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Protein
Submitted name:

5-hydroxytryptamine (Serotonin) receptor 2C, isoform CRA_b

Gene

Htr2c

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine (Serotonin) receptor 2C, isoform CRA_bImported
Submitted name:
Serotonin 5-HT2cImported
Gene namesi
Name:Htr2cImported
ORF Names:rCG_23163Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2848. Htr2c.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei49 – 76HelicalSequence analysisAdd BLAST28
Transmembranei148 – 168HelicalSequence analysisAdd BLAST21
Transmembranei188 – 207HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060345.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 204G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST204

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000240378.
HOVERGENiHBG107487.
KOiK04157.

Family and domain databases

InterProiView protein in InterPro
IPR000377. 5HT2C_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR24247:SF169. PTHR24247:SF169. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00517. 5HT2CRECEPTR.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q62842-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCYFQLRPSC TSAPYRWTGV SVPIPVIGLR DESKVFVNNT TCVLNDPNFV
60 70 80 90 100
LIGSFVAFFI PLTIMVITYF LTIYVLRRQT LMLLRGHTEE ELANMSLNFL
110 120 130 140 150
NCCCKKNGGE EENAPNPNPD QKPRRKKKEK RPRGTMQAIN NEKKASKVLG
160 170 180 190 200
IVFFVFLIMW CPFFITNILS VLCGKACNQK LMEKLLNVFV WIGYVCSGIN
210 220 230 240 250
PLVYTLFNKI YRRAFSKYLR CDYKPDKKPP VRQIPRVAAT ALSGRELNVN
260 270 280 290
IYRHTNERVA RKANDPEPGI EMQVENLELP VNPSNVVSER ISSV
Length:294
Mass (Da):33,653
Last modified:November 1, 1996 - v1
Checksum:i6CC5803421AC1562
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U35315 mRNA. Translation: AAB37757.1.
CH474047 Genomic DNA. Translation: EDL85171.1.
RefSeqiNP_036897.2. NM_012765.3.
UniGeneiRn.9935.

Genome annotation databases

GeneIDi25187.
KEGGirno:25187.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U35315 mRNA. Translation: AAB37757.1.
CH474047 Genomic DNA. Translation: EDL85171.1.
RefSeqiNP_036897.2. NM_012765.3.
UniGeneiRn.9935.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060345.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi25187.
KEGGirno:25187.

Organism-specific databases

CTDi3358.
RGDi2848. Htr2c.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000240378.
HOVERGENiHBG107487.
KOiK04157.

Family and domain databases

InterProiView protein in InterPro
IPR000377. 5HT2C_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR24247:SF169. PTHR24247:SF169. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00517. 5HT2CRECEPTR.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ62842_RAT
AccessioniPrimary (citable) accession number: Q62842
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 10, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.