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Protein
Submitted name:

mRNA

Gene

H2-D1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the presentation of foreign antigens to the immune system.SAAS annotation

GO - Biological processi

Keywordsi

Biological processImmunity

Names & Taxonomyi

Protein namesi
Submitted name:
mRNAImported
Gene namesi
Name:H2-D1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:95896. H2-D1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei307 – 330HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, MHC ISAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500426634925 – 362Sequence analysisAdd BLAST338

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiQ61891.
PRIDEiQ61891.

Structurei

3D structure databases

ProteinModelPortaliQ61891.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini209 – 295Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST87

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG016709.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
IPR010579. MHC_I_a_C.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PF06623. MHC_I_C. 1 hit.
PRINTSiPR01638. MHCCLASSI.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q61891-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAMAPRTLL LLLAAALAPT QTRAGPHSMR YFTTAVSRPG HGKPRFISVG
60 70 80 90 100
YVDNTEFVRF DSDAENPRYE PRARWMEQVE PEYWERNTRI AKDNEQSFRV
110 120 130 140 150
NLRTLLGYYN QSAGGSHTLQ RLSGCDVGSD GRFLRGYRQS AYDGRDYLAL
160 170 180 190 200
NEDLKTWTAA DMAAEITRRK WEQGGEAERL RAYLEGTCVE WLRRHLKNGN
210 220 230 240 250
ATLLRTDSPK AHVTYHPRSK GEVTLRCWAL GFYPADISLT WQLNGEELTQ
260 270 280 290 300
DMELVETRPA GDGTFQKWAA VVVPLGKEQN YTCHVHHEGL PKPLTLRWEP
310 320 330 340 350
PPSTDSYMVI VAVLGVLGAM AIIGAVVAFV MMMRRNTGGK GGDYALAPGS
360
QSSEMSLRDC KA
Length:362
Mass (Da):40,563
Last modified:November 1, 1996 - v1
Checksum:iCD8DD4F1D9EB5D34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M69068 mRNA. Translation: AAA73061.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ61891_MOUSE
AccessioniPrimary (citable) accession number: Q61891
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 10, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)