Reviewed, UniProtKB/Swiss-Prot Q635W3 (TGL_BACCZ)

Names and origin

Protein names

Recommended name:
    Protein-glutamine gamma-glutamyltransferase
    EC=2.3.2.13
Alternative name(s):
    Transglutaminase
      Short name=TGase

Gene names

Name:	tgl
Ordered Locus Names:	BCE33L3723

Organism

Bacillus cereus (strain ZK / E33L) [Complete proteome] [HAMAP]

Taxonomic identifier

288681 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links By similarity.
Catalytic activity	Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).
Sequence similarities	Belongs to the bacillus TGase family.

Ontologies

Keywords
Biological process	Sporulation
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: HAMAP
Molecular function	acyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	Protein-glutamine gamma-glutamyltransferase		PRO_1000045888

Sequences

	Sequence		Length	Mass (Da)
	Q635W3-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 889EA7E81E3D8B9D	FASTA	276	31,460
	10 20 30 40 50 60 MIVIGRSIVH PYITNEYEPF AAEKQQILSI MAGNQEIYSF RTSDELSFDL NLRVNIITSA 70 80 90 100 110 120 LELFQSGFQF RTFQQSFCNP QYWKRTSLGG FELLPNIPPS IAIQDIFKNG KLYGTECATA 130 140 150 160 170 180 MIIIFYKALL SLYEEETFNR LFANLLLYTW DYDQDLKLIT KTGGDLVPGD LVYFKNPQVN 190 200 210 220 230 240 PATIEWQGEN TIYLGNFFFY GHGVGVKTKE EIIYALNERR VPYAFISAFL TDTITRIDSR 250 260 270 LMSYHASPST PQTSIGFIPI RDDAIVATVG NTTTVY

References

[1]

"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis." Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P. , Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P. J. Bacteriol. 188:3382-3390(2006) [PubMed: 16621833] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000001 Genomic DNA. Translation: AAU16541.1.
RefSeq	YP_085304.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3024347.
GenomeReviews	Gene locus BCE33L3723 in contig CP000001_GR.
KEGG	bcz:BCZK3723.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q635W3.
Enzyme and pathway databases
BioCyc	BCER288681:BCE33L3723-MON.
Family and domain databases
HAMAP	MF_00727. [Tree]
ProtoNet	Search...

Entry information

Entry name

TGL_BACCZ

Accession

Primary (citable) accession number: Q635W3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2004
Last modified:	November 25, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)