Q63380 (Q63380_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Transporter RuleBase RU003732

Gene names

Name:	Slc6a2 RGD 621822
Synonyms:	NET EMBL CAA73665.1

Organism

Rattus norvegicus (Rat) EMBL CAA73665.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	617 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the sodium:neurotransmitter symporter (SNF) family. RuleBase RU003732

Ontologies

Keywords
Biological process	Symport RuleBase RU003732 SAAS SAAS000175 Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000175
Gene Ontology (GO)
Cellular_component	integral to plasma membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	neurotransmitter:sodium symporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q63380 [UniParc]. Last modified November 1, 1998. Version 2. Checksum: BD35E6EFD207D91C	FASTA	617	69,231
	10 20 30 40 50 60 MLLARMKPQV QPELGGADQL PEQPLRPCKT ADLLVVKERN GVQCLLASQD GDAQPRETWG 70 80 90 100 110 120 KEIDFLLSVV GFAVDLANVW RFPYLCYKNG GGAFLIPYTL FLIIAGMPLF YMELALGQFN 130 140 150 160 170 180 REGAATVWKI CPFFKGVGYA VILIALYVGF YYNVIIAWSL YYLFASFTLN LPWTNCGHAW 190 200 210 220 230 240 NSPNCTDPKL LNASVLGDHT KYSKYKFTPA AEFYERGVLH LHESSGIHDI GLPQWQLLLC 250 260 270 280 290 300 LMVVIVVLYF SLWKGVKTSG KVVWITATLP YFVLFVLLVH GVTLPGASNG INAYLHIDFY 310 320 330 340 350 360 RLKEATVWID AATQIFFSLG AGFGVLIAFA SYNKFDNNCY RDALLTSTIN CVTSFISGFA 370 380 390 400 410 420 IFSILGYMAH EHKVKIEDVA TEGAGLVFVL YPEAISTLSG STFWAVLFFL MLLALGLDSS 430 440 450 460 470 480 MGGMEAVITG LADDFQVLKR HRKLFTCAVT LGTFLLAMFC ITKGGIYVLT LLDTFAAGTS 490 500 510 520 530 540 ILFAVLMEAI GVSWFYGVDR FSNDIQQMMG FKPGLYWRLC WKFVSPAFLL FVVVVSIINF 550 560 570 580 590 600 KPLTYDDYVY PPWANWVGWG IALSSMILVP AYVIYKFFSI RGSLWERVAY GITPENEHHL 610 VAQRDVRQFQ LRHWLAI

References

[1]	"The rat norepinephrine transporter: molecular cloning from PC12 cells and functional expression." Bruess M., Poerzgen P., Bryan-Lluka L.J., Boenisch H. Mol. Brain Res. 52:257-262(1997) Cited for: NUCLEOTIDE SEQUENCE. Tissue: Pheocromocytoma EMBL CAA73665.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y13223 mRNA. Translation: CAA73665.1.
IPI	IPI00326777.
UniGene	Rn.14577.
3D structure databases
ProteinModelPortal	Q63380.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	COG0733.
HOGENOM	HOG000116406.
HOVERGEN	HBG071421.
InParanoid	Q63380.
Gene expression databases
Genevestigator	Q63380.
Family and domain databases
InterPro	IPR000175. Na/ntran_symport. IPR002435. Na/ntran_symport_noradrenaline. [Graphical view]
PANTHER	PTHR11616. PTHR11616. 1 hit.
Pfam	PF00209. SNF. 1 hit. [Graphical view]
PRINTS	PR00176. NANEUSMPORT. PR01201. NORTRANSPORT.
PROSITE	PS00610. NA_NEUROTRAN_SYMP_1. 1 hit. PS00754. NA_NEUROTRAN_SYMP_2. 1 hit. PS50267. NA_NEUROTRAN_SYMP_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChEMBL	CHEMBL6184.

Entry information

Entry name

Q63380_RAT

Accession

Primary (citable) accession number: Q63380

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1998
Last modified:	March 6, 2013
This is version 71 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)