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Q62522

- ZPBP1_MOUSE

UniProt

Q62522 - ZPBP1_MOUSE

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Protein

Zona pellucida-binding protein 1

Gene

Zpbp

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

May be implicated in gamete interaction during fertilization.By similarity

GO - Biological processi

  1. acrosome assembly Source: MGI
  2. binding of sperm to zona pellucida Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Zona pellucida-binding protein 1
Alternative name(s):
Sp38
Gene namesi
Name:Zpbp
Synonyms:Zpbp1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:1855701. Zpbp.

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. acrosomal vesicle Source: MGI
  2. cell body Source: MGI
  3. extracellular region Source: UniProtKB-KW
  4. nucleus Source: Ensembl
  5. zona pellucida receptor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 4444Sequence AnalysisAdd
BLAST
Chaini45 – 350306Zona pellucida-binding protein 1PRO_0000041599Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi113 – 1131N-linked (GlcNAc...)Sequence Analysis
Glycosylationi186 – 1861N-linked (GlcNAc...)Sequence Analysis
Glycosylationi339 – 3391N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ62522.
PRIDEiQ62522.

PTM databases

PhosphoSiteiQ62522.

Expressioni

Gene expression databases

BgeeiQ62522.
CleanExiMM_ZPBP.
ExpressionAtlasiQ62522. baseline and differential.
GenevestigatoriQ62522.

Structurei

3D structure databases

ProteinModelPortaliQ62522.
SMRiQ62522. Positions 97-144.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG41092.
HOVERGENiHBG106672.
InParanoidiQ62522.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR013783. Ig-like_fold.
IPR010857. Sp38-bd.
[Graphical view]
PANTHERiPTHR15443. PTHR15443. 1 hit.
PfamiPF07354. Sp38. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q62522-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEALAPGRAP RGRRRAGASG SVLSPLSLAA VLLCALLRAP PAVGHLARLP
60 70 80 90 100
RSIHLTQDSL KIVGSTHFPV SVYVMLHQKS PHVLCVTQRL RNTELVDPSF
110 120 130 140 150
QWHGPKGKLV SENTTAQVTS TGSLIFQSFE ETMSGVYTCF LEYKPTVEES
160 170 180 190 200
IKNLQLKYIV YAYREPRFYY QFTARYHAAP CNSIYNISFE KKLLQILSKL
210 220 230 240 250
VLDLSCEISL IKSECHRVKM QRAGLQNELF FTFSVASIDT EKGSKPCTDH
260 270 280 290 300
SCEASKRLSK AKNLIERFFI QQVEVLGKRA EPLPEIYYIE GTLQMVWVNR
310 320 330 340 350
CFPGYGINVL KHPKCPECCV VCSPGSFNPR DGTHCLQCNN SLVYGAKTCM
Length:350
Mass (Da):39,232
Last modified:October 11, 2004 - v2
Checksum:iCABD14DAE1C76EE8
GO

Sequence cautioni

The sequence BAA04494.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D17569 mRNA. Translation: BAA04494.1. Different initiation.
AK006274 mRNA. Translation: BAB24497.1.
AK018889 mRNA. Translation: BAB31476.1.
AK018921 mRNA. Translation: BAB31483.1.
AK029541 mRNA. Translation: BAC26504.1.
RefSeqiNP_056600.1. NM_015785.2.
UniGeneiMm.9500.

Genome annotation databases

GeneIDi53604.
KEGGimmu:53604.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D17569 mRNA. Translation: BAA04494.1 . Different initiation.
AK006274 mRNA. Translation: BAB24497.1 .
AK018889 mRNA. Translation: BAB31476.1 .
AK018921 mRNA. Translation: BAB31483.1 .
AK029541 mRNA. Translation: BAC26504.1 .
RefSeqi NP_056600.1. NM_015785.2.
UniGenei Mm.9500.

3D structure databases

ProteinModelPortali Q62522.
SMRi Q62522. Positions 97-144.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q62522.

Proteomic databases

PaxDbi Q62522.
PRIDEi Q62522.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 53604.
KEGGi mmu:53604.

Organism-specific databases

CTDi 11055.
MGIi MGI:1855701. Zpbp.

Phylogenomic databases

eggNOGi NOG41092.
HOVERGENi HBG106672.
InParanoidi Q62522.

Miscellaneous databases

ChiTaRSi Zpbp. mouse.
NextBioi 310293.
PROi Q62522.
SOURCEi Search...

Gene expression databases

Bgeei Q62522.
CleanExi MM_ZPBP.
ExpressionAtlasi Q62522. baseline and differential.
Genevestigatori Q62522.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR013783. Ig-like_fold.
IPR010857. Sp38-bd.
[Graphical view ]
PANTHERi PTHR15443. PTHR15443. 1 hit.
Pfami PF07354. Sp38. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Expression of the gene encoding zona-pellucida-binding protein, sp38, during spermatogenesis."
    Baba T., Mori E., Mori T., Kashiwabara S., Tanaka K.
    Submitted (SEP-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: ddY.
    Tissue: Testis.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 144-350.
    Strain: C57BL/6J.
    Tissue: Testis.

Entry informationi

Entry nameiZPBP1_MOUSE
AccessioniPrimary (citable) accession number: Q62522
Secondary accession number(s): Q9CR97
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: November 26, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3