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Q62522

- ZPBP1_MOUSE

UniProt

Q62522 - ZPBP1_MOUSE

Protein

Zona pellucida-binding protein 1

Gene

Zpbp

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 2 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    May be implicated in gamete interaction during fertilization.By similarity

    GO - Biological processi

    1. acrosome assembly Source: MGI
    2. binding of sperm to zona pellucida Source: MGI

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Zona pellucida-binding protein 1
    Alternative name(s):
    Sp38
    Gene namesi
    Name:Zpbp
    Synonyms:Zpbp1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    Organism-specific databases

    MGIiMGI:1855701. Zpbp.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. acrosomal vesicle Source: MGI
    2. cell body Source: MGI
    3. extracellular region Source: UniProtKB-SubCell
    4. zona pellucida receptor complex Source: MGI

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 4444Sequence AnalysisAdd
    BLAST
    Chaini45 – 350306Zona pellucida-binding protein 1PRO_0000041599Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi113 – 1131N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi186 – 1861N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi339 – 3391N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ62522.
    PRIDEiQ62522.

    PTM databases

    PhosphoSiteiQ62522.

    Expressioni

    Gene expression databases

    BgeeiQ62522.
    CleanExiMM_ZPBP.
    GenevestigatoriQ62522.

    Structurei

    3D structure databases

    ProteinModelPortaliQ62522.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG41092.
    HOVERGENiHBG106672.
    InParanoidiQ62522.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR013783. Ig-like_fold.
    IPR010857. Sp38-bd.
    [Graphical view]
    PANTHERiPTHR15443. PTHR15443. 1 hit.
    PfamiPF07354. Sp38. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q62522-1 [UniParc]FASTAAdd to Basket

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    MEALAPGRAP RGRRRAGASG SVLSPLSLAA VLLCALLRAP PAVGHLARLP    50
    RSIHLTQDSL KIVGSTHFPV SVYVMLHQKS PHVLCVTQRL RNTELVDPSF 100
    QWHGPKGKLV SENTTAQVTS TGSLIFQSFE ETMSGVYTCF LEYKPTVEES 150
    IKNLQLKYIV YAYREPRFYY QFTARYHAAP CNSIYNISFE KKLLQILSKL 200
    VLDLSCEISL IKSECHRVKM QRAGLQNELF FTFSVASIDT EKGSKPCTDH 250
    SCEASKRLSK AKNLIERFFI QQVEVLGKRA EPLPEIYYIE GTLQMVWVNR 300
    CFPGYGINVL KHPKCPECCV VCSPGSFNPR DGTHCLQCNN SLVYGAKTCM 350
    Length:350
    Mass (Da):39,232
    Last modified:October 11, 2004 - v2
    Checksum:iCABD14DAE1C76EE8
    GO

    Sequence cautioni

    The sequence BAA04494.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D17569 mRNA. Translation: BAA04494.1. Different initiation.
    AK006274 mRNA. Translation: BAB24497.1.
    AK018889 mRNA. Translation: BAB31476.1.
    AK018921 mRNA. Translation: BAB31483.1.
    AK029541 mRNA. Translation: BAC26504.1.
    RefSeqiNP_056600.1. NM_015785.2.
    UniGeneiMm.9500.

    Genome annotation databases

    GeneIDi53604.
    KEGGimmu:53604.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D17569 mRNA. Translation: BAA04494.1 . Different initiation.
    AK006274 mRNA. Translation: BAB24497.1 .
    AK018889 mRNA. Translation: BAB31476.1 .
    AK018921 mRNA. Translation: BAB31483.1 .
    AK029541 mRNA. Translation: BAC26504.1 .
    RefSeqi NP_056600.1. NM_015785.2.
    UniGenei Mm.9500.

    3D structure databases

    ProteinModelPortali Q62522.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q62522.

    Proteomic databases

    PaxDbi Q62522.
    PRIDEi Q62522.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 53604.
    KEGGi mmu:53604.

    Organism-specific databases

    CTDi 11055.
    MGIi MGI:1855701. Zpbp.

    Phylogenomic databases

    eggNOGi NOG41092.
    HOVERGENi HBG106672.
    InParanoidi Q62522.

    Miscellaneous databases

    NextBioi 310293.
    PROi Q62522.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q62522.
    CleanExi MM_ZPBP.
    Genevestigatori Q62522.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR013783. Ig-like_fold.
    IPR010857. Sp38-bd.
    [Graphical view ]
    PANTHERi PTHR15443. PTHR15443. 1 hit.
    Pfami PF07354. Sp38. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of the gene encoding zona-pellucida-binding protein, sp38, during spermatogenesis."
      Baba T., Mori E., Mori T., Kashiwabara S., Tanaka K.
      Submitted (SEP-1993) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: ddY.
      Tissue: Testis.
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 144-350.
      Strain: C57BL/6J.
      Tissue: Testis.

    Entry informationi

    Entry nameiZPBP1_MOUSE
    AccessioniPrimary (citable) accession number: Q62522
    Secondary accession number(s): Q9CR97
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 86 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3