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Protein
Submitted name:

Interferon-induced Mx2

Gene

Mx2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: MGI
  • GTP binding Source: MGI

GO - Biological processi

  • innate immune response Source: MGI
  • metabolic process Source: GOC
  • response to virus Source: MGI
Complete GO annotation...

Keywords - Ligandi

GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon-induced Mx2Imported
Gene namesi
Name:Mx2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97244. Mx2.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ61924.

Structurei

3D structure databases

ProteinModelPortaliQ61924.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.UniRule annotation
Contains GED domain.SAAS annotation
Contains dynamin-type G (guanine nucleotide-binding) domain.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000063238.
HOVERGENiHBG008788.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR000375. Dynamin_central.
IPR001401. Dynamin_GTPase.
IPR019762. Dynamin_GTPase_CS.
IPR022812. Dynamin_SF.
IPR030381. G_DYNAMIN_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11566. PTHR11566. 1 hit.
PfamiPF01031. Dynamin_M. 1 hit.
[Graphical view]
PRINTSiPR00195. DYNAMIN.
SMARTiSM00053. DYNc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00410. G_DYNAMIN_1. 1 hit.
PS51718. G_DYNAMIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q61924-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLSTEENTG VDSVNLPSGE TGLGEKDQES VNNLCSQYEE KVRPCIDLID
60 70 80 90 100
SLPALGVEQD LALPAIAVIG DQSSGKSSVL EALSGVALPR GSGIVTRCPL
110 120 130 140 150
VLKLRKLNEG EEWRGKVSYD DIEVELSDPS EVEEAINKGQ NFIAGVGLGI
160 170 180 190 200
SDKLISLDVS SPNVPDLTLI DLPGITRVAV GNQPADIGRQ IKRLIKTYIQ
210 220 230 240 250
KQETINLVVV PSNVDIATTE ALSMAQEVDP EGDRTIGILT KPDLVDRGTE
260 270 280 290 300
DKVVDVVRNL VYHLKKGYMI VKCRGQQDIQ EQLSLTEALQ NEQIFFKEHP
310 320 330 340 350
HFRVLLEDGK ATVPCLAERL TAELISHICK SLPLLENQIK ESHQSASEEL
360 370 380 390 400
QKYGMDIPED DSEKTFFLIE KINAFNQDIT ALVQGEENVA EGECRLFTRL
410 420
RKEFLSWSKE IEKNFAKRLC CFI
Length:423
Mass (Da):46,768
Last modified:November 1, 1996 - v1
Checksum:i70F72C82C8FFA5D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03368 mRNA. Translation: AAA39778.1.
PIRiA30819.
UniGeneiMm.14157.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03368 mRNA. Translation: AAA39778.1.
PIRiA30819.
UniGeneiMm.14157.

3D structure databases

ProteinModelPortaliQ61924.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:97244. Mx2.

Phylogenomic databases

HOGENOMiHOG000063238.
HOVERGENiHBG008788.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

GenevestigatoriQ61924.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR000375. Dynamin_central.
IPR001401. Dynamin_GTPase.
IPR019762. Dynamin_GTPase_CS.
IPR022812. Dynamin_SF.
IPR030381. G_DYNAMIN_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11566. PTHR11566. 1 hit.
PfamiPF01031. Dynamin_M. 1 hit.
[Graphical view]
PRINTSiPR00195. DYNAMIN.
SMARTiSM00053. DYNc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00410. G_DYNAMIN_1. 1 hit.
PS51718. G_DYNAMIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of a second interferon-regulated murine Mx gene."
    Staeheli P., Sutcliffe J.G.
    Mol. Cell. Biol. 8:4524-4528(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ61924_MOUSE
AccessioniPrimary (citable) accession number: Q61924
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 29, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.