Unreviewed, UniProtKB/TrEMBL Q63094 (Q63094_RAT)

Names and origin

Protein names

Submitted name:
    Calcium/calmodulin-dependent protein kinase II, beta 3 isoform EMBL CAA58289.1

Gene names

Name:

Camk2b RGD 2262

Organism

Rattus norvegicus (Rat) EMBL CAA58289.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	589 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily.

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304V2 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305V3 Transferase
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Cellular component	calcium- and calmodulin-dependent protein kinase complex Traceable author statement. Source: UniProtKB
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW calmodulin binding Inferred from electronic annotation. Source: InterPro calmodulin-dependent protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q63094-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: C108DE09A1ACC4CB	FASTA	589	64,976
	10 20 30 40 50 60 MATTVTCTRF TDEYQLYEDI GKGAFSVVRR CVKLCTGHEY AAKIINTKKL SARDHQKLER 70 80 90 100 110 120 EARICRLLKH SNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI 130 140 150 160 170 180 LEAVLHCHQM GVVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY 190 200 210 220 230 240 LSPEVLRKEA YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT 250 260 270 280 290 300 VTPEAKNLIN QMLTINPAKR ITAHEALKHP WVCQRSTVAS MMHRQETVEC LKKFNARRKL 310 320 330 340 350 360 KGAILTTMLA TRNFSAAKSL LNKKADGVKP QTNSTKNSSA ITSPKGSLPP AALESSDSTN 370 380 390 400 410 420 TTIEDEDAKA PRISDILNSV RRGCGTPEAE GPLSVGPPPC LSPGLLGPLP TPSPRISDIL 430 440 450 460 470 480 NSVRRGSGTP EAEGLPPVGP PPCPSPTLPG PLPTPSRKQE IIKTTEQLIE AVNNGDFEAY 490 500 510 520 530 540 AKICDPGLTS FEPEALGNLV EGMDFHRFYF ENLLAKNSKP IHTTILNPHV HVIGEDAACI 550 560 570 580 AYIRLTQYID GQGRPRTSQS EETRVWHRPD GKWQNVHFHC SGAPVAPLQ

References

[1]	"A novel pancreatic beta-cell isoform of calcium/calmodulin-dependent protein kinase II (beta 3 isoform) contains a proline-rich tandem repeat in the association domain." Urquidi V., Ashcroft S.J. FEBS Lett. 358:23-26(1995) [PubMed: 7821422] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Pancreatic islets EMBL CAA58289.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X83375 mRNA. Translation: CAA58289.1.
IPI	IPI00326171.
PIR	S68470.
RefSeq	NP_001035813.1.
UniGene	Rn.9743
3D structure databases
HSSP	HSSP built from PDB template 1HKX based on UniProtKB P11798.
SMR	Q63094. Positions 11-301, 457-583.
ModBase	Search...
Protein-protein interaction databases
STRING	Q63094.
Genome annotation databases
Ensembl	ENSRNOT00000005441; ENSRNOP00000005441; ENSRNOG00000004005; Rattus norvegicus. [Genome view]
GeneID	24245.
KEGG	rno:24245.
UCSC	X83375. rat.
Organism-specific databases
CTD	24245.
Phylogenomic databases
HOVERGEN	Q63094.
PhylomeDB	Q63094.
Gene expression databases
ArrayExpress	Q63094.
Genevestigator	Q63094.
Family and domain databases
InterPro	IPR020636. Ca/CaM-dep_prot_kinase-like. IPR015742. Ca/CaM-dep_prot_kinase_2. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. IPR002290. Ser/Thr_prot_kinase_dom. [Graphical view]
PANTHER	PTHR22982. Ca/CaM-dep_prot_kinase-like. 1 hit. PTHR22982:SF64. CaMKII. 1 hit.
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	602737.

Entry information

Entry name

Q63094_RAT

Accession

Primary (citable) accession number: Q63094

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	February 9, 2010
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)