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Protein

Triple QxxK/R motif-containing protein

Gene

TRIQK

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May play a role in cell growth and maintenance of cell morphology.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Triple QxxK/R motif-containing protein
Alternative name(s):
Triple repetitive-sequence of QXXK/R protein homolog
Gene namesi
Name:TRIQK
Synonyms:C8orf83
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000205133.11.
HGNCiHGNC:27828. TRIQK.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei51 – 71HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000205133.
PharmGKBiPA164717477.

Polymorphism and mutation databases

BioMutaiTRIQK.
DMDMi74708352.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003406741 – 86Triple QxxK/R motif-containing proteinAdd BLAST86

Proteomic databases

EPDiQ629K1.
PaxDbiQ629K1.
PeptideAtlasiQ629K1.
PRIDEiQ629K1.
TopDownProteomicsiQ629K1.

PTM databases

PhosphoSitePlusiQ629K1.

Expressioni

Gene expression databases

BgeeiENSG00000205133.
CleanExiHS_C8orf83.
ExpressionAtlasiQ629K1. baseline and differential.
GenevisibleiQ629K1. HS.

Structurei

3D structure databases

ProteinModelPortaliQ629K1.
SMRiQ629K1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRIQK family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J2GZ. Eukaryota.
ENOG41121WQ. LUCA.
GeneTreeiENSGT00390000017350.
HOVERGENiHBG107675.
InParanoidiQ629K1.
OMAiCVYAFFY.
OrthoDBiEOG091G1BA1.
PhylomeDBiQ629K1.
TreeFamiTF328583.

Family and domain databases

InterProiView protein in InterPro
IPR024842. TRIQK.
PANTHERiPTHR20583. PTHR20583. 1 hit.
PfamiView protein in Pfam
PF15168. TRIQK. 1 hit.

Sequencei

Sequence statusi: Complete.

Q629K1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRKDAATIK LPVDQYRKQI GKQDYKKTKP ILRATKLKAE AKKTAIGIKE
60 70 80
VGLVLAAILA LLLAFYAFFY LRLTTDVDPD LDQDED
Length:86
Mass (Da):9,683
Last modified:October 25, 2004 - v1
Checksum:i34406C99BDDCD531
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ351291 mRNA. Translation: ABC84190.1.
CR749421 mRNA. Translation: CAH56121.1.
CH471060 Genomic DNA. Translation: EAW91691.1.
CCDSiCCDS55261.1.
RefSeqiNP_001165266.1. NM_001171795.1.
NP_001165267.1. NM_001171796.1.
NP_001165268.1. NM_001171797.1.
NP_001165269.1. NM_001171798.1.
NP_001165270.1. NM_001171799.1.
NP_001177964.1. NM_001191035.1.
NP_001177965.1. NM_001191036.1.
XP_016868836.1. XM_017013347.1.
XP_016868837.1. XM_017013348.1.
XP_016868838.1. XM_017013349.1.
XP_016868839.1. XM_017013350.1.
UniGeneiHs.440643.

Genome annotation databases

EnsembliENST00000378861; ENSP00000368138; ENSG00000205133.
ENST00000518748; ENSP00000430837; ENSG00000205133.
ENST00000519969; ENSP00000429381; ENSG00000205133.
ENST00000520430; ENSP00000428822; ENSG00000205133.
ENST00000520686; ENSP00000429822; ENSG00000205133.
ENST00000521617; ENSP00000430992; ENSG00000205133.
ENST00000521988; ENSP00000429517; ENSG00000205133.
ENST00000524107; ENSP00000429742; ENSG00000205133.
ENST00000537541; ENSP00000442030; ENSG00000205133.
GeneIDi286144.
KEGGihsa:286144.
UCSCiuc003yfk.5. human.

Similar proteinsi

Entry informationi

Entry nameiTRIQK_HUMAN
AccessioniPrimary (citable) accession number: Q629K1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: October 25, 2004
Last modified: September 27, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families