##gff-version 3
Q62137	UniProtKB	Chain	1	1100	.	.	.	ID=PRO_0000088116;Note=Tyrosine-protein kinase JAK3	
Q62137	UniProtKB	Domain	24	353	.	.	.	Note=FERM;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00084	
Q62137	UniProtKB	Domain	372	472	.	.	.	Note=SH2%3B atypical	
Q62137	UniProtKB	Domain	517	777	.	.	.	Note=Protein kinase 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q62137	UniProtKB	Domain	818	1100	.	.	.	Note=Protein kinase 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q62137	UniProtKB	Region	1	223	.	.	.	Note=Interaction with cytokine/interferon/growth hormone receptors;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q62137	UniProtKB	Active site	945	945	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10028	
Q62137	UniProtKB	Binding site	824	832	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q62137	UniProtKB	Binding site	851	851	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q62137	UniProtKB	Modified residue	17	17	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
Q62137	UniProtKB	Modified residue	781	781	.	.	.	Note=Phosphotyrosine%3B by autocatalysis;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P52333	
Q62137	UniProtKB	Modified residue	900	900	.	.	.	Note=Phosphotyrosine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P52333	
Q62137	UniProtKB	Modified residue	935	935	.	.	.	Note=Phosphotyrosine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P52333	
Q62137	UniProtKB	Modified residue	976	976	.	.	.	Note=Phosphotyrosine%3B by autocatalysis;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P52333	
Q62137	UniProtKB	Modified residue	977	977	.	.	.	Note=Phosphotyrosine%3B by autocatalysis;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P52333	
Q62137	UniProtKB	Alternative sequence	284	284	.	.	.	ID=VSP_027575;Note=In isoform 2. E->EVLGLGLRSGVRGEAWRLVKKPVRTIRKVASPGRADCTTGQGGGVNLKVGPGMELPQGLTWGVTRRVRLDRGRGRTEGDSMDWISGHDPTRPVFSPLTSSPPPHKWRWEGGRRGGCAGSRSVIPWLLSLFLFFFFNGFARQGFSYSSGCPGTHFVRPGWPRTQKSACLCLSSAVIKGRVPLRRYCLSFLPQ;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:7518579;Dbxref=PMID:7518579	
Q62137	UniProtKB	Alternative sequence	379	379	.	.	.	ID=VSP_027576;Note=In isoform 2. L->LGASWGQQWGWGWAARTVLGWTWLLSWPRL;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:7518579;Dbxref=PMID:7518579	
Q62137	UniProtKB	Mutagenesis	853	853	.	.	.	Note=Loss of activity. L->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:8605329;Dbxref=PMID:8605329	
Q62137	UniProtKB	Sequence conflict	62	62	.	.	.	Note=G->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	277	277	.	.	.	Note=S->P;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	281	283	.	.	.	Note=GDQ->ND;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	301	301	.	.	.	Note=K->N;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	362	362	.	.	.	Note=P->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	371	372	.	.	.	Note=EL->DV;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	390	390	.	.	.	Note=G->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	454	454	.	.	.	Note=Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	467	467	.	.	.	Note=N->Y;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	490	490	.	.	.	Note=T->N;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	518	519	.	.	.	Note=EW->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	535	535	.	.	.	Note=R->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	699	699	.	.	.	Note=C->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	716	717	.	.	.	Note=SG->QR;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	800	800	.	.	.	Note=G->VA;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	826	826	.	.	.	Note=K->N;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	841	841	.	.	.	Note=Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	857	857	.	.	.	Note=G->V;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	909	909	.	.	.	Note=F->L;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	915	916	.	.	.	Note=AR->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	916	916	.	.	.	Note=R->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	1032	1032	.	.	.	Note=R->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	1074	1074	.	.	.	Note=W->V;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	1077	1077	.	.	.	Note=S->E;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	1085	1085	.	.	.	Note=G->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	1093	1093	.	.	.	Note=A->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q62137	UniProtKB	Sequence conflict	1093	1093	.	.	.	Note=A->P;Ontology_term=ECO:0000305;evidence=ECO:0000305