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Protein
Submitted name:

Myelin proteolipid

Gene

Plp1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Myelin proteolipidImported
Gene namesi
Name:Plp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97623. Plp1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 4029HelicalSequence analysisAdd
BLAST
Transmembranei60 – 8829HelicalSequence analysisAdd
BLAST
Transmembranei152 – 17827HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ62079.
PeptideAtlasiQ62079.
PRIDEiQ62079.

Interactioni

Protein-protein interaction databases

IntActiQ62079. 4 interactions.
STRINGi10090.ENSMUSP00000033800.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4800. Eukaryota.
ENOG4110EPW. LUCA.
HOGENOMiHOG000231338.
HOVERGENiHBG000096.

Family and domain databases

InterProiIPR001614. Myelin_PLP.
IPR018237. Myelin_PLP_CS.
[Graphical view]
PANTHERiPTHR11683. PTHR11683. 2 hits.
PfamiPF01275. Myelin_PLP. 1 hit.
[Graphical view]
PRINTSiPR00214. MYELINPLP.
SMARTiSM00002. PLP. 1 hit.
[Graphical view]
PROSITEiPS00575. MYELIN_PLP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q62079-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLECCARC LVGAPFASLV ATGLCFFGVA LFCGCGHEAL TGTEKLIETY
60 70 80 90 100
FSKNYQDYEY LINVIHAFQC VIYGTASFFF LYGALLLAEG FYTTGAVRQI
110 120 130 140 150
FGDYKTTICG KGLSATVTGG QKGRGYRGQH QAHSLERVCH CLGKWLGHPD
160 170 180 190 200
KFVGITYALT VVWLLVFACS AVPVYIYFNT WTTCQSIAFP SKTSASIGSL
210 220 230 240
CADARMYVPN DLPPVYCCVC GCCGHTSFPA HLHDCCHLQL RRP
Length:243
Mass (Da):26,567
Last modified:November 1, 1996 - v1
Checksum:i0006E01F4EA9C446
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20752 mRNA. Translation: AAA39956.1.
UniGeneiMm.1268.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20752 mRNA. Translation: AAA39956.1.
UniGeneiMm.1268.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ62079. 4 interactions.
STRINGi10090.ENSMUSP00000033800.

Proteomic databases

PaxDbiQ62079.
PeptideAtlasiQ62079.
PRIDEiQ62079.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:97623. Plp1.

Phylogenomic databases

eggNOGiKOG4800. Eukaryota.
ENOG4110EPW. LUCA.
HOGENOMiHOG000231338.
HOVERGENiHBG000096.

Miscellaneous databases

ChiTaRSiPlp1. mouse.
SOURCEiSearch...

Family and domain databases

InterProiIPR001614. Myelin_PLP.
IPR018237. Myelin_PLP_CS.
[Graphical view]
PANTHERiPTHR11683. PTHR11683. 2 hits.
PfamiPF01275. Myelin_PLP. 1 hit.
[Graphical view]
PRINTSiPR00214. MYELINPLP.
SMARTiSM00002. PLP. 1 hit.
[Graphical view]
PROSITEiPS00575. MYELIN_PLP_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing."
    Nave K.-A., Lai C., Bloom F.E., Milner R.J.
    Proc. Natl. Acad. Sci. U.S.A. 83:9264-9268(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: jimpyImported.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ62079_MOUSE
AccessioniPrimary (citable) accession number: Q62079
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.