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Q636E4 (Q636E4_BACCZ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Orotate phosphoribosyltransferase 2 HAMAP MF_01208
Short name=OPRT 2 HAMAP MF_01208
Short name=OPRTase 2 HAMAP MF_01208
EC=2.4.2.10 HAMAP MF_01208
Gene names
Name:pyrE EMBL AAU16626.1
Synonyms:pyrE2 HAMAP MF_01208
Ordered Locus Names:BCE33L3641
OrganismBacillus cereus (strain ZK / E33L) [Complete proteome] [HAMAP] EMBL AAU16626.1
Taxonomic identifier288681 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) By similarity. HAMAP MF_01208 SAAS SAAS004467

Catalytic activity

Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_01208 SAAS SAAS023031

Cofactor

Magnesium By similarity. HAMAP MF_01208

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2. HAMAP MF_01208 SAAS SAAS023031

Subunit structure

Homodimer By similarity. HAMAP MF_01208 SAAS SAAS004467

Sequence similarities

Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily. HAMAP MF_01208

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region120 – 12895-phosphoribose 1-diphosphate binding By similarity HAMAP MF_01208

Sites

Binding site9415-phosphoribose 1-diphosphate; shared with dimeric partner By similarity HAMAP MF_01208
Binding site9815-phosphoribose 1-diphosphate; shared with dimeric partner By similarity HAMAP MF_01208
Binding site10015-phosphoribose 1-diphosphate; shared with dimeric partner By similarity HAMAP MF_01208
Binding site1241Orotate By similarity HAMAP MF_01208

Sequences

Sequence LengthMass (Da)Tools
Q636E4 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 63CF9AD3FC9BCBB5

FASTA21022,716
        10         20         30         40         50         60 
MKKEIASHLL EIGAVFLQPN DPFTWSSGMK SPIYCDNRLT LSYPKVRQAI AAGLEELIKE 

        70         80         90        100        110        120 
HFPTVEVIAG TATAGIAHAA WVSDRMDLPM CYVRSKAKGH GKGNQIEGKA EKGQKVIVVE 

       130        140        150        160        170        180 
DLISTGGSAI TCVEALREAG CEVLGIVSIF TYELEAGKEK LEAANVASYS LSDYSALTEV 

       190        200        210 
AAEKGMIGQA ETKKLQEWRK NPADEAWITA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000001 Genomic DNA. Translation: AAU16626.1.
RefSeqYP_085223.1. NC_006274.1.

3D structure databases

ProteinModelPortalQ636E4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ636E4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000042035; EBBACP00000040936; EBBACG00000042026.
GeneID3026876.
GenomeReviewsGene locus BCE33L3641 in contig CP000001_GR.
KEGGbcz:BCZK3641.
PATRIC18891034. VBIBacCer95304_3855.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0461.
GeneTreeEBGT00050000002725.
HOGENOMHBG404341.
OMALPMTYVR.
PhylomeDBQ636E4.
ProtClustDBPRK00455.

Family and domain databases

HAMAPMF_01208. PyrE.
[Tree]
InterProIPR004467. Or_phspho_trans_clade-1.
IPR023031. Orotate_PribosylTferase.
IPR000836. PRibTrfase.
[Graphical view]
KOK00762.
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR00336. PyrE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ636E4_BACCZ
AccessionPrimary (citable) accession number: Q636E4
Entry history
Integrated into UniProtKB/TrEMBL: October 25, 2004
Last sequence update: October 25, 2004
Last modified: December 14, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info