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Q630W1 (MURA1_BACCZ) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1

EC=2.5.1.7
Alternative name(s):
Enoylpyruvate transferase 1
UDP-N-acetylglucosamine enolpyruvyl transferase 1
Short name=EPT 1
Gene names
Name:murA1
Synonyms:murA
Ordered Locus Names:BCE33L4987
OrganismBacillus cereus (strain ZK / E33L) [Complete proteome] [HAMAP]
Taxonomic identifier288681 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. HAMAP-Rule MF_00111

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine. HAMAP-Rule MF_00111

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00111

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00111.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 HAMAP-Rule MF_00111
PRO_0000231159

Sites

Active site1171Proton donor By similarity

Amino acid modifications

Modified residue11712-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity

Sequences

Sequence LengthMass (Da)Tools
Q630W1 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 0C2E9D8741A59344

FASTA43446,773
        10         20         30         40         50         60 
MEKIIVRGGK RLNGTVRVEG AKNAVLPIIA AALLASDGKN VLSEVPVLSD VYTINEVLRH 

        70         80         90        100        110        120 
LNAEVVFENN QVTIDASKEL NIEAPFEYVR KMRASVQVMG PLLARNGRAR IALPGGCAIG 

       130        140        150        160        170        180 
SRPIDQHLKG FEAMGAKVQV GNGFVEAYVE GELKGAKIYL DFPSVGATEN IMSAATLAKG 

       190        200        210        220        230        240 
TTILENAAKE PEIVDLANFL NAMGAKVRGA GTGTIRIEGV DKLYGANHSI IPDRIEAGTF 

       250        260        270        280        290        300 
MVAAAITGGD ILIENAVPEH LRSITAKMEE MGVKIIEENE GVRVIGPDKL KAVDIKTMPH 

       310        320        330        340        350        360 
PGFPTDMQSQ MMALLLQADG TSMITETVFE NRFMHVEEFR RMNADIKIEG RSVIMNGPNS 

       370        380        390        400        410        420 
LQGAEVGATD LRAAAALILA GLVSEGYTRV TELKHLDRGY VDFHKKLAAL GATIERVNEK 

       430 
VEEVKEQEVS DLHA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000001 Genomic DNA. Translation: AAU15293.1.
RefSeqYP_086556.1. NC_006274.1.

3D structure databases

ProteinModelPortalQ630W1.
SMRQ630W1. Positions 1-418.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING288681.BCZK4987.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU15293; AAU15293; BCE33L4987.
GeneID3022602.
KEGGbcz:BCZK4987.
PATRIC18893934. VBIBacCer95304_5275.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0766.
KOK00790.
OMAGYEHIED.
OrthoDBEOG68M4GK.
ProtClustDBPRK09369.

Enzyme and pathway databases

BioCycBCER288681:GHG7-5066-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00111. MurA.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. SSF55205. 1 hit.
TIGRFAMsTIGR01072. murA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURA1_BACCZ
AccessionPrimary (citable) accession number: Q630W1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 25, 2004
Last modified: February 19, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways