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Q61924

- Q61924_MOUSE

UniProt

Q61924 - Q61924_MOUSE

Protein
Submitted name:

Interferon-induced Mx2

Gene

Mx2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. GTPase activity Source: MGI
    2. GTP binding Source: MGI

    GO - Biological processi

    1. GTP catabolic process Source: GOC
    2. innate immune response Source: MGI
    3. response to virus Source: MGI

    Keywords - Ligandi

    GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Interferon-induced Mx2Imported
    Gene namesi
    Name:Mx2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:97244. Mx2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ61924.

    Structurei

    3D structure databases

    ProteinModelPortaliQ61924.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the dynamin family.UniRule annotation
    Contains GED domain.SAAS annotation
    Contains dynamin-type G (guanine nucleotide-binding) domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000063238.
    HOVERGENiHBG008788.
    InParanoidiQ61924.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR000375. Dynamin_central.
    IPR001401. Dynamin_GTPase.
    IPR019762. Dynamin_GTPase_CS.
    IPR022812. Dynamin_SF.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR11566. PTHR11566. 1 hit.
    PfamiPF01031. Dynamin_M. 1 hit.
    PF00350. Dynamin_N. 1 hit.
    [Graphical view]
    PRINTSiPR00195. DYNAMIN.
    SMARTiSM00053. DYNc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00410. DYNAMIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q61924-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVLSTEENTG VDSVNLPSGE TGLGEKDQES VNNLCSQYEE KVRPCIDLID    50
    SLPALGVEQD LALPAIAVIG DQSSGKSSVL EALSGVALPR GSGIVTRCPL 100
    VLKLRKLNEG EEWRGKVSYD DIEVELSDPS EVEEAINKGQ NFIAGVGLGI 150
    SDKLISLDVS SPNVPDLTLI DLPGITRVAV GNQPADIGRQ IKRLIKTYIQ 200
    KQETINLVVV PSNVDIATTE ALSMAQEVDP EGDRTIGILT KPDLVDRGTE 250
    DKVVDVVRNL VYHLKKGYMI VKCRGQQDIQ EQLSLTEALQ NEQIFFKEHP 300
    HFRVLLEDGK ATVPCLAERL TAELISHICK SLPLLENQIK ESHQSASEEL 350
    QKYGMDIPED DSEKTFFLIE KINAFNQDIT ALVQGEENVA EGECRLFTRL 400
    RKEFLSWSKE IEKNFAKRLC CFI 423
    Length:423
    Mass (Da):46,768
    Last modified:November 1, 1996 - v1
    Checksum:i70F72C82C8FFA5D1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    J03368 mRNA. Translation: AAA39778.1.
    PIRiA30819.
    UniGeneiMm.14157.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    J03368 mRNA. Translation: AAA39778.1 .
    PIRi A30819.
    UniGenei Mm.14157.

    3D structure databases

    ProteinModelPortali Q61924.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:97244. Mx2.

    Phylogenomic databases

    HOGENOMi HOG000063238.
    HOVERGENi HBG008788.
    InParanoidi Q61924.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q61924.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR000375. Dynamin_central.
    IPR001401. Dynamin_GTPase.
    IPR019762. Dynamin_GTPase_CS.
    IPR022812. Dynamin_SF.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR11566. PTHR11566. 1 hit.
    Pfami PF01031. Dynamin_M. 1 hit.
    PF00350. Dynamin_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00195. DYNAMIN.
    SMARTi SM00053. DYNc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00410. DYNAMIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of a second interferon-regulated murine Mx gene."
      Staeheli P., Sutcliffe J.G.
      Mol. Cell. Biol. 8:4524-4528(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ61924_MOUSE
    AccessioniPrimary (citable) accession number: Q61924
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)