Q635W3 (TGL_BACCZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-glutamine gamma-glutamyltransferase
EC=2.3.2.13

Alternative name(s):
Transglutaminase
Short name=TGase

Gene names

Name:	tgl
Ordered Locus Names:	BCE33L3723

Organism

Bacillus cereus (strain ZK / E33L) [Complete proteome] [HAMAP]

Taxonomic identifier

288681 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › Bacillus cereus

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links By similarity. HAMAP-Rule MF_00727
Catalytic activity	Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3. HAMAP-Rule MF_00727
Sequence similarities	Belongs to the bacillus TGase family.

Ontologies

Keywords
Biological process	Sporulation
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: HAMAP
Molecular_function	protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	Protein-glutamine gamma-glutamyltransferase HAMAP-Rule MF_00727		PRO_1000045888

Sequences

	Sequence		Length	Mass (Da)
	Q635W3 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 889EA7E81E3D8B9D	FASTA	276	31,460
	10 20 30 40 50 60 MIVIGRSIVH PYITNEYEPF AAEKQQILSI MAGNQEIYSF RTSDELSFDL NLRVNIITSA 70 80 90 100 110 120 LELFQSGFQF RTFQQSFCNP QYWKRTSLGG FELLPNIPPS IAIQDIFKNG KLYGTECATA 130 140 150 160 170 180 MIIIFYKALL SLYEEETFNR LFANLLLYTW DYDQDLKLIT KTGGDLVPGD LVYFKNPQVN 190 200 210 220 230 240 PATIEWQGEN TIYLGNFFFY GHGVGVKTKE EIIYALNERR VPYAFISAFL TDTITRIDSR 250 260 270 LMSYHASPST PQTSIGFIPI RDDAIVATVG NTTTVY

References

[1]

"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis." Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P. , Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P. J. Bacteriol. 188:3382-3390(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ZK / E33L.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000001 Genomic DNA. Translation: AAU16541.1.
RefSeq	YP_085304.1. NC_006274.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	288681.BCZK3723.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAU16541; AAU16541; BCE33L3723.
GeneID	3024347.
KEGG	bcz:BCZK3723.
PATRIC	18891198. VBIBacCer95304_3937.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG12337.
KO	K00686.
OMA	FECATAI.
ProtClustDB	PRK03187.
Enzyme and pathway databases
BioCyc	BCER288681:GHG7-4211-MONOMER.
Family and domain databases
HAMAP	MF_00727. Tgl.
InterPro	IPR020916. Gln_gamma-glutamylTfrase_bac. [Graphical view]
ProDom	PD119415. PD119415. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

TGL_BACCZ

Accession

Primary (citable) accession number: Q635W3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2004
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program