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Protein

Transporter

Gene

NET

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processSymportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:NETImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei65 – 83HelicalSequence analysisAdd BLAST19
Transmembranei95 – 116HelicalSequence analysisAdd BLAST22
Transmembranei137 – 164HelicalSequence analysisAdd BLAST28
Transmembranei232 – 250HelicalSequence analysisAdd BLAST19
Transmembranei262 – 287HelicalSequence analysisAdd BLAST26
Transmembranei307 – 332HelicalSequence analysisAdd BLAST26
Transmembranei344 – 369HelicalSequence analysisAdd BLAST26
Transmembranei389 – 415HelicalSequence analysisAdd BLAST27
Transmembranei444 – 469HelicalSequence analysisAdd BLAST26
Transmembranei475 – 498HelicalSequence analysisAdd BLAST24
Transmembranei519 – 538HelicalSequence analysisAdd BLAST20
Transmembranei558 – 578HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL6184.

PTM / Processingi

Proteomic databases

PaxDbiQ63380.

Structurei

3D structure databases

ProteinModelPortaliQ63380.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3659. Eukaryota.
COG0733. LUCA.
HOGENOMiHOG000116406.
HOVERGENiHBG071421.

Family and domain databases

InterProiView protein in InterPro
IPR000175. Na/ntran_symport.
IPR002435. Na/ntran_symport_noradrenaline.
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiView protein in Pfam
PF00209. SNF. 1 hit.
PRINTSiPR00176. NANEUSMPORT.
PR01201. NORTRANSPORT.
PROSITEiView protein in PROSITE
PS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q63380-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLARMKPQV QPELGGADQL PEQPLRPCKT ADLLVVKERN GVQCLLASQD
60 70 80 90 100
GDAQPRETWG KEIDFLLSVV GFAVDLANVW RFPYLCYKNG GGAFLIPYTL
110 120 130 140 150
FLIIAGMPLF YMELALGQFN REGAATVWKI CPFFKGVGYA VILIALYVGF
160 170 180 190 200
YYNVIIAWSL YYLFASFTLN LPWTNCGHAW NSPNCTDPKL LNASVLGDHT
210 220 230 240 250
KYSKYKFTPA AEFYERGVLH LHESSGIHDI GLPQWQLLLC LMVVIVVLYF
260 270 280 290 300
SLWKGVKTSG KVVWITATLP YFVLFVLLVH GVTLPGASNG INAYLHIDFY
310 320 330 340 350
RLKEATVWID AATQIFFSLG AGFGVLIAFA SYNKFDNNCY RDALLTSTIN
360 370 380 390 400
CVTSFISGFA IFSILGYMAH EHKVKIEDVA TEGAGLVFVL YPEAISTLSG
410 420 430 440 450
STFWAVLFFL MLLALGLDSS MGGMEAVITG LADDFQVLKR HRKLFTCAVT
460 470 480 490 500
LGTFLLAMFC ITKGGIYVLT LLDTFAAGTS ILFAVLMEAI GVSWFYGVDR
510 520 530 540 550
FSNDIQQMMG FKPGLYWRLC WKFVSPAFLL FVVVVSIINF KPLTYDDYVY
560 570 580 590 600
PPWANWVGWG IALSSMILVP AYVIYKFFSI RGSLWERVAY GITPENEHHL
610
VAQRDVRQFQ LRHWLAI
Length:617
Mass (Da):69,231
Last modified:November 1, 1998 - v2
Checksum:iBD35E6EFD207D91C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y13223 mRNA. Translation: CAA73665.1.
UniGeneiRn.14577.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ63380_RAT
AccessioniPrimary (citable) accession number: Q63380
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1998
Last modified: July 5, 2017
This is version 89 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)