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Protein

Probable calcium-binding mitochondrial carrier CBG00135

Gene

CBG00135

Organism
Caenorhabditis briggsae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Calcium-dependent mitochondrial solute carrier.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi83 – 941PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi150 – 1612PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandCalcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable calcium-binding mitochondrial carrier CBG00135
Gene namesi
ORF Names:CBG00135
OrganismiCaenorhabditis briggsae
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componentsi: Chromosome X, Unassembled WGS sequence

Organism-specific databases

WormBaseiCBG00135; CBP05663; WBGene00023609.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei249 – 266Helical; Name=1Sequence analysisAdd BLAST18
Transmembranei304 – 323Helical; Name=2Sequence analysisAdd BLAST20
Transmembranei349 – 362Helical; Name=3Sequence analysisAdd BLAST14
Transmembranei400 – 419Helical; Name=4Sequence analysisAdd BLAST20
Transmembranei442 – 459Helical; Name=5Sequence analysisAdd BLAST18
Transmembranei501 – 518Helical; Name=6Sequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002439231 – 532Probable calcium-binding mitochondrial carrier CBG00135Add BLAST532

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG00135.

Structurei

3D structure databases

ProteinModelPortaliQ628Z2.
SMRiQ628Z2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 106EF-hand 1PROSITE-ProRule annotationAdd BLAST37
Domaini107 – 136EF-hand 2PROSITE-ProRule annotationAdd BLAST30
Domaini137 – 172EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini173 – 208EF-hand 4PROSITE-ProRule annotationAdd BLAST36
Repeati243 – 329Solcar 1Add BLAST87
Repeati339 – 425Solcar 2Add BLAST87
Repeati436 – 526Solcar 3Add BLAST91

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0036. Eukaryota.
ENOG410XQ4P. LUCA.
HOGENOMiHOG000165728.
InParanoidiQ628Z2.
KOiK14684.
OMAiFWRHSTM.
OrthoDBiEOG091G0C8S.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom_sf.
PfamiView protein in Pfam
PF13499. EF-hand_7. 1 hit.
PF00153. Mito_carr. 3 hits.
PRINTSiPR00926. MITOCARRIER.
SMARTiView protein in SMART
SM00054. EFh. 3 hits.
SUPFAMiSSF103506. SSF103506. 1 hit.
SSF47473. SSF47473. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Q628Z2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTVETPLQ AGPLLKEKKQ ELIDIKNIQE HARTVQPFKA SKHQPLISGS
60 70 80 90 100
VSKEAAIATH AALHIDLTPE KEKKIREMYD RLDADNDGSI DIRDLTQALS
110 120 130 140 150
SQTPHIPATM APKLLAKMKR EDSDRVTYAD FTNYVIAHEA RLAEVFDQID
160 170 180 190 200
SNRDGEVDVS EIKSYCKEMG VNLDDHKALS IVKKMDQSGS SSVNLNEFQD
210 220 230 240 250
FMLLYPSTDM REMVDFWRHN LIIDIGEDGQ VPEDFTPQEL QSGVWWRHLV
260 270 280 290 300
AGGVAGAMSR TCTAPFDRIK VYLQVNSTKT NKLGVVSCVH LLHAEGGLKS
310 320 330 340 350
FWRGNGINVI KIAPESAMKF MSYDQIKRWI QEYKGGAELT TYERLFAGSS
360 370 380 390 400
AGAISQTAIY PMEVMKTRLA LRRTGQLDRG MIHFAHKMYD KEGIRCFYKG
410 420 430 440 450
YLPNLLGIIP YAGIDLTVYE TLKSCYTQYY TEHTEPGVLA LLACGTCSST
460 470 480 490 500
CGQLASYPLA LVRTRLQARA ISPKNSSQPD TMIGQFKHIL QNEGFTGLYR
510 520 530
GITPNFMKVI PAVSISYVVY EKVRKQLGAT MS
Length:532
Mass (Da):59,572
Last modified:November 23, 2004 - v1
Checksum:iE48D870AEBD6E85B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601409 Genomic DNA. Translation: CAP21634.1.
RefSeqiXP_002645256.1. XM_002645210.1.

Genome annotation databases

EnsemblMetazoaiCBG00135; CBG00135; WBGene00023609.
GeneIDi8587254.
KEGGicbr:CBG00135.

Similar proteinsi

Entry informationi

Entry nameiCMC3_CAEBR
AccessioniPrimary (citable) accession number: Q628Z2
Secondary accession number(s): A8WMD0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 23, 2004
Last modified: November 22, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families