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Protein

Serine/threonine-protein phosphatase Pgam5, mitochondrial

Gene

pgam-5

Organism
Caenorhabditis briggsae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase Pgam5, mitochondrial (EC:3.1.3.16)
Alternative name(s):
Phosphoglycerate mutase family member 5 homolog
Gene namesi
Name:pgam-5
ORF Names:CBG13006
OrganismiCaenorhabditis briggsae
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000008549 Componentsi: Chromosome II, Unassembled WGS sequence

Organism-specific databases

WormBaseiCBG13006; CBP36220; WBGene00033850; Cbr-pgam-5.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2317HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 283283Serine/threonine-protein phosphatase Pgam5, mitochondrialPRO_0000288788Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ61CA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG71348.
HOGENOMiHOG000261217.
InParanoidiQ61CA3.
OMAiEIIVCHA.
OrthoDBiEOG7966H1.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.

Sequencei

Sequence statusi: Complete.

Q61CA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSKILMYGL PSAAVAVGTA LLNEDNRNTI FRKAFAFTQN HTPKSFDEHF
60 70 80 90 100
PRGEWDKNWD FRDPTSLVDK SKWEKADEVG KKKLLEECKA TASRNIFLIR
110 120 130 140 150
HGQYHLDREQ KHLTELGREQ AELLGKRLAN SDIKFTNMTM STMTRATETA
160 170 180 190 200
NIILKHLPGD LPKSSSSLIE EGPPYPPVPD HKTWRPLDPE FYTEAARIES
210 220 230 240 250
AFRKLIHRAP PSQKEDSYEL IVCHANVIRY FICRALQFPP EGWLRMSLGN
260 270 280
CSITWLVIRP KGHVSIRSVG DIGHLTPNKI SFT
Length:283
Mass (Da):32,352
Last modified:September 22, 2009 - v2
Checksum:i13294946775B4DB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600938 Genomic DNA. Translation: CAP31880.2.

Genome annotation databases

EnsemblMetazoaiCBG13006; CBG13006; CBG13006.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600938 Genomic DNA. Translation: CAP31880.2.

3D structure databases

ProteinModelPortaliQ61CA3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCBG13006; CBG13006; CBG13006.

Organism-specific databases

WormBaseiCBG13006; CBP36220; WBGene00033850; Cbr-pgam-5.

Phylogenomic databases

eggNOGiNOG71348.
HOGENOMiHOG000261217.
InParanoidiQ61CA3.
OMAiEIIVCHA.
OrthoDBiEOG7966H1.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16.

Entry informationi

Entry nameiPGAM5_CAEBR
AccessioniPrimary (citable) accession number: Q61CA3
Secondary accession number(s): A8XGV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: September 22, 2009
Last modified: January 7, 2015
This is version 39 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.