Q62240 (KDM5D_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Lysine-specific demethylase 5D
EC=1.14.11.-

Alternative name(s):
Histocompatibility Y antigen
Short name=H-Y
Histone demethylase JARID1D
Jumonji/ARID domain-containing protein 1D
Protein SmcY

Gene names

Name:	Kdm5d
Synonyms:	Hya, Jarid1d, Smcy

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1548 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis By similarity. Ref.5 Ref.6
Cofactor	Ascorbate By similarity. Binds 1 Fe2+ ion per subunit By similarity.
Subunit structure	Interacts with PCGF6 and MSH5 By similarity.
Subcellular location	Nucleus By similarity.
Domain	The JmjC domain is required for enzymatic activity By similarity.
Miscellaneous	KDM5D encodes an H-Y epitope that is defined by the octamer peptide TENSGKDI; since no similar peptide was found in KDM5C, it is presumably the genetic basis for the antigenic difference between males and females that contributes toward a tissue transplant rejection response.
Sequence similarities	Belongs to the JARID1 histone demethylase family. Contains 1 ARID domain. Contains 1 JmjC domain. Contains 1 JmjN domain. Contains 2 PHD-type zinc fingers.

Ontologies

Keywords
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Repeat Zinc-finger
Ligand	Iron Metal-binding Zinc
Molecular function	Chromatin regulator Dioxygenase Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro histone demethylase activity (H3-K4 specific) Inferred from electronic annotation. Source: Compara oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q62240-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q62240-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-398: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q62240-3)

The sequence of this isoform differs from the canonical sequence as follows:
     583-586: VRTN → SIWK
     587-1548: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q62240-4)

The sequence of this isoform differs from the canonical sequence as follows:
     687-691: GITEA → LSLQA
     692-1548: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1548	1548	Lysine-specific demethylase 5D		PRO_0000200589
Regions
	Domain	14 – 55	42	JmjN
	Domain	79 – 169	91	ARID
	Domain	467 – 633	167	JmjC
	Zinc finger	325 – 371	47	PHD-type 1
	Zinc finger	1182 – 1243	62	PHD-type 2
Sites
	Metal binding	513	1	Iron; catalytic By similarity
	Metal binding	516	1	Iron; catalytic By similarity
	Metal binding	601	1	Iron; catalytic By similarity
Natural variations
	Alternative sequence	1 – 398	398	Missing in isoform 2.		VSP_026412
	Alternative sequence	583 – 586	4	VRTN → SIWK in isoform 3.		VSP_026413
	Alternative sequence	587 – 1548	962	Missing in isoform 3.		VSP_026414
	Alternative sequence	687 – 691	5	GITEA → LSLQA in isoform 4.		VSP_026415
	Alternative sequence	692 – 1548	857	Missing in isoform 4.		VSP_026416
Experimental info
	Sequence conflict	160 – 162	3	IIY → SFT in CAA82760. Ref.4
	Sequence conflict	167	1	F → S in CAA82760. Ref.4
	Sequence conflict	215	1	R → K in CAA82760. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified October 24, 2001. Version 2. Checksum: 44AAB94708EA4A02	FASTA	1,548	177,018
	10 20 30 40 50 60 MKPGSDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 70 80 90 100 110 120 DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERKIL DLYSLNKIVM 130 140 150 160 170 180 EEGGYEAICK DRRWARVAQR LNYPSGKNIG SLLRSHYERI IYPYEIFQSG ANLVQCNTDP 190 200 210 220 230 240 FDSEERDKEY KPHSIPLRQS VQPSKFSCYS RRGKRLQPEP EPTEEDIEKN PELKKLQIYG 250 260 270 280 290 300 AGPKMIGLGL KAKEKTLRKK DSKQPDKEEV TCPATIVVKG EASEFGKVTS AFSDKNLNHS 310 320 330 340 350 360 FEPCMKMTMQ LRNNHSSTQF MNSYVCRICS RGDEVDKFLL CDGCSDNYHI FCLLPPLSEV 370 380 390 400 410 420 PKGVWRCPKC ILAECKSPPE AFGFEQATQE YTLQSFGEMA DSFKADYFNM PVHMVPTEVV 430 440 450 460 470 480 EKEFWRLVSS IEEDVTVEYG ADIHSKEFGS GFPVNNSKWD LSPEEKEYAA CGWNLNVMPV 490 500 510 520 530 540 LDQSVLCHIN ADISGMKVPW LYVGMVFSAF CWHIEDHWSY SINYLHWGEP KTWYGVPSLA 550 560 570 580 590 600 AEHLEDVMKR LTPELFDSQP DLLHQLVTLM NPNTLMSHGV PVVRTNQCAG EFVITFPRAY 610 620 630 640 650 660 HSGFNQGYNF AEAVNFCTAD WLPVGRQCIE HYRRLRRYCV FSHEELICKM AAFPEKLDLN 670 680 690 700 710 720 LAVAVHKEMF IMVQEERRLR KTLLEKGITE AEREAFELLP DDERQCIKCK TTCFLSALAC 730 740 750 760 770 780 YDCPDSLVCL SHINDLCKCS RNRQYLRYRY TLDELPAMLQ KLKIRAESFD NWANKVQAAL 790 800 810 820 830 840 EVEDGRKRSF EELRALESEA RDRRFPNSEL LQRLKKCLTE AEACISQVLG LISNSEDRLQ 850 860 870 880 890 900 TPQITLTELQ LLLKQMGTLP CTMHQIDEVK DVLQQVESYQ IETREALTSL PYSLEILQSL 910 920 930 940 950 960 MEKGQQLRVE VPEAHQLEEL LEQAQWLDQV KQALAPSGQR HSLVIMKKLL VMGTKVASSP 970 980 990 1000 1010 1020 SVNKARAELQ ELLTIAECWE EKAHFCLKAS QKHSPATLEV IIREAENIPV YLPNIQSLKE 1030 1040 1050 1060 1070 1080 ALTKAQAWIA DVNEIQNGDH YPCLDDLEGL VAVGRDLPVE LEELRQLENQ VLTAHSWKEK 1090 1100 1110 1120 1130 1140 ASKTFLKKNS CYTLLEVLCP CADAGSVSTK RSRWIEKEMG LYKYDTELLG LSAQDLRDPG 1150 1160 1170 1180 1190 1200 SVIMAFKEGE EKEKEGILHL RHINSAKPSP MSSSMNASAT SICICGQVCA GVESLQCDLC 1210 1220 1230 1240 1250 1260 HDWFHGQCVT VPHLLSSVRA SHTSSQLLAW WEWDTKFLCP LCMRSRRPRL ETILSLLVGL 1270 1280 1290 1300 1310 1320 QRLSVRLPEG EALQCLTERA IGWQGRARQA LASEDVTALL KQLEKSRQQL QDELRHKKPP 1330 1340 1350 1360 1370 1380 TLPSGFAFDC LTENSGKDIL KEEEELVLNE ERIKSSEKIV PKESSCKGDK ELLPSLLSQL 1390 1400 1410 1420 1430 1440 TGPVLELPEA TRAPLEELMM EGDLLEVTLD ENYSIWQLLQ AGQNPNLERI HTLLELEKPE 1450 1460 1470 1480 1490 1500 NPGNWSEEQT PERRRQRRQK VVLSRKGEDF TQKELESKRV KSSRIKPKEE KFQKPILGDN 1510 1520 1530 1540 VLYTHHTEHT NILKEHINSV QGKDPSPSSS FPSLTPLLHL SYFHQQKL
	Isoform 2 [UniParc]. Checksum: 2920BEB66B2E98CF	FASTA	1,150	131,396
	10 20 30 40 50 60 MADSFKADYF NMPVHMVPTE VVEKEFWRLV SSIEEDVTVE YGADIHSKEF GSGFPVNNSK 70 80 90 100 110 120 WDLSPEEKEY AACGWNLNVM PVLDQSVLCH INADISGMKV PWLYVGMVFS AFCWHIEDHW 130 140 150 160 170 180 SYSINYLHWG EPKTWYGVPS LAAEHLEDVM KRLTPELFDS QPDLLHQLVT LMNPNTLMSH 190 200 210 220 230 240 GVPVVRTNQC AGEFVITFPR AYHSGFNQGY NFAEAVNFCT ADWLPVGRQC IEHYRRLRRY 250 260 270 280 290 300 CVFSHEELIC KMAAFPEKLD LNLAVAVHKE MFIMVQEERR LRKTLLEKGI TEAEREAFEL 310 320 330 340 350 360 LPDDERQCIK CKTTCFLSAL ACYDCPDSLV CLSHINDLCK CSRNRQYLRY RYTLDELPAM 370 380 390 400 410 420 LQKLKIRAES FDNWANKVQA ALEVEDGRKR SFEELRALES EARDRRFPNS ELLQRLKKCL 430 440 450 460 470 480 TEAEACISQV LGLISNSEDR LQTPQITLTE LQLLLKQMGT LPCTMHQIDE VKDVLQQVES 490 500 510 520 530 540 YQIETREALT SLPYSLEILQ SLMEKGQQLR VEVPEAHQLE ELLEQAQWLD QVKQALAPSG 550 560 570 580 590 600 QRHSLVIMKK LLVMGTKVAS SPSVNKARAE LQELLTIAEC WEEKAHFCLK ASQKHSPATL 610 620 630 640 650 660 EVIIREAENI PVYLPNIQSL KEALTKAQAW IADVNEIQNG DHYPCLDDLE GLVAVGRDLP 670 680 690 700 710 720 VELEELRQLE NQVLTAHSWK EKASKTFLKK NSCYTLLEVL CPCADAGSVS TKRSRWIEKE 730 740 750 760 770 780 MGLYKYDTEL LGLSAQDLRD PGSVIMAFKE GEEKEKEGIL HLRHINSAKP SPMSSSMNAS 790 800 810 820 830 840 ATSICICGQV CAGVESLQCD LCHDWFHGQC VTVPHLLSSV RASHTSSQLL AWWEWDTKFL 850 860 870 880 890 900 CPLCMRSRRP RLETILSLLV GLQRLSVRLP EGEALQCLTE RAIGWQGRAR QALASEDVTA 910 920 930 940 950 960 LLKQLEKSRQ QLQDELRHKK PPTLPSGFAF DCLTENSGKD ILKEEEELVL NEERIKSSEK 970 980 990 1000 1010 1020 IVPKESSCKG DKELLPSLLS QLTGPVLELP EATRAPLEEL MMEGDLLEVT LDENYSIWQL 1030 1040 1050 1060 1070 1080 LQAGQNPNLE RIHTLLELEK PENPGNWSEE QTPERRRQRR QKVVLSRKGE DFTQKELESK 1090 1100 1110 1120 1130 1140 RVKSSRIKPK EEKFQKPILG DNVLYTHHTE HTNILKEHIN SVQGKDPSPS SSFPSLTPLL 1150 HLSYFHQQKL
	Isoform 3 [UniParc]. Checksum: A5764F58390D60F8	FASTA	586	67,244
	10 20 30 40 50 60 MKPGSDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 70 80 90 100 110 120 DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERKIL DLYSLNKIVM 130 140 150 160 170 180 EEGGYEAICK DRRWARVAQR LNYPSGKNIG SLLRSHYERI IYPYEIFQSG ANLVQCNTDP 190 200 210 220 230 240 FDSEERDKEY KPHSIPLRQS VQPSKFSCYS RRGKRLQPEP EPTEEDIEKN PELKKLQIYG 250 260 270 280 290 300 AGPKMIGLGL KAKEKTLRKK DSKQPDKEEV TCPATIVVKG EASEFGKVTS AFSDKNLNHS 310 320 330 340 350 360 FEPCMKMTMQ LRNNHSSTQF MNSYVCRICS RGDEVDKFLL CDGCSDNYHI FCLLPPLSEV 370 380 390 400 410 420 PKGVWRCPKC ILAECKSPPE AFGFEQATQE YTLQSFGEMA DSFKADYFNM PVHMVPTEVV 430 440 450 460 470 480 EKEFWRLVSS IEEDVTVEYG ADIHSKEFGS GFPVNNSKWD LSPEEKEYAA CGWNLNVMPV 490 500 510 520 530 540 LDQSVLCHIN ADISGMKVPW LYVGMVFSAF CWHIEDHWSY SINYLHWGEP KTWYGVPSLA 550 560 570 580 AEHLEDVMKR LTPELFDSQP DLLHQLVTLM NPNTLMSHGV PVSIWK
	Isoform 4 [UniParc]. Checksum: 40681B920A8B54FE	FASTA	691	79,525
	10 20 30 40 50 60 MKPGSDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 70 80 90 100 110 120 DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERKIL DLYSLNKIVM 130 140 150 160 170 180 EEGGYEAICK DRRWARVAQR LNYPSGKNIG SLLRSHYERI IYPYEIFQSG ANLVQCNTDP 190 200 210 220 230 240 FDSEERDKEY KPHSIPLRQS VQPSKFSCYS RRGKRLQPEP EPTEEDIEKN PELKKLQIYG 250 260 270 280 290 300 AGPKMIGLGL KAKEKTLRKK DSKQPDKEEV TCPATIVVKG EASEFGKVTS AFSDKNLNHS 310 320 330 340 350 360 FEPCMKMTMQ LRNNHSSTQF MNSYVCRICS RGDEVDKFLL CDGCSDNYHI FCLLPPLSEV 370 380 390 400 410 420 PKGVWRCPKC ILAECKSPPE AFGFEQATQE YTLQSFGEMA DSFKADYFNM PVHMVPTEVV 430 440 450 460 470 480 EKEFWRLVSS IEEDVTVEYG ADIHSKEFGS GFPVNNSKWD LSPEEKEYAA CGWNLNVMPV 490 500 510 520 530 540 LDQSVLCHIN ADISGMKVPW LYVGMVFSAF CWHIEDHWSY SINYLHWGEP KTWYGVPSLA 550 560 570 580 590 600 AEHLEDVMKR LTPELFDSQP DLLHQLVTLM NPNTLMSHGV PVVRTNQCAG EFVITFPRAY 610 620 630 640 650 660 HSGFNQGYNF AEAVNFCTAD WLPVGRQCIE HYRRLRRYCV FSHEELICKM AAFPEKLDLN 670 680 690 LAVAVHKEMF IMVQEERRLR KTLLEKLSLQ A

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx." Agulnik A.I., Longepied G., Ty M.T., Bishop C.E., Mitchell M.J. Mamm. Genome 10:926-929(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Strain: 129/SvJ.
[2]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4). Strain: C57BL/6J. Tissue: Head.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Strain: C57BL/6. Tissue: Brain.
[4]	"A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens." Agulnik A.I., Mitchell M.J., Lerner J.L., Woods D.R., Bishop C.E. Hum. Mol. Genet. 3:873-878(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 23-1548 (ISOFORM 3). Strain: BALB/c. Tissue: Testis.
[5]	"Identification of a mouse male-specific transplantation antigen, H-Y." Scott D.M., Ehrmann I.E., Ellis P.S., Bishop C.E., Agulnik A.I., Simpson E., Mitchell M.J. Nature 376:695-698(1995) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[6]	"Spermatogenic failure in male mice lacking H-Y antigen." Burgoyne P.S., Levy E.R., McLaren A. Nature 320:170-172(1986) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF127244 mRNA. Translation: AAD53048.1. AK140971 mRNA. Translation: BAE24534.1. BC059077 mRNA. Translation: AAH59077.1. Z29652 mRNA. Translation: CAA82760.1.
IPI	IPI00123375. IPI00848809. IPI00848997. IPI00850747.
PIR	I48776.
RefSeq	NP_035549.1. NM_011419.3.
UniGene	Mm.262676.
3D structure databases
ProteinModelPortal	Q62240.
SMR	Q62240. Positions 79-171, 319-659, 1182-1244.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000061095.
PTM databases
PhosphoSite	Q62240.
Proteomic databases
PaxDb	Q62240.
PRIDE	Q62240.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000055032; ENSMUSP00000061095; ENSMUSG00000056673.
GeneID	20592.
KEGG	mmu:20592.
UCSC	uc009uyz.1. mouse. uc009uzb.1. mouse.
Organism-specific databases
CTD	8284.
MGI	MGI:99780. Kdm5d.
Phylogenomic databases
eggNOG	NOG327026.
GeneTree	ENSGT00530000063118.
HOGENOM	HOG000290719.
InParanoid	Q62240.
KO	K11446.
OrthoDB	EOG4894KP.
Gene expression databases
Bgee	Q62240.
Genevestigator	Q62240.
GermOnline	ENSMUSG00000056673. Mus musculus.
Family and domain databases
Gene3D	1.10.150.60. 1 hit. 3.30.40.10. 2 hits.
InterPro	IPR001606. ARID/BRIGHT_DNA-bd. IPR003347. JmjC_dom. IPR013637. Lys_sp_deMease_like_dom. IPR003349. TF_JmjN. IPR019786. Zinc_finger_PHD-type_CS. IPR004198. Znf_C5HC2. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR019787. Znf_PHD-finger. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Pfam	PF01388. ARID. 1 hit. PF02373. JmjC. 1 hit. PF02375. JmjN. 1 hit. PF00628. PHD. 1 hit. PF08429. PLU-1. 1 hit. PF02928. zf-C5HC2. 1 hit. [Graphical view]
SMART	SM00501. BRIGHT. 1 hit. SM00558. JmjC. 1 hit. SM00545. JmjN. 1 hit. SM00249. PHD. 2 hits. [Graphical view]
SUPFAM	SSF46774. ARID. 1 hit. SSF57903. FYVE_PHD_ZnF. 2 hits.
PROSITE	PS51011. ARID. 1 hit. PS51184. JMJC. 1 hit. PS51183. JMJN. 1 hit. PS01359. ZF_PHD_1. 2 hits. PS50016. ZF_PHD_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	298905.
SOURCE	Search...

Entry information

Entry name

KDM5D_MOUSE

Accession

Primary (citable) accession number: Q62240
Secondary accession number(s): Q3US03 , Q6PCX3, Q9QVR9, Q9R040

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 24, 2001
Last sequence update:	October 24, 2001
Last modified:	May 1, 2013
This is version 107 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program