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Q619N4

- ACP1_CAEBR

UniProt

Q619N4 - ACP1_CAEBR

Protein

Putative acid phosphatase 1

Gene

CBG14199

Organism
Caenorhabditis briggsae
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei29 – 291NucleophileBy similarity
    Active sitei276 – 2761Proton donorBy similarity

    GO - Molecular functioni

    1. acid phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative acid phosphatase 1 (EC:3.1.3.2)
    Gene namesi
    ORF Names:CBG14199
    OrganismiCaenorhabditis briggsae
    Taxonomic identifieri6238 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000008549: Chromosome X, UP000008549: Unassembled WGS sequence

    Organism-specific databases

    WormBaseiCBG14199; CBP03468; WBGene00034774.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 426408Putative acid phosphatase 1PRO_0000248566Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi37 – 371N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi133 ↔ 369By similarity
    Glycosylationi145 – 1451N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi380 – 3801N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi6238.CBG14199.

    Structurei

    3D structure databases

    ProteinModelPortaliQ619N4.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini19 – 388370ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini410 – 42617CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei389 – 40921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histidine acid phosphatase family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG306642.
    HOGENOMiHOG000115658.
    OMAiVERCLMT.
    OrthoDBiEOG7NSB64.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    InterProiIPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view]
    PfamiPF00328. His_Phos_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF53254. SSF53254. 1 hit.
    PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q619N4-1 [UniParc]FASTAAdd to Basket

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    MRVLFYVFPF VIFALSQAQL ISVHVIFRHG ARAPVLNVTS EEAKSYFYRG    50
    LGQLTDVCIE QAKLIGKVLK DRYVNTFVDA RMLPTQLLFR SSPVERCLMT 100
    IQTVGNTMFV NSTPPVQTVA KPDDFLLVPK LDCAFQIDEW TNFFNLTEND 150
    KKQAKKNPWF ISEKALRRAT AASQTLQQRS DENLPALILE KDAGLAVPSW 200
    FNEEAYKESL TVFYKALAVM SSVGEYKSSK GIRVKTGLLL DKILNDIQEK 250
    VRCHEKNQKG HISCDRHKLQ VFSTHDLLIL PFLDALGIRE AALGEDLPPK 300
    FLSAIIIETM LLDDIPFVKV FYRGDPRDIT LRDMTGLVRN CPPNQALCPV 350
    NLFTSCCGEF ITADPRRECY EEKADQQLHN WTMTTVSWIL IGISAFLLII 400
    LIIMSYLAVR YKNRSVVTIK KVCLEN 426
    Length:426
    Mass (Da):48,455
    Last modified:November 23, 2004 - v1
    Checksum:i5CA7D6B37BF30CE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE600983 Genomic DNA. Translation: CAP32804.3.
    RefSeqiXP_002644366.1. XM_002644320.1.

    Genome annotation databases

    EnsemblMetazoaiCBG14199; CBG14199; CBG14199.
    GeneIDi8586361.
    KEGGicbr:CBG14199.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE600983 Genomic DNA. Translation: CAP32804.3 .
    RefSeqi XP_002644366.1. XM_002644320.1.

    3D structure databases

    ProteinModelPortali Q619N4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6238.CBG14199.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai CBG14199 ; CBG14199 ; CBG14199 .
    GeneIDi 8586361.
    KEGGi cbr:CBG14199.

    Organism-specific databases

    CTDi 8586361.
    WormBasei CBG14199 ; CBP03468 ; WBGene00034774 .

    Phylogenomic databases

    eggNOGi NOG306642.
    HOGENOMi HOG000115658.
    OMAi VERCLMT.
    OrthoDBi EOG7NSB64.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    InterProi IPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view ]
    Pfami PF00328. His_Phos_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53254. SSF53254. 1 hit.
    PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AF16.

    Entry informationi

    Entry nameiACP1_CAEBR
    AccessioniPrimary (citable) accession number: Q619N4
    Secondary accession number(s): A8XJH9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3