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Q63176 (Q63176_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
DNA topoisomerase IIA EMBL BAA03132.1
Gene names
Name:Top2a RGD 62048
OrganismRattus norvegicus (Rat) EMBL BAA03132.1
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length214 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Molecular functionIsomerase EMBL BAA03132.1
Gene Ontology (GO)
   Biological_processDNA topological change

Inferred from electronic annotation. Source: InterPro

   Cellular_componentchromosome

Inferred from electronic annotation. Source: InterPro

   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

DNA topoisomerase type II (ATP-hydrolyzing) activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAA03132.1
Non-terminal residue2141 EMBL BAA03132.1

Sequences

Sequence LengthMass (Da)Tools
Q63176 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 46A28A1DEA188A5A

FASTA21424,173
        10         20         30         40         50         60 
AQLAGSVAEM SSYHHGEMSL MMTIINLAQN FVGSNNLNLL QPIGQFGTRL HGGKDSASPR 

        70         80         90        100        110        120 
YIFTMLSPLA RLLFPSKDDH TLRFLYDDNQ RVEPEWYILI IPMVLINGAE GIGTGWSCKI 

       130        140        150        160        170        180 
PNFDVREVVN NIRRLLDGEE PLPMLPSYKN YKGTIEELAS NQYVINGEVA ILNSTTIEIT 

       190        200        210 
ELPIRTWTQT YKEQVLEPML NGTEKTPPLI TDYR

« Hide

References

[1]"Molecular cloning of partial cDNAs for rat DNA topoisomerase II isoforms and their differential expression in brain development."
Tsutsui K., Tsutsui K., Okada S., Watanabe M., Shohmori T., Seki S., Inoue Y.
J. Biol. Chem. 268:19076-19083(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Sprague-Dawley EMBL BAA03132.1.
Tissue: Brain EMBL BAA03132.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		D14045 mRNA. Translation: BAA03132.1.
IPIIPI00193944.
UniGeneRn.90996.

3D structure databases

HSSPHSSP built from PDB template 1BJT based on UniProtKB P06786.
ProteinModelPortalQ63176.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

RGD62048. Top2a.

Phylogenomic databases

HOGENOMHOG000216693.
InParanoidQ63176.

Gene expression databases

GenevestigatorQ63176.

Family and domain databases

Gene3D3.30.1360.40. 1 hit.
3.90.199.10. 1 hit.
InterProIPR024946. Arg_repress_C-like.
IPR002205. Topo_IIA_A/C.
IPR013758. Topo_IIA_A/C_ab.
IPR013760. Topo_IIA_like_dom.
[Graphical view]
PfamPF00521. DNA_topoisoIV. 1 hit.
[Graphical view]
SMARTSM00434. TOP4c. 1 hit.
[Graphical view]
SUPFAMSSF56719. Topo_IIA_cen. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ63176_RAT
AccessionPrimary (citable) accession number: Q63176
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 3, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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