Reviewed, UniProtKB/Swiss-Prot Q62H14 (ALLC2_BURMA)

Names and origin

Protein names

Recommended name:
    Probable allantoicase 2
    EC=3.5.3.4
Alternative name(s):
    Allantoate amidinohydrolase 2

Gene names

Name:	alc2
Ordered Locus Names:	BMA2460

Organism

Burkholderia mallei (Pseudomonas mallei) [Complete proteome] [HAMAP]

Taxonomic identifier

13373 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Allantoate + H2O = (S)-ureidoglycolate + urea. HAMAP MF_00813
Pathway	Nitrogen metabolism; (S)-allantoin degradation; (S)-ureidoglycolate from allantoate (aminidohydrolase route): step 1/1. HAMAP MF_00813
Sequence similarities	Belongs to the allantoicase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: HAMAP purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	allantoicase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 336	336	Probable allantoicase 2 HAMAP MF_00813		PRO_0000205918

Sequences

	Sequence		Length	Mass (Da)
	Q62H14-1 [UniParc]. Last modified October 25, 2004. Version 1. Checksum: 8433A0EEB79A5D93	FASTA	336	37,006
	10 20 30 40 50 60 MAAPILDPNA PAFTRRYMNL ADPRLGAKAL FASDEFFAPK ERMLDPEPAV FIPGKYDDHG 70 80 90 100 110 120 KWMDGWETRR KRTTGHDFCV VRLARPGVVY GVDLDTSHFT GNFPPAASID ACVSDADTPP 130 140 150 160 170 180 DDAVWETLVP ATTLAGNQHH YVDVSNPRAY THLRVNLYPD GGLARLRVYG QPQRDWSRAA 190 200 210 220 230 240 RGELVDLAAI ENGAYLVAAN NEHFGPASRM LMPGRGANMG DGWETRRRRE PGNDWAIVAL 250 260 270 280 290 300 ARPGVIRRVE VDTAHFKGNF PDRCSLQAAR VAGGTDASLV TQAMFWPMLL GEQPLGMDSV 310 320 330 HTFETQLAAL GPVTHVRLNI HPDGGVSRLR FWGELA

References

[1]

"Structural flexibility in the Burkholderia mallei genome." Nierman W.C., DeShazer D., Kim H.S., Tettelin H., Nelson K.E., Feldblyum T.V., Ulrich R.L., Ronning C.M., Brinkac L.M., Daugherty S.C., Davidsen T.D., DeBoy R.T., Dimitrov G., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Khouri H.M. , Kolonay J.F., Madupu R., Mohammoud Y., Nelson W.C., Radune D., Romero C.M., Sarria S., Selengut J., Shamblin C., Sullivan S.A., White O., Yu Y., Zafar N., Zhou L., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 101:14246-14251(2004) [PubMed: 15377793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 23344.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000010 Genomic DNA. Translation: AAU49694.1.
RefSeq	YP_104006.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3090505.
GenomeReviews	Gene locus BMA2460 in contig CP000010_GR.
KEGG	bma:BMA2460.
TIGR	BMA2460.
Phylogenomic databases
HOGENOM	Q62H14.
OMA	MANPILD.
Enzyme and pathway databases
BioCyc	BMAL243160:BMA_2460-MON.
BRENDA	3.5.3.4. 260531.
Family and domain databases
HAMAP	MF_00813. [Tree]
InterPro	IPR005164. Allantoicase. IPR015908. Allantoicase_region. [Graphical view]
PANTHER	PTHR12045. Allantoicase. 1 hit.
Pfam	PF03561. Allantoicase. 2 hits. [Graphical view]
PIRSF	PIRSF016516. Allantoicase. 1 hit.
TIGRFAMs	TIGR02961. allantoicase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLC2_BURMA

Accession

Primary (citable) accession number: Q62H14

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
Last sequence update:	October 25, 2004
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)