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Protein

T-cell acute lymphocytic leukemia protein 2 homolog

Gene

Tal2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • midbrain development Source: MGI
  • multicellular organism growth Source: MGI
  • post-embryonic development Source: MGI
  • thalamus development Source: MGI
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
T-cell acute lymphocytic leukemia protein 2 homolog
Short name:
TAL-2
Gene namesi
Name:Tal2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:99540. Tal2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001274571 – 108T-cell acute lymphocytic leukemia protein 2 homologAdd BLAST108

Proteomic databases

PaxDbiQ62282.
PRIDEiQ62282.

PTM databases

iPTMnetiQ62282.
PhosphoSitePlusiQ62282.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028417.
CleanExiMM_TAL2.
ExpressionAtlasiQ62282. baseline and differential.
GenevisibleiQ62282. MM.

Interactioni

Protein-protein interaction databases

BioGridi203963. 3 interactors.
STRINGi10090.ENSMUSP00000030124.

Structurei

3D structure databases

ProteinModelPortaliQ62282.
SMRiQ62282.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 54bHLHPROSITE-ProRule annotationAdd BLAST53

Sequence similaritiesi

Contains 1 bHLH (basic helix-loop-helix) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4029. Eukaryota.
ENOG411227D. LUCA.
GeneTreeiENSGT00760000119097.
HOGENOMiHOG000129920.
HOVERGENiHBG004515.
InParanoidiQ62282.
KOiK09068.
OMAiLFPQGSH.
OrthoDBiEOG091G0ESI.
PhylomeDBiQ62282.
TreeFamiTF315153.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q62282-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRKIFTNTR ERWRQQSVNN AFAKLRKLIP THPPDKKLSK NETLRLAMRY
60 70 80 90 100
INFLVKVLGE QSLHQTGVAA QGNILGLFPP KTRLPDEDDR TLLNDYRVPS

PGPSHGAP
Length:108
Mass (Da):12,315
Last modified:November 1, 1996 - v1
Checksum:i11B8A7711520AF13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M81077 Genomic DNA. Translation: AAA40162.1.
AK018448 mRNA. Translation: BAB31216.1.
CCDSiCCDS18192.1.
RefSeqiNP_033343.1. NM_009317.3.
UniGeneiMm.56955.

Genome annotation databases

EnsembliENSMUST00000030124; ENSMUSP00000030124; ENSMUSG00000028417.
GeneIDi21350.
KEGGimmu:21350.
UCSCiuc008sxg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M81077 Genomic DNA. Translation: AAA40162.1.
AK018448 mRNA. Translation: BAB31216.1.
CCDSiCCDS18192.1.
RefSeqiNP_033343.1. NM_009317.3.
UniGeneiMm.56955.

3D structure databases

ProteinModelPortaliQ62282.
SMRiQ62282.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi203963. 3 interactors.
STRINGi10090.ENSMUSP00000030124.

PTM databases

iPTMnetiQ62282.
PhosphoSitePlusiQ62282.

Proteomic databases

PaxDbiQ62282.
PRIDEiQ62282.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030124; ENSMUSP00000030124; ENSMUSG00000028417.
GeneIDi21350.
KEGGimmu:21350.
UCSCiuc008sxg.1. mouse.

Organism-specific databases

CTDi6887.
MGIiMGI:99540. Tal2.

Phylogenomic databases

eggNOGiKOG4029. Eukaryota.
ENOG411227D. LUCA.
GeneTreeiENSGT00760000119097.
HOGENOMiHOG000129920.
HOVERGENiHBG004515.
InParanoidiQ62282.
KOiK09068.
OMAiLFPQGSH.
OrthoDBiEOG091G0ESI.
PhylomeDBiQ62282.
TreeFamiTF315153.

Miscellaneous databases

PROiQ62282.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028417.
CleanExiMM_TAL2.
ExpressionAtlasiQ62282. baseline and differential.
GenevisibleiQ62282. MM.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTAL2_MOUSE
AccessioniPrimary (citable) accession number: Q62282
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.