Q62522 (ZPBP1_MOUSE) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 78.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Zona pellucida-binding protein 1 Alternative name(s): Sp38 | ||||
| Gene names |
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| Organism | Mus musculus (Mouse) [Reference proteome] | ||||
| Taxonomic identifier | 10090 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus![]() |
Protein attributes
| Sequence length | 350 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | May be implicated in gamete interaction during fertilization By similarity. |
| Subcellular location | Secreted Potential. |
| Sequence similarities | Belongs to the zona pellucida-binding protein Sp38 family. |
| Sequence caution | The sequence BAA04494.1 differs from that shown. Reason: Erroneous initiation. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Secreted |
| Domain | Signal |
| PTM | Glycoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | acrosome assembly Inferred from mutant phenotype PubMed 17664285. Source: MGI binding of sperm to zona pellucidaInferred from direct assay PubMed 21880732. Source: MGI |
| Cellular_component | acrosomal vesicle Inferred from direct assay PubMed 17664285. Source: MGI extracellular regionInferred from electronic annotation. Source: UniProtKB-SubCell sperm partInferred from direct assay PubMed 21880732. Source: MGI zona pellucida receptor complexInferred from direct assay PubMed 21880732. Source: MGI |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 44 | 44 | Potential | ||||||
| Chain | 45 – 350 | 306 | Zona pellucida-binding protein 1 | PRO_0000041599 | |||||
Amino acid modifications | |||||||||
| Glycosylation | 113 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 186 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 339 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Expression of the gene encoding zona-pellucida-binding protein, sp38, during spermatogenesis." Baba T., Mori E., Mori T., Kashiwabara S., Tanaka K. Submitted (SEP-1993) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: ddY. Tissue: Testis. |
| [2] | "The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. Hayashizaki Y.Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 144-350. Strain: C57BL/6J. Tissue: Testis. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | D17569 mRNA. Translation: BAA04494.1. Different initiation. AK006274 mRNA. Translation: BAB24497.1. AK018889 mRNA. Translation: BAB31476.1. AK018921 mRNA. Translation: BAB31483.1. AK029541 mRNA. Translation: BAC26504.1. |
| IPI | IPI00127150. |
| RefSeq | NP_056600.1. NM_015785.2. |
| UniGene | Mm.9500. |
3D structure databases | |
| SMR | Q62522. Positions 97-144. |
| ModBase | Search... |
PTM databases | |
| PhosphoSite | Q62522. |
Proteomic databases | |
| PaxDb | Q62522. |
| PRIDE | Q62522. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 53604. |
| KEGG | mmu:53604. |
Organism-specific databases | |
| CTD | 11055. |
| MGI | MGI:1855701. Zpbp. |
Phylogenomic databases | |
| eggNOG | NOG41092. |
| HOVERGEN | HBG106672. |
| InParanoid | Q62522. |
| OrthoDB | EOG4ZW5BG. |
Gene expression databases | |
| ArrayExpress | Q62522. |
| Bgee | Q62522. |
| CleanEx | MM_ZPBP. |
| Genevestigator | Q62522. |
| GermOnline | ENSMUSG00000020193. Mus musculus. |
Family and domain databases | |
| Gene3D | 2.60.40.10. 1 hit. |
| InterPro | IPR013783. Ig-like_fold. IPR010857. Sp38-bd. [Graphical view] |
| PANTHER | PTHR15443. PTHR15443. 1 hit. |
| Pfam | PF07354. Sp38. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 310293. |
| SOURCE | Search... |
Entry information
| Entry name | ZPBP1_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q62522 Secondary accession number(s): Q9CR97 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| MGD cross-references Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |

Clusters with
