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Protein

Neurexin-2

Gene

Nrxn2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi335CalciumBy similarity1
Metal bindingi352Calcium; via carbonyl oxygenBy similarity1
Metal bindingi420Calcium; via carbonyl oxygenBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Neurexin-2
Alternative name(s):
Neurexin II-alpha
Neurexin-2-alpha
Gene namesi
Name:Nrxn2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi620211. Nrxn2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini30 – 1639ExtracellularSequence analysisAdd BLAST1610
Transmembranei1640 – 1660HelicalSequence analysisAdd BLAST21
Topological domaini1661 – 1715CytoplasmicSequence analysisAdd BLAST55

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29By similarityAdd BLAST29
ChainiPRO_000001949630 – 1715Neurexin-2Add BLAST1686

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi60N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi206 ↔ 219By similarity
Disulfide bondi213 ↔ 229By similarity
Disulfide bondi231 ↔ 241By similarity
Glycosylationi338N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi450 ↔ 486By similarity
Disulfide bondi657 ↔ 686By similarity
Disulfide bondi694 ↔ 705By similarity
Disulfide bondi699 ↔ 714By similarity
Disulfide bondi716 ↔ 726By similarity
Glycosylationi844N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi1068 ↔ 1096By similarity
Disulfide bondi1103 ↔ 1114By similarity
Disulfide bondi1108 ↔ 1123By similarity
Disulfide bondi1125 ↔ 1135By similarity
Glycosylationi1239N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ63374.
PRIDEiQ63374.

PTM databases

iPTMnetiQ63374.
PhosphoSitePlusiQ63374.

Expressioni

Tissue specificityi

Brain (neuronal synapse).

Interactioni

Subunit structurei

The laminin G-like domain 1 binds to NXPH1. Isoforms alpha 2C bind to alpha-dystroglycan. Interacts with PATJ. Interacts with CBLN1, CBLN2 and, less avidly, with CBLN4 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi250509. 3 interactors.
IntActiQ63374. 6 interactors.
MINTiMINT-1538394.
STRINGi10116.ENSRNOP00000063600.

Structurei

3D structure databases

ProteinModelPortaliQ63374.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 206Laminin G-like 1PROSITE-ProRule annotationAdd BLAST177
Domaini202 – 242EGF-like 1PROSITE-ProRule annotationAdd BLAST41
Domaini289 – 486Laminin G-like 2PROSITE-ProRule annotationAdd BLAST198
Domaini493 – 686Laminin G-like 3PROSITE-ProRule annotationAdd BLAST194
Domaini690 – 727EGF-like 2PROSITE-ProRule annotationAdd BLAST38
Domaini732 – 907Laminin G-like 4PROSITE-ProRule annotationAdd BLAST176
Domaini921 – 1096Laminin G-like 5PROSITE-ProRule annotationAdd BLAST176
Domaini1099 – 1136EGF-like 3PROSITE-ProRule annotationAdd BLAST38
Domaini1140 – 1348Laminin G-like 6PROSITE-ProRule annotationAdd BLAST209

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1371 – 1374Poly-Thr4
Compositional biasi1377 – 1380Poly-Thr4
Compositional biasi1447 – 1450Poly-Pro4
Compositional biasi1647 – 1650Poly-Ala4

Sequence similaritiesi

Belongs to the neurexin family.Curated
Contains 3 EGF-like domains.PROSITE-ProRule annotation
Contains 6 laminin G-like domains.PROSITE-ProRule annotation

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3514. Eukaryota.
ENOG410XNU6. LUCA.
HOGENOMiHOG000230481.
HOVERGENiHBG052670.
InParanoidiQ63374.
KOiK07377.

Family and domain databases

Gene3Di2.60.120.200. 6 hits.
InterProiIPR013320. ConA-like_dom.
IPR000742. EGF-like_dom.
IPR001791. Laminin_G.
IPR003585. Neurexin-like.
IPR027160. NRXN2.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF593. PTHR10127:SF593. 3 hits.
PfamiPF02210. Laminin_G_2. 6 hits.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00181. EGF. 3 hits.
SM00282. LamG. 6 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 7 hits.
PROSITEiPS50026. EGF_3. 3 hits.
PS50025. LAM_G_DOMAIN. 6 hits.
[Graphical view]

Sequences (18)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 18 isoformsi produced by alternative promoter usage and alternative splicing. AlignAdd to basket

Note: Two isoform types, alpha-type and beta-type are produced by alternative promoter usage. In addition there are at least five major alternatively spliced sites, each of which may be spliced in up to three different ways. Additional isoforms may derive from a minor cytoplasmic splice site 6. Combinatorial splicing at each of these six sites may lead to the generation of at least 216 isoforms but for simplicity only individual splice events are explicitly described below. Beta-type isoforms share the possibility of alternative splicing at sites 4, 5 and 6. Experimental confirmation may be lacking for some isoforms.2 Publications
Isoform 1a (identifier: Q63374-1) [UniParc]FASTAAdd to basket
Also known as: Alpha-1A2A3A4A5A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MALGSRWRPP PQLPPLLLLL ALVAGVRGLE FGGGPGQWAR YARWAGAAST
60 70 80 90 100
GELSFSLRTN ATRALLLYLD DGGDCDFLEL LLVDGRLRLR FTLSCAEPAT
110 120 130 140 150
LQLDTPVADD RWHMVLLTRD ARRTALAVDG EARAAEVRSK RREMQVASDL
160 170 180 190 200
FVGGIPPDVR LSALTLSTVK YEPPFRGLLA NLKLGERPPA LLGSQGLRGA
210 220 230 240 250
AADPLCAPAR NPCANGGLCT VLAPGEVGCD CSHTGFGGKF CSEGEHPMEG
260 270 280 290 300
PAHLTLNSPV GSLLFSEGGA GRGGAGDVHQ PTKGKEEFVA TFKGNEFFCY
310 320 330 340 350
DLSHNPIQSS TDEITLAFRT LQRNGLMLHT GKSADYVNLS LKSGAVWLVI
360 370 380 390 400
NLGSGAFEAL VEPVNGKFND NAWHDVRVTR NLRQHAGIGH AMVNKLHYLV
410 420 430 440 450
TISVDGILTT TGYTQEDYTM LGSDDFFYIG GSPNTADLPG SPVSNNFMGC
460 470 480 490 500
LKDVVYKNND FKLELSRLAK EGDPKMKLQG DLSFRCEDVA ALDPVTFESP
510 520 530 540 550
EAFVALPRWS AKRTGSISLD FRTTEPNGLL LFSQGRRAGA GVGSHSSSQR
560 570 580 590 600
ADYFAMELLD GYLYLLLDMG SGGIKLRASS RKVNDGEWCH VDFQRDGRKG
610 620 630 640 650
SISVNSRSTP FLATGESEVL DLESELYLGG LPEGGRVDLP LPPEVWTAAL
660 670 680 690 700
RAGYVGCVRD LFIDGRSRDL RGLAEAQGAV GVAPFCSRET LKQCASAPCR
710 720 730 740 750
NGGICREGWN RFVCDCIGTG FLGRVCEREA TVLSYDGSMY MKIMLPNAMH
760 770 780 790 800
TEAEDVSLRF MSQRAYGLMM ATTSRESADT LRLELDGGQM KLTVNLDCLR
810 820 830 840 850
VGCAPSAAGK GPETLFAGHK LNDNEWHTVR VVRRGKSLQL SVDNVTVEGQ
860 870 880 890 900
MAGAHTRLEF HNIETGIMTE RRFISVVPSN FIGHLSGLVF NGQPYMDQCK
910 920 930 940 950
DGDITYCELN ARFGLRAIVA DPVTFKSRSS YLALATLQAY ASMHLFFQFK
960 970 980 990 1000
TTAPDGLLLF NSGNGNDFIV IELVKGYIHY VFDLGNGPSL MKGNSDKPVN
1010 1020 1030 1040 1050
DNQWHNVVVS RDPGNVHTLK IDSRTVTQHS NGARNLDLKG ELYIGGLSKN
1060 1070 1080 1090 1100
MFSNLPKLVA SRDGFQGCLA SVDLNGRLPD LIADALHRIG QVERGCDGPS
1110 1120 1130 1140 1150
TTCTEESCAN QGVCLQQWDG FTCDCTMTSY GGPVCNDPGT TYIFGKGGAL
1160 1170 1180 1190 1200
ITYTWPPNDR PSTRMDRLAV GFSTHQRSAV LVRVDSASGL GDYLQLHIDQ
1210 1220 1230 1240 1250
GTVGVIFNVG TDDITIDEPN AIVSDGKYHV VRFTRSGGNA TLQVDSWPVN
1260 1270 1280 1290 1300
ERYPAGNFDN ERLAIARQRI PYRLGRVVDE WLLDKGRQLT IFNSQAAIKI
1310 1320 1330 1340 1350
GGRDQGRPFQ GQVSGLYYNG LKVLALAAES DPNVRTEGHL RLVGEGPSVL
1360 1370 1380 1390 1400
LSAETTATTL LADMATTIME TTTTMATTTT RRGRSPTMRD STTQNTDDLL
1410 1420 1430 1440 1450
VASAECPSDD EDLEECEPST GGELILPIIT EDSLDPPPVA TRSPFVPPPP
1460 1470 1480 1490 1500
TFYPFLTGVG ATQDTLPPPA ARRPSSGGPC QAERDDSDCE EPVEASGFAS
1510 1520 1530 1540 1550
GEVFDSSLPP TDDEDFYTTF PLVTDRTTLL SPRKPAPRPN LRTDGATGAP
1560 1570 1580 1590 1600
GVLLAPSAPA PNLPAGKMNH RDPLQPLLEN PPLGPGVPTA FEPRRPPPLR
1610 1620 1630 1640 1650
PGVTSVPGFP RLPTANPTGP GERGPPGAVE VIRESSSTTG MVVGIVAAAA
1660 1670 1680 1690 1700
LCILILLYAM YKYRNRDEGS YQVDQSRNYI SNSAQSNGAV VKEKAPAAPK
1710
TPSKAKKNKD KEYYV
Length:1,715
Mass (Da):185,169
Last modified:January 23, 2007 - v3
Checksum:iC4A7A4129F25736C
GO
Isoform 2a (identifier: Q63374-2) [UniParc]FASTAAdd to basket
Also known as: Alpha-1B

The sequence of this isoform differs from the canonical sequence as follows:
     250-259: Missing.

Show »
Length:1,705
Mass (Da):184,181
Checksum:i42B136F20A8E312C
GO
Isoform 3a (identifier: Q63374-3) [UniParc]FASTAAdd to basket
Also known as: Alpha-1C

The sequence of this isoform differs from the canonical sequence as follows:
     250-283: Missing.

Show »
Length:1,681
Mass (Da):181,902
Checksum:iB88CFBD700F47847
GO
Isoform 4a (identifier: Q63374-4) [UniParc]FASTAAdd to basket
Also known as: Alpha-2B

The sequence of this isoform differs from the canonical sequence as follows:
     393-399: Missing.

Show »
Length:1,708
Mass (Da):184,301
Checksum:i29AE45D36BC8599E
GO
Isoform 5a (identifier: Q63374-5) [UniParc]FASTAAdd to basket
Also known as: Alpha-2C

The sequence of this isoform differs from the canonical sequence as follows:
     385-399: Missing.

Show »
Length:1,700
Mass (Da):183,526
Checksum:i96BE9160C5D0B080
GO
Isoform 6a (identifier: Q63374-6) [UniParc]FASTAAdd to basket
Also known as: Alpha-3B

The sequence of this isoform differs from the canonical sequence as follows:
     807-809: Missing.

Show »
Length:1,712
Mass (Da):184,970
Checksum:iC68A686D8C3E6DB7
GO
Isoform 7a (identifier: Q63374-7) [UniParc]FASTAAdd to basket
Also known as: Alpha-3C

The sequence of this isoform differs from the canonical sequence as follows:
     797-806: DCLRVGCAPS → G

Show »
Length:1,706
Mass (Da):184,224
Checksum:iA77431B274065E98
GO
Isoform 8a (identifier: Q63374-8) [UniParc]FASTAAdd to basket
Also known as: Alpha-4B

The sequence of this isoform differs from the canonical sequence as follows:
     1256-1285: Missing.

Show »
Length:1,685
Mass (Da):181,573
Checksum:i58831E7E2755CC55
GO
Isoform 9a (identifier: Q63374-9) [UniParc]FASTAAdd to basket
Also known as: Alpha-5B

The sequence of this isoform differs from the canonical sequence as follows:
     1421-1614: Missing.

Show »
Length:1,521
Mass (Da):164,826
Checksum:i358B693C6F80FA7F
GO
Isoform 10a (identifier: Q63374-10) [UniParc]FASTAAdd to basket
Also known as: Alpha-6

The sequence of this isoform differs from the canonical sequence as follows:
     1667-1715: DEGSYQVDQS...KKNKDKEYYV → CRKSPREEKL...RQMQIYIKNK

Show »
Length:1,728
Mass (Da):186,513
Checksum:iA0EC3826D24CDBB4
GO
Isoform 1b (identifier: Q63376-1) [UniParc]FASTAAdd to basket
Also known as: Beta-4A5A
The sequence of this isoform can be found in the external entry Q63376.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:662
Mass (Da):70,547
GO
Isoform 2b (identifier: Q63376-2) [UniParc]FASTAAdd to basket
Also known as: Beta-4A5B
The sequence of this isoform can be found in the external entry Q63376.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:644
Mass (Da):68,688
GO
Isoform 3b (identifier: Q63376-3) [UniParc]FASTAAdd to basket
Also known as: Beta-4B5A
The sequence of this isoform can be found in the external entry Q63376.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:632
Mass (Da):66,950
GO
Isoform 4b (identifier: Q63376-4) [UniParc]FASTAAdd to basket
Also known as: Beta-4B5B
The sequence of this isoform can be found in the external entry Q63376.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:614
Mass (Da):65,092
GO
Isoform 5b (identifier: Q63376-5) [UniParc]FASTAAdd to basket
Also known as: Beta-4A5A6
The sequence of this isoform can be found in the external entry Q63376.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:675
Mass (Da):71,891
GO
Isoform 6b (identifier: Q63376-6) [UniParc]FASTAAdd to basket
Also known as: Beta-4A5B6
The sequence of this isoform can be found in the external entry Q63376.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:657
Mass (Da):70,032
GO
Isoform 7b (identifier: Q63376-7) [UniParc]FASTAAdd to basket
Also known as: Beta-4B5A6
The sequence of this isoform can be found in the external entry Q63376.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:645
Mass (Da):68,294
GO
Isoform 8b (identifier: Q63376-8) [UniParc]FASTAAdd to basket
Also known as: Beta-4B5B6
The sequence of this isoform can be found in the external entry Q63376.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:627
Mass (Da):66,436
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti244G → E in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti244G → E in AAA41707 (PubMed:1621094).Curated1
Sequence conflicti259P → E in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti259P → E in AAA41707 (PubMed:1621094).Curated1
Sequence conflicti277D → N in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti277D → N in AAA41707 (PubMed:1621094).Curated1
Sequence conflicti297F → S in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti297F → S in AAA41707 (PubMed:1621094).Curated1
Sequence conflicti335D → N in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti335D → N in AAA41707 (PubMed:1621094).Curated1
Sequence conflicti349V → I in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti349V → I in AAA41707 (PubMed:1621094).Curated1
Sequence conflicti809G → A in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti809G → A in AAA41707 (PubMed:1621094).Curated1
Sequence conflicti829V → L in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti829V → L in AAA41707 (PubMed:1621094).Curated1
Sequence conflicti987G → S in AAA41706 (PubMed:1621094).Curated1
Sequence conflicti987G → S in AAA41707 (PubMed:1621094).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti434N → L.1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_003510250 – 283Missing in isoform 3a. CuratedAdd BLAST34
Alternative sequenceiVSP_003509250 – 259Missing in isoform 2a. Curated10
Alternative sequenceiVSP_003511385 – 399Missing in isoform 5a. CuratedAdd BLAST15
Alternative sequenceiVSP_003512393 – 399Missing in isoform 4a. Curated7
Alternative sequenceiVSP_003513797 – 806DCLRVGCAPS → G in isoform 7a. Curated10
Alternative sequenceiVSP_003514807 – 809Missing in isoform 6a. Curated3
Alternative sequenceiVSP_0035151256 – 1285Missing in isoform 8a. CuratedAdd BLAST30
Alternative sequenceiVSP_0035161421 – 1614Missing in isoform 9a. CuratedAdd BLAST194
Alternative sequenceiVSP_0035171667 – 1715DEGSY…KEYYV → CRKSPREEKLLPGSAQGLGL DLAKACCVCRCRATCIAGKP LEERGGGRGEGERQMQIYIK NK in isoform 10a. 1 PublicationAdd BLAST49

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M96376 mRNA. Translation: AAA41706.1.
M96376 mRNA. Translation: AAA41707.1.
AABR03000676 Genomic DNA. No translation available.
AABR03002856 Genomic DNA. No translation available.
AABR03004066 Genomic DNA. No translation available.
AABR03004601 Genomic DNA. No translation available.
AABR03004809 Genomic DNA. No translation available.
AABR03005995 Genomic DNA. No translation available.
AABR03006603 Genomic DNA. No translation available.
AABR03006786 Genomic DNA. No translation available.
AABR03008290 Genomic DNA. No translation available.
AABR03009435 Genomic DNA. No translation available.
PIRiC40228.
RefSeqiNP_446298.1. NM_053846.1.
UniGeneiRn.11282.

Genome annotation databases

GeneIDi116595.
KEGGirno:116595.

Keywords - Coding sequence diversityi

Alternative promoter usage, Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M96376 mRNA. Translation: AAA41706.1.
M96376 mRNA. Translation: AAA41707.1.
AABR03000676 Genomic DNA. No translation available.
AABR03002856 Genomic DNA. No translation available.
AABR03004066 Genomic DNA. No translation available.
AABR03004601 Genomic DNA. No translation available.
AABR03004809 Genomic DNA. No translation available.
AABR03005995 Genomic DNA. No translation available.
AABR03006603 Genomic DNA. No translation available.
AABR03006786 Genomic DNA. No translation available.
AABR03008290 Genomic DNA. No translation available.
AABR03009435 Genomic DNA. No translation available.
PIRiC40228.
RefSeqiNP_446298.1. NM_053846.1.
UniGeneiRn.11282.

3D structure databases

ProteinModelPortaliQ63374.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi250509. 3 interactors.
IntActiQ63374. 6 interactors.
MINTiMINT-1538394.
STRINGi10116.ENSRNOP00000063600.

PTM databases

iPTMnetiQ63374.
PhosphoSitePlusiQ63374.

Proteomic databases

PaxDbiQ63374.
PRIDEiQ63374.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi116595.
KEGGirno:116595.

Organism-specific databases

CTDi9379.
RGDi620211. Nrxn2.

Phylogenomic databases

eggNOGiKOG3514. Eukaryota.
ENOG410XNU6. LUCA.
HOGENOMiHOG000230481.
HOVERGENiHBG052670.
InParanoidiQ63374.
KOiK07377.

Family and domain databases

Gene3Di2.60.120.200. 6 hits.
InterProiIPR013320. ConA-like_dom.
IPR000742. EGF-like_dom.
IPR001791. Laminin_G.
IPR003585. Neurexin-like.
IPR027160. NRXN2.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF593. PTHR10127:SF593. 3 hits.
PfamiPF02210. Laminin_G_2. 6 hits.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00181. EGF. 3 hits.
SM00282. LamG. 6 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 7 hits.
PROSITEiPS50026. EGF_3. 3 hits.
PS50025. LAM_G_DOMAIN. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNRX2A_RAT
AccessioniPrimary (citable) accession number: Q63374
Secondary accession number(s): Q63375
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 138 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.