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Q61895

- Q61895_MOUSE

UniProt

Q61895 - Q61895_MOUSE

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Protein
Submitted name:

mRNA

Gene
H2-K1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Involved in the presentation of foreign antigens to the immune system By similarity.SAAS annotations

GO - Molecular functioni

  1. peptide antigen binding Source: MGI
  2. receptor binding Source: RefGenome

GO - Biological processi

  1. antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent Source: MGI
  2. antigen processing and presentation of exogenous peptide antigen via MHC class I Source: MGI
  3. defense response to bacterium Source: MGI
  4. immune response Source: InterPro
  5. inner ear development Source: MGI
  6. positive regulation of T cell mediated cytotoxicity Source: MGI
Complete GO annotation...

Keywords - Biological processi

Immunity

Names & Taxonomyi

Protein namesi
Submitted name:
mRNAImported
Gene namesi
Name:H2-K1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:95904. H2-K1.

Subcellular locationi

GO - Cellular componenti

  1. external side of plasma membrane Source: MGI
  2. integral component of membrane Source: UniProtKB-KW
  3. MHC class I protein complex Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MHC ISAAS annotations

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020 PredictedImportedAdd
BLAST
Chaini21 – 368348 PredictedImportedPRO_5000143470Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotations

Proteomic databases

PRIDEiQ61895.

Expressioni

Gene expression databases

GenevestigatoriQ61895.

Structurei

3D structure databases

ProteinModelPortaliQ61895.
SMRiQ61895. Positions 22-296.

Family & Domainsi

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation
Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotations

Keywords - Domaini

SignalImported, Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG016709.
InParanoidiQ61895.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
IPR010579. MHC_I_a_C.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PF06623. MHC_I_C. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q61895-1 [UniParc]FASTAAdd to Basket

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MAPCMLLLLL AAALAPTQTR AGPHSLRYFE TAVSRPGLGK PRYMEVGYVD    50
DTEFVRFDSD AENPRYEPRA PWMEQVEPEY WEEQTQIAKG NEQRSRVNLR 100
TALRYYNQSA GGSHTIQRMS GCDVGSDWRL LRGYEQVAYD GRDYIALNED 150
LKTWTAADMA ALITKHKWEQ AGAAERRRAY LEGTCVEWLR RYLELGNATL 200
LRTDSPKAHV THHSRPEDKA TLRCWALGFY PADITLTWQL NGEELTQDME 250
LVETRPAGDG TFQKWASVVV PLGKEQYYTC HVYHQGLPEP LTLRWEPPPS 300
TVSNTVIIAV LVVLGAAIVT GAVVAFVMRR RRNTGGKGGD YALAPGSQTS 350
DLSLPDCKVM VHNPHSLA 368
Length:368
Mass (Da):41,326
Last modified:November 1, 1996 - v1
Checksum:i8DE9BACB428CD8A2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M69071 mRNA. Translation: AAA39742.1.
UniGeneiMm.422886.
Mm.439675.
Mm.440940.
Mm.466882.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M69071 mRNA. Translation: AAA39742.1 .
UniGenei Mm.422886.
Mm.439675.
Mm.440940.
Mm.466882.

3D structure databases

ProteinModelPortali Q61895.
SMRi Q61895. Positions 22-296.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q61895.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:95904. H2-K1.

Phylogenomic databases

HOVERGENi HBG016709.
InParanoidi Q61895.

Miscellaneous databases

ChiTaRSi H2-K1. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q61895.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
IPR010579. MHC_I_a_C.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PF06623. MHC_I_C. 1 hit.
[Graphical view ]
PRINTSi PR01638. MHCCLASSI.
SMARTi SM00407. IGc1. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structural diversity of the classical H-2 genes: K, D, and L."
    Pullen J.K., Horton R.M., Cai Z., Pease L.R.
    J. Immunol. 148:953-967(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: B10.RIIIImported.
    Tissue: SpleenImported.

Entry informationi

Entry nameiQ61895_MOUSE
AccessioniPrimary (citable) accession number: Q61895
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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