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Q61C05 (CNEP1_CAEBR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
CTD nuclear envelope phosphatase 1 homolog

EC=3.1.3.16
Alternative name(s):
Serine/threonine-protein phosphatase dullard homolog
Small C-terminal domain phosphatase-like phosphatase 2
Gene names
Name:scpl-2
ORF Names:CBG13136
OrganismCaenorhabditis briggsae [Reference proteome]
Taxonomic identifier6238 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length246 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the dullard family.

Contains 1 FCP1 homology domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 246246CTD nuclear envelope phosphatase 1 homolog
PRO_0000297974

Regions

Transmembrane3 – 2321Helical; Potential
Domain53 – 220168FCP1 homology

Sequences

Sequence LengthMass (Da)Tools
Q61C05 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 793ED6CE6513D471

FASTA24628,419
        10         20         30         40         50         60 
MTSFAQTVFY VLAGLFNVFL LYFRKTNRAY CKYQVVKYHS NIPMSPLTTH RLLTVKRKIL 

        70         80         90        100        110        120 
VLDLDETLIH SHHDGVLRQT VKPGTPSDFT IRVVIDRHPV KFSVHERPHV DYFLTVVSQW 

       130        140        150        160        170        180 
YELVVFTASM EVYGSSVADK LDRGRGILKR RYFRQHCTME VGGYTKDLSA IHPDLSSICI 

       190        200        210        220        230        240 
LDNSPGAYRK FPHNAIPIPS WFSDPNDTCL LNLLPFLDAL RFTSDVRSVL SRNMQVLPET 


QTVQYY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HE601401 Genomic DNA. Translation: CAP31978.3.
RefSeqXP_002646742.1. XM_002646696.1.

3D structure databases

ProteinModelPortalQ61C05.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6238.CBG13136.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaCBG13136; CBG13136; CBG13136.
GeneID8588741.
KEGGcbr:CBG13136.

Organism-specific databases

CTD8588741.
WormBaseCBG13136; CBP03219; WBGene00033948; Cbr-scpl-2.

Phylogenomic databases

eggNOGCOG5190.
KOK17617.
OMALLGIRTF.
OrthoDBEOG7MKW6W.

Family and domain databases

Gene3D3.40.50.1000. 1 hit.
InterProIPR011948. Dullard_phosphatase.
IPR023214. HAD-like_dom.
IPR004274. NIF.
[Graphical view]
PfamPF03031. NIF. 1 hit.
[Graphical view]
SMARTSM00577. CPDc. 1 hit.
[Graphical view]
SUPFAMSSF56784. SSF56784. 1 hit.
TIGRFAMsTIGR02251. HIF-SF_euk. 1 hit.
PROSITEPS50969. FCP1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCNEP1_CAEBR
AccessionPrimary (citable) accession number: Q61C05
Secondary accession number(s): A8XH54
Entry history
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: November 23, 2004
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families