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Q634D6 (APT_BACCZ) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Adenine phosphoribosyltransferase
Short name=APRT
EC=2.4.2.7
Gene names
Name:apt
Ordered Locus Names:BCE33L4152
OrganismBacillus cereus (strain ZK / E33L) [Complete proteome] [HAMAP]
Taxonomic identifier288681 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length170 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. HAMAP MF_00004

Catalytic activity

AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00004

Pathway

Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1. HAMAP MF_00004

Subunit structure

Homodimer By similarity. HAMAP MF_00004

Subcellular location

Cytoplasm HAMAP MF_00004.

Sequence similarities

Belongs to the purine/pyrimidine phosphoribosyltransferase family.

Ontologies

Keywords
   Biological processPurine salvage
   Cellular componentCytoplasm
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processadenine salvage

Inferred from electronic annotation. Source: InterPro

purine ribonucleoside salvage

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionadenine phosphoribosyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 170170Adenine phosphoribosyltransferase HAMAP MF_00004
PRO_0000149348

Sequences

Sequence LengthMass (Da)Tools
Q634D6 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: A491A98F47D58FF7

FASTA17018,630
        10         20         30         40         50         60 
MDFKQHIAIV PDYPKEGIVF KDITPLMNDG KAYKAATDAI VEYAKERDID VVVGPEARGF 

        70         80         90        100        110        120 
IIGCPVSYAL EVGFAPVRKL GKLPREVITV DYGKEYGKDV LTIHKDAIKP GQRVLITDDL 

       130        140        150        160        170 
LATGGTIEAT IKLVEELGGV VAGIAFLVEL TYLDGRKMLD GYDVLVLEKY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000001 Genomic DNA. Translation: AAU16117.1.
RefSeqYP_085731.1. NC_006274.1.

3D structure databases

ProteinModelPortalQ634D6.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ634D6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000041286; EBBACP00000040187; EBBACG00000041277.
GeneID3026169.
GenomeReviewsGene locus BCE33L4152 in contig CP000001_GR.
KEGGbcz:BCZK4152.
PATRIC18892129. VBIBacCer95304_4401.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0503.
GeneTreeEBGT00050000001499.
HOGENOMHBG703830.
OMAGMEARGF.
ProtClustDBPRK02304.

Enzyme and pathway databases

BioCycBCER288681:BCE33L4152-MONOMER.

Family and domain databases

HAMAPMF_00004. Aden_phosphoribosyltr.
[Tree]
InterProIPR005764. Ade_phspho_trans.
IPR000836. PRibTrfase.
[Graphical view]
KOK00759.
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01090. Apt. 1 hit.
PROSITEPS00103. PUR_PYR_PR_TRANSFER. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAPT_BACCZ
AccessionPrimary (citable) accession number: Q634D6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 25, 2004
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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