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Protein
Submitted name:

RAB38, member RAS oncogene family

Gene

Rab38

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GDP binding Source: RGD
  • GTPase activity Source: RGD
  • GTP binding Source: RGD

GO - Biological processi

  • endosome to melanosome transport Source: Ensembl
  • melanosome assembly Source: Ensembl
  • mitochondrion organization Source: Ensembl
  • organelle organization Source: RGD
  • phagosome acidification Source: Ensembl
  • platelet dense granule organization Source: RGD
  • protein localization to membrane Source: Ensembl
  • small GTPase mediated signal transduction Source: InterPro
  • vesicle-mediated transport Source: RGD

Enzyme and pathway databases

ReactomeiR-RNO-8873719. RAB geranylgeranylation.
R-RNO-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Submitted name:
RAB38, member RAS oncogene familyImported
Submitted name:
Rab-related GTP-binding proteinImported
Submitted name:
Rab38, member of RAS oncogene familyImported
Gene namesi
Name:Rab38Imported
ORF Names:rCG_39383Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi628752. Rab38.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: RGD
  • cytosol Source: RGD
  • early endosome Source: Ensembl
  • ER-mitochondrion membrane contact site Source: Ensembl
  • lysosome Source: Ensembl
  • melanosome membrane Source: Ensembl
  • mitochondrion Source: Ensembl
  • phagocytic vesicle Source: Ensembl
  • trans-Golgi network Source: InterPro
  • vesicle Source: RGD

Expressioni

Gene expression databases

BgeeiENSRNOG00000016769.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022538.

Structurei

3D structure databases

ProteinModelPortaliQ63483.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4423. Eukaryota.
ENOG410YITC. LUCA.
GeneTreeiENSGT00760000119125.
HOGENOMiHOG000233968.
HOVERGENiHBG009351.
KOiK07923.
OMAiKRYVHHN.
OrthoDBiEOG091G0K53.
TreeFamiTF324491.

Family and domain databases

CDDicd04107. Rab32_Rab38. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR030697. Rab29/Rab38/Rab32.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q63483-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTPHKEHLY KLLVIGDLGV GKTSIIKRYV HQNFSSHYRA TIGVDFALKV
60 70 80 90 100
LHWDPETVVR LQLWDIAGQE RFGNMTRVYY REAMGAFIVF DVTRPATFEA
110 120 130 140 150
VAKWKNDLDS KLTLPNGKPV SVVLLANKCD QGKDVLVNNG LKMDQFCKEH
160 170 180 190 200
GFVGWFETSA KENINIDEAS RCLVKHILAN ECDFIESIEP DIVKPHLTSP
210
KVVSCSGCAK S
Length:211
Mass (Da):23,778
Last modified:November 1, 1996 - v1
Checksum:i61F852788F1B6E31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07071940 Genomic DNA. No translation available.
AC099288 Genomic DNA. No translation available.
M94043 mRNA. Translation: AAA42000.1.
BC070513 mRNA. Translation: AAH70513.1.
CH473956 Genomic DNA. Translation: EDM18585.1.
RefSeqiNP_665717.1. NM_145774.2.
UniGeneiRn.9824.

Genome annotation databases

EnsembliENSRNOT00000022538; ENSRNOP00000022538; ENSRNOG00000016769.
GeneIDi252916.
KEGGirno:252916.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07071940 Genomic DNA. No translation available.
AC099288 Genomic DNA. No translation available.
M94043 mRNA. Translation: AAA42000.1.
BC070513 mRNA. Translation: AAH70513.1.
CH473956 Genomic DNA. Translation: EDM18585.1.
RefSeqiNP_665717.1. NM_145774.2.
UniGeneiRn.9824.

3D structure databases

ProteinModelPortaliQ63483.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022538.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000022538; ENSRNOP00000022538; ENSRNOG00000016769.
GeneIDi252916.
KEGGirno:252916.

Organism-specific databases

CTDi23682.
RGDi628752. Rab38.

Phylogenomic databases

eggNOGiKOG4423. Eukaryota.
ENOG410YITC. LUCA.
GeneTreeiENSGT00760000119125.
HOGENOMiHOG000233968.
HOVERGENiHBG009351.
KOiK07923.
OMAiKRYVHHN.
OrthoDBiEOG091G0K53.
TreeFamiTF324491.

Enzyme and pathway databases

ReactomeiR-RNO-8873719. RAB geranylgeranylation.
R-RNO-8876198. RAB GEFs exchange GTP for GDP on RABs.

Gene expression databases

BgeeiENSRNOG00000016769.

Family and domain databases

CDDicd04107. Rab32_Rab38. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR030697. Rab29/Rab38/Rab32.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ63483_RAT
AccessioniPrimary (citable) accession number: Q63483
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 12, 2017
This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.