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Q619N4 (ACP1_CAEBR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative acid phosphatase 1

EC=3.1.3.2
Gene names
ORF Names:CBG14199
OrganismCaenorhabditis briggsae [Reference proteome]
Taxonomic identifier6238 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Subcellular location

Membrane; Single-pass type I membrane protein Potential.

Sequence similarities

Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal
Transmembrane
Transmembrane helix
   Molecular functionHydrolase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionacid phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 426408Putative acid phosphatase 1
PRO_0000248566

Regions

Topological domain19 – 388370Extracellular Potential
Transmembrane389 – 40921Helical; Potential
Topological domain410 – 42617Cytoplasmic Potential

Sites

Active site291Nucleophile By similarity
Active site2761Proton donor By similarity

Amino acid modifications

Glycosylation371N-linked (GlcNAc...) Potential
Glycosylation1451N-linked (GlcNAc...) Potential
Glycosylation3801N-linked (GlcNAc...) Potential
Disulfide bond133 ↔ 369 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q619N4 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 5CA7D6B37BF30CE5

FASTA42648,455
        10         20         30         40         50         60 
MRVLFYVFPF VIFALSQAQL ISVHVIFRHG ARAPVLNVTS EEAKSYFYRG LGQLTDVCIE 

        70         80         90        100        110        120 
QAKLIGKVLK DRYVNTFVDA RMLPTQLLFR SSPVERCLMT IQTVGNTMFV NSTPPVQTVA 

       130        140        150        160        170        180 
KPDDFLLVPK LDCAFQIDEW TNFFNLTEND KKQAKKNPWF ISEKALRRAT AASQTLQQRS 

       190        200        210        220        230        240 
DENLPALILE KDAGLAVPSW FNEEAYKESL TVFYKALAVM SSVGEYKSSK GIRVKTGLLL 

       250        260        270        280        290        300 
DKILNDIQEK VRCHEKNQKG HISCDRHKLQ VFSTHDLLIL PFLDALGIRE AALGEDLPPK 

       310        320        330        340        350        360 
FLSAIIIETM LLDDIPFVKV FYRGDPRDIT LRDMTGLVRN CPPNQALCPV NLFTSCCGEF 

       370        380        390        400        410        420 
ITADPRRECY EEKADQQLHN WTMTTVSWIL IGISAFLLII LIIMSYLAVR YKNRSVVTIK 


KVCLEN 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HE600983 Genomic DNA. Translation: CAP32804.3.
RefSeqXP_002644366.1. XM_002644320.1.

3D structure databases

ProteinModelPortalQ619N4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6238.CBG14199.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaCBG14199; CBG14199; CBG14199.
GeneID8586361.
KEGGcbr:CBG14199.

Organism-specific databases

CTD8586361.
WormBaseCBG14199; CBP03468; WBGene00034774.

Phylogenomic databases

eggNOGNOG306642.
HOGENOMHOG000115658.
OMAVERCLMT.
OrthoDBEOG7NSB64.

Family and domain databases

InterProIPR000560. His_Pase_superF_clade-2.
[Graphical view]
PfamPF00328. His_Phos_2. 1 hit.
[Graphical view]
PROSITEPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACP1_CAEBR
AccessionPrimary (citable) accession number: Q619N4
Secondary accession number(s): A8XJH9
Entry history
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: November 23, 2004
Last modified: April 16, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families