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Q636F5 (KGUA_BACCZ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Guanylate kinase

EC=2.7.4.8
Alternative name(s):
GMP kinase
Gene names
Name:gmk
Ordered Locus Names:BCE33L3630
OrganismBacillus cereus (strain ZK / E33L) [Complete proteome] [HAMAP]
Taxonomic identifier288681 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length205 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328

Catalytic activity

ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00328.

Sequence similarities

Belongs to the guanylate kinase family.

Contains 1 guanylate kinase-like domain.

Sequence caution

The sequence AAU16637.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpurine nucleotide metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

guanylate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 205205Guanylate kinase HAMAP-Rule MF_00328
PRO_0000170493

Regions

Domain6 – 185180Guanylate kinase-like
Nucleotide binding13 – 208ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q636F5 [UniParc].

Last modified March 15, 2005. Version 2.
Checksum: BF987D07E1D8E531

FASTA20523,677
        10         20         30         40         50         60 
MRSRRGLLIV LSGPSGVGKG TVRKELFSHE DTRFQYSISV TTRKPREGEV DGVDYFFKER 

        70         80         90        100        110        120 
EEFEEMIRNE KLLEWAEFVG NYYGTPIDYV EKTLQEGKDV FLEIEVQGAI QVKKAFPEGV 

       130        140        150        160        170        180 
FIFLAPPSLS ELKNRIVGRG TETEDVIENR LTVAKEEIDM MDAYDYVVEN DQVELACERI 

       190        200 
KAIVVGEHCR RERVAKYYKE MTEGL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000001 Genomic DNA. Translation: AAU16637.1. Different initiation.
RefSeqYP_085212.1. NC_006274.1.

3D structure databases

ProteinModelPortalQ636F5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING288681.BCZK3630.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU16637; AAU16637; BCE33L3630.
GeneID3023717.
KEGGbcz:BCZK3630.
PATRIC18891012. VBIBacCer95304_3844.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0194.
KOK00942.
OrthoDBEOG6CP410.
ProtClustDBPRK00300.

Enzyme and pathway databases

BioCycBCER288681:GHG7-3693-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00328. Guanylate_kinase.
InterProIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR03263. guanyl_kin. 1 hit.
PROSITEPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKGUA_BACCZ
AccessionPrimary (citable) accession number: Q636F5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: April 16, 2014
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families