtase_inh_Kunz-CS.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01391. Collagen. 22 hits.
PF00041. fn3. 9 hits.
PF00014. Kunitz_BPTI. 1 hit.
PF00092. VWA. 2 hits.
[Graphical view]
PRINTSiPR00759. BASICPTASE.
SMARTiSM00060. FN3. 9 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 5 hits.
SSF53300. SSF53300. 2 hits.
SSF57362. SSF57362. 1 hit.
PROSITEiPS00280. BPTI_KUNITZ_1. 1 hit.
PS50279. BPTI_KUNITZ_2. 1 hit.
PS50853. FN3. 9 hits.
PS50234. VWFA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q63870-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLRLLVAAL CAAEILMGAP EVWAQPRDRV TCTRLYAADI VFLLDGSSSI
60 70 80 90 100
GRSNFREVRG FLEGLVLPFS GAASAQGVRF ATVQYSDDPQ TEFGLDTLGS
110 120 130 140 150
GSDTIRAIRE LSYKGGNTRT GAALHHVSDR VFLPRLTRPG VPKVCILITD
160 170 180 190 200
GKSQDLVDTA AQKLKGQGVK LFAVGIKNAD PEELKRVASQ PTSDFFFFVN
210 220 230 240 250
DFSILRTLLP LISRRVCTTA GGVPVTLPSD DTPSGPRDLV LSEPSSQSLR
260 270 280 290 300
VQWTAASGPV TGYKVQYTPL TGLGQPLPSE RQEVNIPAGE TSTRLQGLRP
310 320 330 340 350
LTDYQVTVVA LYANSIGEAV SGTARTTAKE GLELSLQNIT SHSLLVAWRR
360 370 380 390 400
VPGANGYRVT WRDLSGGPTQ QQDLSPGQGS VFLDHLEPGT DYEVTVSALF
410 420 430 440 450
GHSVGPAASL TARTASSVEQ TLHPIILSPT SILLSWNLVP EARGYRLEWR
460 470 480 490 500
RESGLETPQK VELPPDVTRH QLDGLQPGTE YRLTLYTLLE GREVATPATV
510 520 530 540 550
VPTGLEQLVS PVMNLQAIEL PGQRVRVSWN PVPGATEYRF TVRTTQGVER
560 570 580 590 600
TLLLPGSQTT FDLDDVRAGL SYTVRVSARV GAQEGDASIL TIHRDPEAPL
610 620 630 640 650
VVPGLRVVAS DATRIRVAWG LVPGASGFRI SWRTGSGPES SRTLTPDSTV
660 670 680 690 700
TDILGLQPST SYQVAVSALR GREEGPPVVI VARTDPLGPV RRVHLTQAGS
710 720 730 740 750
SSVSITWTGV PGATGYRVSW HSGHGPEKSL LVSGDATVAE IDGLEPDTEY
760 770 780 790 800
IVRVRTHVAG VDGAPASVVV RTAPEPVGSV SKLQILNASS DVLRVTWVGV
810 820 830 840 850
PGATSYKLAW GRSEGGPMKH RILPGNKESA EIRDLEGGVS YSVRVTALVG
860 870 880 890 900
DREGAPVSIV ITTPPATPAL LETLQVVQSG EHSLRLRWEP VPGAPGFRLH
910 920 930 940 950
WQPEGGQEQS LTLGPESNSY NLVGLEPATK YQVWLTVLGQ TGEGPPRKVT
960 970 980 990 1000
AYTEPSHIPS TELRVVDTSI DSVTLTWTPV SGASSYILSW RPLRGTGQEV
1010 1020 1030 1040 1050
PRAPQTLPGT SSSHRVTGLE PGISYVFSLT PIQSGVRGSE ISVTQTPACS
1060 1070 1080 1090 1100
HGPVDVVFLL HATRDNAHNA EAVRRVLERL VSALGPLGPQ AAQVGLLTYS
1110 1120 1130 1140 1150
HRPSPLFPLN SSHDLGIILR KIRDIPYVDP SGNNLGTAVT TAHRYLLASN
1160 1170 1180 1190 1200
APGRRQQVPG VMVLLVDEPL RGDILSPIRE AQTSGLKVMA LSLVGADPEQ
1210 1220 1230 1240 1250
LRRLAPGTDP IQNFFAVDNG PGLDRAVSDL AVALCQAAVT IEPQTGPCAV
1260 1270 1280 1290 1300
HCPKGQKGEP GVTGLQGQAG PPGPPGLPGR TGAPGPQGPP GSTQAKGERG
1310 1320 1330 1340 1350
FPGPEGPPGS PGLPGVPGSP GIKGSTGRPG PRGEQGERGP QGPKGEPGEP
1360 1370 1380 1390 1400
GQITGGGGPG FPGKKGDPGP SGPPGSRGPV GDPGPRGPPG LPGISVKGDK
1410 1420 1430 1440 1450
GDRGERGPPG PGIGASEQGD PGLPGLPGSP GPQGPAGRPG EKGEKGDCED
1460 1470 1480 1490 1500
GGPGLPGQPG PPGEPGLRGA PGMTGPKGDR GLTGTPGEPG VKGERGHPGP
1510 1520 1530 1540 1550
VGPQGLPGAA GHPGVEGPEG PPGPTGRRGE KGEPGRPGDP AVGPGGAGAK
1560 1570 1580 1590 1600
GEKGEAGLPG PRGASGSKGE QGAPGLALPG DPGPKGDPGD RGPIGLTGRA
1610 1620 1630 1640 1650
GPTGDSGPPG EKGEPGRPGS PGPVGPRGRD GEAGEKGDEG IPGEPGLPGK
1660 1670 1680 1690 1700
AGERGLRGAP GPRGPVGEKG DQGDPGEDGR NGSPGSSGPK GDRGEPGPPG
1710 1720 1730 1740 1750
PPGRLVDAGI ESRDKGEPGQ EGPRGPKGDP GPPGVSGERG IDGLRGPPGP
1760 1770 1780 1790 1800
QGDPGVRGPA GDKGDRGPPG LDGRSGLDGK PGAPGPPGLH GASGKAGDPG
1810 1820 1830 1840 1850
RDGLPGLRGE HGPPGPPGPP GVPGKAGDDG KPGLNGKNGD PGDPGEDGRK
1860 1870 1880 1890 1900
GEKGDSGAPG REGPDGPKGE RGAPGNPGLQ GPPGLPGQVG PPGQGFPGVP
1910 1920 1930 1940 1950
GITGPKGDRG ETGSKGEQGL PGERGLRGEP GSLPNAERLL ETAGIKVSAL
1960 1970 1980 1990 2000
REIVDTWDES SGSFLPVPER RPGPKGDPGD RGPPGKEGLI GFPGERGLKG
2010 2020 2030 2040 2050
ERGDPGPQGP PGLALGERGP PGPPGLAGEP GKPGIPGLPG RAGGSGEAGR
2060 2070 2080 2090 2100
PGERGERGEK GERGDQGRDG LPGLPGPPGP PGPKVAIEEP GPGLAREQGP
2110 2120 2130 2140 2150
PGLKGAKGEP GSDGDPGPKG DRGVPGIKGD VGEPGKRGHD GNPGLPGERG
2160 2170 2180 2190 2200
VAGPEGKPGL QGPRGTPGPV GSHGDPGPPG APGLAGPAGP QGPSGLKGEP
2210 2220 2230 2240 2250
GETGPPGRGL PGPVGAVGLP GPPGPSGLVG PQGSPGLPGQ VGETGKPGPP
2260 2270 2280 2290 2300
GRDGSSGKDG DRGSPGVPGS PGLPGPVGPK GEPGPVGAPG QVVVGPPGAK
2310 2320 2330 2340 2350
GEKGAPGDLA GALLGEPGAK GDRGLPGPRG EKGEAGRAGG PGDPGEDGQK
2360 2370 2380 2390 2400
GAPGLKGLKG EPGIGVQGPP GPSGPPGMKG DLGPPGAPGA PGVVGFPGQT
2410 2420 2430 2440 2450
GPRGETGQPG PVGERGLAGP PGREGAPGPL GPPGPPGSAG APGASGLKGD
2460 2470 2480 2490 2500
KGDPGAGLPG PRGERGEPGV RGEDGHPGQE GPRGLVGPPG SRGEQGEKGA
2510 2520 2530 2540 2550
AGAAGLKGDK GDSAVIEGPP GPRGAKGDMG ERGPRGIDGD KGPRGESGNP
2560 2570 2580 2590 2600
GDKGSKGEPG DKGSAGSIGV RGLTGPKGEP GAAGIPGEPG APGKDGIPGF
2610 2620 2630 2640 2650
RGDKGDIGFM GPRGLKGEKG IKGTCGRDGE RGDKGEAGFP GRPGLAGKKG
2660 2670 2680 2690 2700
DMGEPGLPGQ SGAPGKEGLI GPKGDRGFDG QSGPKGDQGE KGERGPPGVG
2710 2720 2730 2740 2750
GFPGPRGNDG SSGPPGPPGG VGPKGPEGLQ GQKGERGPPG ESVVGAPGAP
2760 2770 2780 2790 2800
GTPGERGEQG RPGPAGPRGE KGEAALTEDD IRDFVRQEMS QHCACQGQFI
2810 2820 2830 2840 2850
ASGSRPLPGY AADTAGSQLH HVPVLRVSHV EEEGQVPPED DDDFSEYSVY
2860 2870 2880 2890 2900
SVEDYQEPEV PWDGEAEIKG WDQRGSDLCS LPLDEGSCTA YTLRWYHRAV
2910 2920 2930 2940
PGGTACHPFV YGGCGGNANR FGTREACERR CPPQGVHSQK TGAA
Length:2,944
Mass (Da):295,232
Last modified:April 3, 2007 - v3
Checksum:i13D01CA7ED36C958
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti659 – 6591S → G in AAB66593. (PubMed:8752674)Curated
Sequence conflicti1927 – 19271R → A in AAB66593. (PubMed:8752674)Curated
Sequence conflicti1927 – 19271R → A in AAB27492. (PubMed:8325648)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U32107 mRNA. Translation: AAB66593.1.
AC174646 Genomic DNA. No translation available.
S63654 mRNA. Translation: AAB27492.1.
CCDSiCCDS40770.1.
PIRiA45748.
RefSeqiNP_031764.2. NM_007738.3.
XP_006511998.1. XM_006511935.1.
UniGeneiMm.6200.

Genome annotation databases

EnsembliENSMUST00000026740; ENSMUSP00000026740; ENSMUSG00000025650.
ENSMUST00000112070; ENSMUSP00000107701; ENSMUSG00000025650.
GeneIDi12836.
KEGGimmu:12836.
UCSCiuc009rrh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U32107 mRNA. Translation: AAB66593.1 .
AC174646 Genomic DNA. No translation available.
S63654 mRNA. Translation: AAB27492.1 .
CCDSi CCDS40770.1.
PIRi A45748.
RefSeqi NP_031764.2. NM_007738.3.
XP_006511998.1. XM_006511935.1.
UniGenei Mm.6200.

3D structure databases

ProteinModelPortali Q63870.
SMRi Q63870. Positions 39-216, 231-1205.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q63870. 1 interaction.
MINTi MINT-4109970.

Protein family/group databases

MEROPSi I02.967.

PTM databases

PhosphoSitei Q63870.

Proteomic databases

PaxDbi Q63870.
PRIDEi Q63870.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000026740 ; ENSMUSP00000026740 ; ENSMUSG00000025650 .
ENSMUST00000112070 ; ENSMUSP00000107701 ; ENSMUSG00000025650 .
GeneIDi 12836.
KEGGi mmu:12836.
UCSCi uc009rrh.1. mouse.

Organism-specific databases

CTDi 1294.
MGIi MGI:88462. Col7a1.

Phylogenomic databases

eggNOGi NOG12793.
GeneTreei ENSGT00760000118776.
HOGENOMi HOG000111866.
HOVERGENi HBG051053.
InParanoidi Q63870.
KOi K16628.
OMAi WHSGHGP.
OrthoDBi EOG7CG6Z4.
PhylomeDBi Q63870.
TreeFami TF351645.

Enzyme and pathway databases

Reactomei REACT_196595. Anchoring fibril formation.
REACT_198984. Collagen biosynthesis and modifying enzymes.
REACT_199055. Collagen degradation.
REACT_202342. Laminin interactions.
REACT_206066. Extracellular matrix organization.
REACT_216309. Integrin cell surface interactions.

Miscellaneous databases

NextBioi 282356.
PROi Q63870.
SOURCEi Search...

Gene expression databases

Bgeei Q63870.
CleanExi MM_COL7A1.
Genevestigatori Q63870.

Family and domain databases

Gene3Di 2.60.40.10. 9 hits.
3.40.50.410. 2 hits.
4.10.410.10. 1 hit.
InterProi IPR008160. Collagen.
IPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR002223. Prot_inh_Kunz-m.
IPR020901. Prtase_inh_Kunz-CS.
IPR002035. VWF_A.
[Graphical view ]
Pfami PF01391. Collagen. 22 hits.
PF00041. fn3. 9 hits.
PF00014. Kunitz_BPTI. 1 hit.
PF00092. VWA. 2 hits.
[Graphical view ]
PRINTSi PR00759. BASICPTASE.
SMARTi SM00060. FN3. 9 hits.
SM00327. VWA. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 5 hits.
SSF53300. SSF53300. 2 hits.
SSF57362. SSF57362. 1 hit.
PROSITEi PS00280. BPTI_KUNITZ_1. 1 hit.
PS50279. BPTI_KUNITZ_2. 1 hit.
PS50853. FN3. 9 hits.
PS50234. VWFA. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of mouse type VII collagen reveals evolutionary conservation of functional protein domains and genomic organization."
    Kivirikko S., Li K., Christiano A.M., Uitto J.
    J. Invest. Dermatol. 106:1300-1306(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "cDNA cloning and chromosomal mapping of the mouse type VII collagen gene (Col7a1): evidence for rapid evolutionary divergence of the gene."
    Li K., Christiano A.M., Copeland N.G., Gilbert D.J., Chu M.-L., Jenkins N.A., Uitto J.
    Genomics 16:733-739(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1139-2058.
  4. "Targeted inactivation of the type VII collagen gene (Col7a1) in mice results in severe blistering phenotype: a model for recessive dystrophic epidermolysis bullosa."
    Heinonen S., Mannikko M., Klement J.F., Whitaker-Menezes D., Murphy G.F., Uitto J.
    J. Cell Sci. 112:3641-3648(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.
  5. "Transcriptional control of the mouse Col7a1 gene in keratinocytes: basal and transforming growth factor-beta regulated expression."
    Naso M., Uitto J., Klement J.F.
    J. Invest. Dermatol. 121:1469-1478(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.

Entry informationi

Entry nameiCO7A1_MOUSE
AccessioniPrimary (citable) accession number: Q63870
Secondary accession number(s): Q78EC6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: April 3, 2007
Last modified: October 29, 2014
This is version 106 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3