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Q62LN3 (ASTE_BURMA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Succinylglutamate desuccinylase

EC=3.5.1.96
Gene names
Name:astE
Ordered Locus Names:BMA0596
OrganismBurkholderia mallei (strain ATCC 23344) [Complete proteome] [HAMAP]
Taxonomic identifier243160 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transforms N(2)-succinylglutamate into succinate and glutamate By similarity. HAMAP-Rule MF_00767

Catalytic activity

N-succinyl-L-glutamate + H2O = succinate + L-glutamate. HAMAP-Rule MF_00767

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00767

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5. HAMAP-Rule MF_00767

Sequence similarities

Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 349349Succinylglutamate desuccinylase HAMAP-Rule MF_00767
PRO_0000257705

Sites

Active site2291 Potential
Metal binding701Zinc By similarity
Metal binding731Zinc By similarity
Metal binding1661Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q62LN3 [UniParc].

Last modified October 25, 2004. Version 1.
Checksum: 1D1F32BB7F0A1AF3

FASTA34937,622
        10         20         30         40         50         60 
MTSSADSGRD AAWLDDFLAL TLAGDAPPAE AGECAARAVR WRWLGDGLLR LEPADAAQRM 

        70         80         90        100        110        120 
QSVLVSAGVH GDETAPIELL STLVRDIARG ALPLRCRLLV ALGNPGAMRA GERYLDDDLN 

       130        140        150        160        170        180 
RLFGGRHAQL AASREAPRAA QLEAAAALFF STAGRARGAR WHIDMHTAIR TSVFEQFALL 

       190        200        210        220        230        240 
PHTGEPPTRT MFEWLGEAQI AAVLLHTTKG STFSHFTAQA CGALACTLEL GKVMPFGAND 

       250        260        270        280        290        300 
LSRFAPADAA VRRLVSGRRD APRGALPRAF TVVDQITKQS DALELFVAND VPNFTPFARG 

       310        320        330        340 
TLLARDGDYR YAVRHEQERI VFPNPSVKPG LRAGLLVIET TRDTHAALA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000010 Genomic DNA. Translation: AAU49282.1.
RefSeqYP_102386.1. NC_006348.1.

3D structure databases

ProteinModelPortalQ62LN3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243160.BMA0596.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU49282; AAU49282; BMA0596.
GeneID3088388.
KEGGbma:BMA0596.
PATRIC19116161. VBIBurMal55007_0612.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2988.
HOGENOMHOG000280300.
KOK05526.
OMATAPIEIC.
OrthoDBEOG613070.
ProtClustDBPRK05324.

Enzyme and pathway databases

UniPathwayUPA00185; UER00283.

Family and domain databases

HAMAPMF_00767. Arg_catab_AstE.
InterProIPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view]
PfamPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFPIRSF017020. AstE. 1 hit.
TIGRFAMsTIGR03242. arg_catab_astE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameASTE_BURMA
AccessionPrimary (citable) accession number: Q62LN3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 25, 2004
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways