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Protein
Submitted name:

TAP2

Gene

TAP2U

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotationImported, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
TAP2Imported
Submitted name:
Transporter 2 ATP-binding cassette sub-family BImported
Gene namesi
Name:TAP2UImported
Synonyms:Tap2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei58 – 7922HelicalSequence analysisAdd
BLAST
Transmembranei99 – 11921HelicalSequence analysisAdd
BLAST
Transmembranei149 – 16921HelicalSequence analysisAdd
BLAST
Transmembranei189 – 21628HelicalSequence analysisAdd
BLAST
Transmembranei270 – 28617HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence analysisAdd
BLAST
Chaini29 – 703675Sequence analysisPRO_5007707217Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000067594.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini153 – 435283ABC transmembrane type-1InterPro annotationAdd
BLAST
Domaini468 – 702235ABC transporterInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transporter domain.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0058. Eukaryota.
COG1132. LUCA.
HOVERGENiHBG008358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR013305. ABC_Tap-like.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
IPR005293. Tap2/ABCB3.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
PRINTSiPR01897. TAP2PROTEIN.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
TIGRFAMsiTIGR00958. 3a01208. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q63522-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSYPRPWA SLLLVDLALL GLLQRSLGTL LPPGLPGLWL EGTLRLGVLW
60 70 80 90 100
GLLKVGGLLR LVGTFLPLLC LTTPLFFSLR ALVGSTMSTS VLRVASASWG
110 120 130 140 150
WLLAGYVAAA LSLAVWAVLS PAGAQEKEPG QENNRALMIR LLRLSKPDLP
160 170 180 190 200
FLIVAFIFLA MAVWGETLIP HYSGRVIDIL GGDFDPDAFA SAIFFMCLFS
210 220 230 240 250
VGSSLSAGCR GGSFLFTMSR INLRIREQLF SSLLRQDLAF FQETKTGELN
260 270 280 290 300
SRLSSDTSLM SRWLPFNANI LLRSLVKVVG LYYFMLQVSP RLTFLSLLDL
310 320 330 340 350
PLTIAAEKVY NPRHQAVLKE IQDVVAKAGQ VVREAVGGLQ TVRSFGAEEQ
360 370 380 390 400
EVSRYKEALE RCRQLWWRRD LEKELYLVIR RVMALGMQVL ILNCGVQQIL
410 420 430 440 450
AGEVTRGGLL SFLLYQEEVG HHVRNLVYMY GDMLSNVGAA EKVFSYLDRR
460 470 480 490 500
PNLPKPGTLA PPRVEGRVEF QDVSFSYPSR PEKPVLQGLT FTLHPGKVTA
510 520 530 540 550
LVGPNGSGKS TVAALLQNLY QPTGGKVLLD GEPLVQYDHH YLHRQVVLVG
560 570 580 590 600
QEPVLFSGSV KDNIAYGLRD CEDAQVMAAA QAACADDFIG EMTNGINTEI
610 620 630 640 650
GEKGSQLAVG QKQRLAIARA LVRNPRVLIL DEATSALDAE CEQALQTWRS
660 670 680 690 700
QEDRTMLVIA HRLHTVQNAD QVLVLKQGQL VEHDQLRDEQ DVYAHLVQQR

LEA
Length:703
Mass (Da):77,723
Last modified:November 1, 1996 - v1
Checksum:iD51FB2DB656B81B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC222911 mRNA. Translation: AGV39008.1.
X75307 mRNA. Translation: CAA53055.1.
UniGeneiRn.202962.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC222911 mRNA. Translation: AGV39008.1.
X75307 mRNA. Translation: CAA53055.1.
UniGeneiRn.202962.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000067594.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0058. Eukaryota.
COG1132. LUCA.
HOVERGENiHBG008358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR013305. ABC_Tap-like.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
IPR005293. Tap2/ABCB3.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
PRINTSiPR01897. TAP2PROTEIN.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
TIGRFAMsiTIGR00958. 3a01208. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Coadwell W.J.
    Submitted (SEP-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PVG.R8Imported.
    Tissue: CON A activated lymphocytesImported.
  2. "The distribution of TAP2 Alleles amongst laboratory RAT RT1 Haplotypes."
    Joly E., Deverson E.V., Coadwell W.L., Gunther E., Howard J.C., Butcher G.W.
    Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PVG.R8Imported.
    Tissue: CON A activated lymphocytesImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DA.1UImported.

Entry informationi

Entry nameiQ63522_RAT
AccessioniPrimary (citable) accession number: Q63522
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.