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Q619N4

- ACP1_CAEBR

UniProt

Q619N4 - ACP1_CAEBR

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Protein

Putative acid phosphatase 1

Gene

CBG14199

Organism
Caenorhabditis briggsae
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei29 – 291NucleophileBy similarity
Active sitei276 – 2761Proton donorBy similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative acid phosphatase 1 (EC:3.1.3.2)
Gene namesi
ORF Names:CBG14199
OrganismiCaenorhabditis briggsae
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000008549: Chromosome X, UP000008549: Unassembled WGS sequence

Organism-specific databases

WormBaseiCBG14199; CBP03468; WBGene00034774.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence AnalysisAdd
BLAST
Chaini19 – 426408Putative acid phosphatase 1PRO_0000248566Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi37 – 371N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi133 ↔ 369By similarity
Glycosylationi145 – 1451N-linked (GlcNAc...)Sequence Analysis
Glycosylationi380 – 3801N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG14199.

Structurei

3D structure databases

ProteinModelPortaliQ619N4.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini19 – 388370ExtracellularSequence AnalysisAdd
BLAST
Topological domaini410 – 42617CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei389 – 40921HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG306642.
HOGENOMiHOG000115658.
InParanoidiQ619N4.
OMAiVERCLMT.
OrthoDBiEOG7NSB64.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q619N4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRVLFYVFPF VIFALSQAQL ISVHVIFRHG ARAPVLNVTS EEAKSYFYRG
60 70 80 90 100
LGQLTDVCIE QAKLIGKVLK DRYVNTFVDA RMLPTQLLFR SSPVERCLMT
110 120 130 140 150
IQTVGNTMFV NSTPPVQTVA KPDDFLLVPK LDCAFQIDEW TNFFNLTEND
160 170 180 190 200
KKQAKKNPWF ISEKALRRAT AASQTLQQRS DENLPALILE KDAGLAVPSW
210 220 230 240 250
FNEEAYKESL TVFYKALAVM SSVGEYKSSK GIRVKTGLLL DKILNDIQEK
260 270 280 290 300
VRCHEKNQKG HISCDRHKLQ VFSTHDLLIL PFLDALGIRE AALGEDLPPK
310 320 330 340 350
FLSAIIIETM LLDDIPFVKV FYRGDPRDIT LRDMTGLVRN CPPNQALCPV
360 370 380 390 400
NLFTSCCGEF ITADPRRECY EEKADQQLHN WTMTTVSWIL IGISAFLLII
410 420
LIIMSYLAVR YKNRSVVTIK KVCLEN
Length:426
Mass (Da):48,455
Last modified:November 23, 2004 - v1
Checksum:i5CA7D6B37BF30CE5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE600983 Genomic DNA. Translation: CAP32804.3.
RefSeqiXP_002644366.1. XM_002644320.1.

Genome annotation databases

EnsemblMetazoaiCBG14199; CBG14199; CBG14199.
GeneIDi8586361.
KEGGicbr:CBG14199.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE600983 Genomic DNA. Translation: CAP32804.3 .
RefSeqi XP_002644366.1. XM_002644320.1.

3D structure databases

ProteinModelPortali Q619N4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6238.CBG14199.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai CBG14199 ; CBG14199 ; CBG14199 .
GeneIDi 8586361.
KEGGi cbr:CBG14199.

Organism-specific databases

CTDi 8586361.
WormBasei CBG14199 ; CBP03468 ; WBGene00034774 .

Phylogenomic databases

eggNOGi NOG306642.
HOGENOMi HOG000115658.
InParanoidi Q619N4.
OMAi VERCLMT.
OrthoDBi EOG7NSB64.

Family and domain databases

Gene3Di 3.40.50.1240. 1 hit.
InterProi IPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view ]
Pfami PF00328. His_Phos_2. 1 hit.
[Graphical view ]
SUPFAMi SSF53254. SSF53254. 1 hit.
PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16.

Entry informationi

Entry nameiACP1_CAEBR
AccessioniPrimary (citable) accession number: Q619N4
Secondary accession number(s): A8XJH9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3