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Protein
Submitted name:

LAR receptor-linked tyrosine phosphatase

Gene

Ptprf

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101Phosphocysteine intermediatePROSITE-ProRule annotation1
Active sitei392Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphataseSAAS annotation, ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
LAR receptor-linked tyrosine phosphataseImported
Gene namesi
Name:PtprfImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3453. Ptprf.

PTM / Processingi

Proteomic databases

PaxDbiQ62917.

Structurei

3D structure databases

ProteinModelPortaliQ62917.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 160Tyrosine-protein phosphataseInterPro annotationAdd BLAST160
Domaini80 – 151TYR_PHOSPHATASE_2InterPro annotationAdd BLAST72
Domaini192 – 451Tyrosine-protein phosphataseInterPro annotationAdd BLAST260
Domaini369 – 442TYR_PHOSPHATASE_2InterPro annotationAdd BLAST74

Phylogenomic databases

eggNOGiKOG4228. Eukaryota.
COG5599. LUCA.
HOVERGENiHBG053758.

Family and domain databases

Gene3Di3.90.190.10. 2 hits.
InterProiView protein in InterPro
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
PfamiView protein in Pfam
PF00102. Y_phosphatase. 2 hits.
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiView protein in SMART
SM00194. PTPc. 2 hits.
SM00404. PTPc_motif. 2 hits.
SUPFAMiSSF52799. SSF52799. 2 hits.
PROSITEiView protein in PROSITE
PS00383. TYR_PHOSPHATASE_1. 2 hits.
PS50056. TYR_PHOSPHATASE_2. 2 hits.
PS50055. TYR_PHOSPHATASE_PTP. 2 hits.

Sequencei

Sequence statusi: Complete.

Q62917-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTRLEEKSR VKCDQYWPAR GTETYGLIQV TLVDTVELAT YTMRTFALHK
60 70 80 90 100
SGSSEKRELR QFQFMAWPDH GVPEYPTPIL AFLRRVKACN PLDAGPMVVH
110 120 130 140 150
CSAGVGRTGC FIVIDAMLER MKHEKTVDIY GHVTCMRSQR NYMVQTEDQY
160 170 180 190 200
VFIHEALLEA AMCGHTEVLA RNLYAHIQKL GQVPPGESVT AMELEFKLLA
210 220 230 240 250
NSKAHTSRFI SANLPCNKFK NRLVNIMPYE LTRVCLQPIR GVEGSDYINA
260 270 280 290 300
SFLDGYRQQK AYIATQGPLA ESTEDFWRML WEHNSTIIVM LTKLREMGRE
310 320 330 340 350
KCHQYWPAER SARYQYFVVD PMAEYNMPQY ILREFKVTDA RDGQSRTIRQ
360 370 380 390 400
FQFTDWPEQG VPKTGEGFID FIGQVHKTKE QFGQDGPITV HCSAGVGRTG
410 420 430 440 450
VFITLSIVLE RMRYEGVVDM FQTVKTLRTQ RPAMVQTEDQ YQLCYRAALE
460
YLGSFDHYAT
Length:460
Mass (Da):52,989
Last modified:November 1, 1996 - v1
Checksum:iB78C8E504F1260FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00477 mRNA. Translation: AAC04306.1.
PIRiA56493.
UniGeneiRn.11386.

Similar proteinsi

Entry informationi

Entry nameiQ62917_RAT
AccessioniPrimary (citable) accession number: Q62917
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)