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Protein

Dynein heavy chain 7, axonemal

Gene

Dnah7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi165 – 1728ATPSequence analysis
Nucleotide bindingi1361 – 13688ATPSequence analysis
Nucleotide bindingi1642 – 16498ATPSequence analysis
Nucleotide bindingi2009 – 20168ATPSequence analysis
Nucleotide bindingi2374 – 23818ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Motor protein

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Dynein heavy chain 7, axonemal
Alternative name(s):
Axonemal beta dynein heavy chain 7
Axonemal dynein heavy chain b
Ciliary dynein heavy chain 7
Dynein-like protein 7
Gene namesi
Name:Dnah7
Synonyms:Axob, Dlp7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi621798. Dnah7.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Dynein, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 40574057Dynein heavy chain 7, axonemalPRO_0000317667Add
BLAST

Proteomic databases

PaxDbiQ63170.
PRIDEiQ63170.

Expressioni

Tissue specificityi

Detected in brain.1 Publication

Inductioni

Up-regulated during ciliogenesis.1 Publication

Interactioni

Subunit structurei

The dynein complex consists of at least two heavy chains and a number of intermediate and light chains.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016465.

Structurei

3D structure databases

ProteinModelPortaliQ63170.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1323 – 1544222AAA 1By similarityAdd
BLAST
Regioni1604 – 1835232AAA 2By similarityAdd
BLAST
Regioni1971 – 2222252AAA 3By similarityAdd
BLAST
Regioni2335 – 2588254AAA 4By similarityAdd
BLAST
Regioni2605 – 2906302StalkBy similarityAdd
BLAST
Regioni2987 – 3217231AAA 5By similarityAdd
BLAST
Regioni3430 – 3653224AAA 6By similarityAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili716 – 77964Sequence analysisAdd
BLAST
Coiled coili2602 – 264645Sequence analysisAdd
BLAST
Coiled coili2860 – 291657Sequence analysisAdd
BLAST

Domaini

Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other dynein components), and the head or motor domain. The motor contains six tandemly-linked AAA domains in the head, which form a ring. A stalk-like structure (formed by two of the coiled coil domains) protrudes between AAA 4 and AAA 5 and terminates in a microtubule-binding site. A seventh domain may also contribute to this ring; it is not clear whether the N-terminus or the C-terminus forms this extra domain. There are four well-conserved and two non-conserved ATPase sites, one per AAA domain. Probably only one of these (within AAA 1) actually hydrolyzes ATP, the others may serve a regulatory function (By similarity).By similarity

Sequence similaritiesi

Belongs to the dynein heavy chain family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG3595. Eukaryota.
COG5245. LUCA.
HOGENOMiHOG000237308.
HOVERGENiHBG107830.
InParanoidiQ63170.
PhylomeDBiQ63170.

Family and domain databases

Gene3Di3.40.50.300. 5 hits.
InterProiIPR003593. AAA+_ATPase.
IPR026983. DHC_fam.
IPR026979. DNAH7.
IPR024743. Dynein_HC_stalk.
IPR024317. Dynein_heavy_chain_D4_dom.
IPR004273. Dynein_heavy_dom.
IPR013602. Dynein_heavy_dom-2.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10676. PTHR10676. 1 hit.
PTHR10676:SF138. PTHR10676:SF138. 1 hit.
PfamiPF12780. AAA_8. 1 hit.
PF08393. DHC_N2. 1 hit.
PF03028. Dynein_heavy. 1 hit.
PF12777. MT. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 5 hits.

Sequencei

Sequence statusi: Complete.

Q63170-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSEQVRAGS PGSRVPGARR TGAVWTAPSE NLDSSTIPAL CVSLLFPSQP
60 70 80 90 100
LDVVVTMGHN TLGMRQLWKL ALQRPQLLSG STGVKPQWQQ TAPSFHLNVK
110 120 130 140 150
QENPIEPYNV KNEQSYAEYM EHFGKKGKLL DQIDDTRSAP STSRSKVKSP
160 170 180 190 200
HKERENFRST LVNVIMQQDS SLEPDVTDES GIPKATTSAI EKDILRYYYY
210 220 230 240 250
IHHGIDTDNV APMEDSWLEH VLQLVPQHLK VLTNSITVLS DEMREDYLLS
260 270 280 290 300
VKKSIVDFVL KDPREKEDDT KITELPPHRA EMEVLPKPWR RSFLSACSYI
310 320 330 340 350
RDHLNAMNPT MLAVLDLWHS TFKKLRLVDI EEFHNRQDAL ELSGFQNIVI
360 370 380 390 400
KHMESAKETL LKTWFPEVQN IYYQGNKKKQ LPTGDSSAKL ESFFNCAATL
410 420 430 440 450
MTLQLQDLIL VSMQDFTDLI AQPPESIRAF EHPGFIMRLV LDKKAVKFEP
460 470 480 490 500
EFTDYIDILV NVYEIMIKAV SFVPRVETKL YSKWESKSKP TTLKPIILDE
510 520 530 540 550
IIDAHKEKIR EVVLRESVAP TEHLKMYDKY QFLITRQAEQ DIEEFLTQSQ
560 570 580 590 600
NYERLIEEIR KYQKLGEEIQ YTSRKTVRLG MFEMHCEELI RSLVKRADII
610 620 630 640 650
CGKLIAKMFR DHQEVNTMLC EEFEKIAEKA LSTPPNTAEL MEMKAHIQKV
660 670 680 690 700
ETTDMLDLGQ RLVDSKNCLA FLIECVNFSP ADIRLNNSVF QWYGRMGEIF
710 720 730 740 750
DEHRKIIKDK TEQYQEGLKL RCERFVEELE SYAKQAEEFY TFGDLQDVQR
760 770 780 790 800
YLKKAQVLNS KLDAAADKIE QFNAEEEAFG WIPSVYPQRK KIQDGLNPYL
810 820 830 840 850
RLYETAVEFS TKHRAWTEGP YHKVNPDQVE ADVGNYWRGL YKLEKAFHDS
860 870 880 890 900
PNALAMTKKV RARVEDFKQY IPLVQVICNP GLRPRHWEAM SAIVGYPLQP
910 920 930 940 950
SDDSTVFSFI DMNLEPFLDR FEGISEAASK EYSLEKSMDK MMTEWEAMEF
960 970 980 990 1000
VIHPYRESGT FILSAVDDIQ MLLDDHIIKT QTMRGSPFIK PYEKQMREWE
1010 1020 1030 1040 1050
GKLLLLQEIL DEWLKVQATW LYLEPIFSSP DIMSQMPEEG RRFTAVDKTW
1060 1070 1080 1090 1100
RDVMKMVVQN KHVLAVVTIE RMLERMKKSN ELLELILKGL NEYLEKKRLF
1110 1120 1130 1140 1150
FPRFFFLSND ELLEILSETK DPTRVQPHLK KCFEGIARVE FTETLDITHM
1160 1170 1180 1190 1200
KSSEGEVVEL VDTISTTKAR GQVEKWLVEL ERIMIKSIHK VIGDAITAYT
1210 1220 1230 1240 1250
KNARINWVRD WPGQTVLCVS QTFWTVEVQV AIPMGHKALE DYLGKCNHQI
1260 1270 1280 1290 1300
DDIVTLVRGK LSKQNRVTLG ALVVLDVHAR DVLANLVKKR ISDDTDFEWL
1310 1320 1330 1340 1350
SQLRYYWHEN NLETKMINAG LRYGYEYLGN SPRMVLAPFC DYCFLTLFGA
1360 1370 1380 1390 1400
LHLHLGGAPE GPAGTGKTET TKDLAKAVAK QCVVFNCSDG LDYLALGKFF
1410 1420 1430 1440 1450
KGLLSCGAWA CFDEFNRIDL EVLSVVAQQI LTIQIGINSG TELLVFEGTE
1460 1470 1480 1490 1500
LKLDPTCAVF ITMNPGYAGR SELPDNLKAL FRTVAMMVPD YAMIAEIVLY
1510 1520 1530 1540 1550
SCGFVTARPL SIKIVATYRL CSEQLSSQHH YDYGMRAVKS VLTAAGNLKL
1560 1570 1580 1590 1600
KYPNENEEIL LLRSIIDVNL PKFLSHDLPL FEGITSDLFP GVKLPKPDYN
1610 1620 1630 1640 1650
DLLAAIRENC HSMNLQMTNF FSEKILQIYE MMIVRHGFMI VGEPFGGKTS
1660 1670 1680 1690 1700
AYRVLAGALG DICEKGLMEE NKVQITVLNP KSVTMGQLYG QFDLVSHEWS
1710 1720 1730 1740 1750
DGILAVSFRA FAASSTPDRK WLIFDGPVDA VWIENMNTVL DDNKKLCLMS
1760 1770 1780 1790 1800
GEIIQMSPQM NLIFEPMDLE VASPATVSRC GMIYMEPQML GWRPLMVSWI
1810 1820 1830 1840 1850
NTLPQSVSII QKEFIEGLFD RMVPLSVEFI RRHTKELSPT SDTNLVRSLM
1860 1870 1880 1890 1900
NLIDCFMDDF ADENKQKERN DRENFSLLEG IFLFSLIWSV GASCTADDRI
1910 1920 1930 1940 1950
KYNKILRELM EGPISDLTRN KFKLLSGTEQ TSSKALTVPF PEKGTIYDYQ
1960 1970 1980 1990 2000
FIPEGLGRWD QWIKKLADTP PIPKDVQFNE IIVPTLDTVR YSALMSLLTT
2010 2020 2030 2040 2050
HQKPSIFVGP TGTGKSVYII NFLLNQLNKD IYKPLIVNFS AQTTAAQTQN
2060 2070 2080 2090 2100
IIMSKLDKRR KGVFGPPLGK RMIVFVDDVN MPAREVYGAQ PPIELLRQWL
2110 2120 2130 2140 2150
DHWNWYDLKD CSMIKLVDIQ IMCAMGPPGG GRNPITPRYM RHFNIITINE
2160 2170 2180 2190 2200
FSDKSMFTIF SRILTWHLRT CYKFPDDFLD LTTQIVNGTM TLYKDAMKNL
2210 2220 2230 2240 2250
LPTPAKSHYL FNLRDFSRVI QGVCLSRPET AENKEAIKRL WVHEVLRVYY
2260 2270 2280 2290 2300
DRLLDNADRS WLVNYIQEIL RNYMQEDFHD LFKNLDFDND GIVEEDDLRS
2310 2320 2330 2340 2350
LMFCDFHDPK REDFGYREIP NVDALRVIVE GHLDEYNNMS KKPMNLVLFR
2360 2370 2380 2390 2400
FAIEHISRIS RILKQPRSHA LLVGVGGSGR QSVTRLAAHM ADYSLFQVEI
2410 2420 2430 2440 2450
SKGYGSHEWH EDLKVILRKC AEGDMQGVFL FTDTQIKRES FLEDVNNLLN
2460 2470 2480 2490 2500
AGEVPNLFAL DEKQEICEKM RQLDRQRDKT KQTDGSPIAL FNMFIDRCRN
2510 2520 2530 2540 2550
QLHVVLAMSP IGDAFRIRLR KFPALVNCCT IDWFQSWPED ALEAVASRFL
2560 2570 2580 2590 2600
EDIEMSEEIR EGCIDMCKSF HTSTINLSTT FHNELQRYNY VTPTSYLELI
2610 2620 2630 2640 2650
STFKLLLEKK RNEVMKMKRR YEVGLDKLDS ASSQVATMQG ELEALHPQLK
2660 2670 2680 2690 2700
VASRQVDDMM IMIEKESIEV AKTEKIVKAD ETVANDQAMA AKAIKDECDA
2710 2720 2730 2740 2750
DLAEALPILE SALAALDTLT AQDITVVKSM KSPPAGVKLV MEAICILKGI
2760 2770 2780 2790 2800
KADKIPDPTG SGKKIEDFWG PAKRLLGDIR FLQSLHEYDK DNIPPAYMNI
2810 2820 2830 2840 2850
IRKSYIPNPD FVPEKIRNAS TAAEGLCKWV IAMDSYDKVA KIVAPKKIKL
2860 2870 2880 2890 2900
AAAEGELRIA MEGLRKKQAA LREVQDKLAK LQDTLELNKQ KKADLENQVD
2910 2920 2930 2940 2950
LCSKKLERAE QLIGGLGGEK TRWSNSALEL GHLYVNLTGD ILISSGVVAY
2960 2970 2980 2990 3000
LGAFTSNYRQ HQTKEWSHSC KERDIPCSDD YSLMGTLGEA VTIRAWNIAG
3010 3020 3030 3040 3050
LPSDLFSIDN GIIIMNARRW PLMIDPQGQA NKWIKNMEKT NSLQLIKLSD
3060 3070 3080 3090 3100
PDYVRTLENC IQFGTPVLLE NVGEELDPIL EPLLLKQTFK QGGSTCIRLG
3110 3120 3130 3140 3150
DSTIEYAPDF RFYITTKLRN PHYLPETSVK VTLLNFMITP EGMQDQLLGI
3160 3170 3180 3190 3200
VVARERPDLE EEKQALILQG AENKRQLKEI EDKILEVLSS SEGNILEDET
3210 3220 3230 3240 3250
AIKILSSSKA LANEISQKQE VAEETEKKID NTRMGYRPIA VHSSILFFSI
3260 3270 3280 3290 3300
ADLANIEPMY QYSLTWFINL FILSIENSEK SDILSQRLHI LRDHFTYSLY
3310 3320 3330 3340 3350
VNICRSLFEK DKMLFSFCLT VNLLIHENAI NKAEWRFLLT GGIGLDNPYT
3360 3370 3380 3390 3400
NPCTWLPQKS WDEICRLDEL HAFKTIRREF MRLKEGWKKV YDSMEPHHEI
3410 3420 3430 3440 3450
FPEEWENKAN DFQRMLIIRC LRPDKVIPML QEFIIKKLGR SFIEPPPFDL
3460 3470 3480 3490 3500
AKAFGDSNCC APLIFVLSPG ADPMNALLKF ADDQGYGGSK LSSLSLGQGQ
3510 3520 3530 3540 3550
GPIAMKMLEK AVKDGTWVVL QNCHLATSWM PTLEKVCEEL SPESTHPDFR
3560 3570 3580 3590 3600
IWLTSYPSPN FPVSVLQNGV KMTNEAPKGL RANIIRSYLM DPISDPEFFG
3610 3620 3630 3640 3650
SCRKPEEFKK LLYGLCFFHA LVQERRKFGP LGWNIPYEFN ETDLRISVQQ
3660 3670 3680 3690 3700
LHMFLNQYEE LPYDALRYMT GECNYGGRVT DDWDRRTLRS ILNKFFCTEL
3710 3720 3730 3740 3750
VENPQYKFDS SGIYFVPPSG DHKSYIEYTK TLPLIPDPEI FGMNANADIT
3760 3770 3780 3790 3800
KDQSETQLLF DNILLTQSRS SGSGAKSSDE VVNEVAGDIL GKLPNNFDIE
3810 3820 3830 3840 3850
SAMRRYPTTY TQSMNTVLVQ EMGRFNKLLI TIRESCINIQ KAIKGLVVMS
3860 3870 3880 3890 3900
TELEEVVSSI LNVKIPGMWM GKSYPSLKPL GSYVNDFLAR LKFLQQWYEV
3910 3920 3930 3940 3950
GPPPVFWLSG FFFTQAFLTG AQQNYARKFT IPIDLLGFDY EVMDDKEYKN
3960 3970 3980 3990 4000
APEDGVYIHG LFLDGASWNR KTKKLAESHP KVLYDTVPVM WLKPCKKSDI
4010 4020 4030 4040 4050
PKRPSYVAPL YKTSERRGTL STTGHSTNFV IAMILPSDQP KEHWIGRGVA

LLCQLNS
Length:4,057
Mass (Da):464,557
Last modified:February 5, 2008 - v2
Checksum:iECFA19724BABCFD4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1449 – 14513TEL → NRT in BAA05506 (PubMed:7657712).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03068169 Genomic DNA. No translation available.
AABR03068266 Genomic DNA. No translation available.
AABR03068762 Genomic DNA. No translation available.
AABR03068958 Genomic DNA. No translation available.
AABR03068975 Genomic DNA. No translation available.
AABR03069173 Genomic DNA. No translation available.
AABR03069339 Genomic DNA. No translation available.
AABR03069471 Genomic DNA. No translation available.
AABR03070154 Genomic DNA. No translation available.
AABR03071231 Genomic DNA. No translation available.
AABR03071501 Genomic DNA. No translation available.
AABR03071646 Genomic DNA. No translation available.
AABR03071706 Genomic DNA. No translation available.
AABR03071857 Genomic DNA. No translation available.
AABR03072256 Genomic DNA. No translation available.
D26498 mRNA. Translation: BAA05506.1.
U32180 mRNA. Translation: AAC52363.1.
PIRiI70177.
UniGeneiRn.232718.

Genome annotation databases

UCSCiRGD:621798. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03068169 Genomic DNA. No translation available.
AABR03068266 Genomic DNA. No translation available.
AABR03068762 Genomic DNA. No translation available.
AABR03068958 Genomic DNA. No translation available.
AABR03068975 Genomic DNA. No translation available.
AABR03069173 Genomic DNA. No translation available.
AABR03069339 Genomic DNA. No translation available.
AABR03069471 Genomic DNA. No translation available.
AABR03070154 Genomic DNA. No translation available.
AABR03071231 Genomic DNA. No translation available.
AABR03071501 Genomic DNA. No translation available.
AABR03071646 Genomic DNA. No translation available.
AABR03071706 Genomic DNA. No translation available.
AABR03071857 Genomic DNA. No translation available.
AABR03072256 Genomic DNA. No translation available.
D26498 mRNA. Translation: BAA05506.1.
U32180 mRNA. Translation: AAC52363.1.
PIRiI70177.
UniGeneiRn.232718.

3D structure databases

ProteinModelPortaliQ63170.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016465.

Proteomic databases

PaxDbiQ63170.
PRIDEiQ63170.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:621798. rat.

Organism-specific databases

RGDi621798. Dnah7.

Phylogenomic databases

eggNOGiKOG3595. Eukaryota.
COG5245. LUCA.
HOGENOMiHOG000237308.
HOVERGENiHBG107830.
InParanoidiQ63170.
PhylomeDBiQ63170.

Miscellaneous databases

NextBioi13955424.
PROiQ63170.

Family and domain databases

Gene3Di3.40.50.300. 5 hits.
InterProiIPR003593. AAA+_ATPase.
IPR026983. DHC_fam.
IPR026979. DNAH7.
IPR024743. Dynein_HC_stalk.
IPR024317. Dynein_heavy_chain_D4_dom.
IPR004273. Dynein_heavy_dom.
IPR013602. Dynein_heavy_dom-2.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10676. PTHR10676. 1 hit.
PTHR10676:SF138. PTHR10676:SF138. 1 hit.
PfamiPF12780. AAA_8. 1 hit.
PF08393. DHC_N2. 1 hit.
PF03028. Dynein_heavy. 1 hit.
PF12777. MT. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 5 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown Norway.
  2. "Identification and molecular evolution of new dynein-like protein sequences in rat brain."
    Tanaka Y., Zhang Z., Hirokawa N.
    J. Cell Sci. 108:1883-1893(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1369-1529, TISSUE SPECIFICITY.
    Strain: Wistar.
    Tissue: Brain.
  3. "Identification of seven rat axonemal dynein heavy chain genes: expression during ciliated cell differentiation."
    Andrews K.L., Nettesheim P., Asai D.J., Ostrowski L.E.
    Mol. Biol. Cell 7:71-79(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1372-1459, INDUCTION.
    Tissue: Trachea.

Entry informationi

Entry nameiDYH7_RAT
AccessioniPrimary (citable) accession number: Q63170
Secondary accession number(s): Q62821
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 5, 2008
Last modified: May 11, 2016
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.