ID   GPAN1_MOUSE             Reviewed;         372 AA.
AC   Q61858; Q0VBG8; Q9R065;
DT   25-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2002, sequence version 2.
DT   27-MAR-2024, entry version 156.
DE   RecName: Full=G patch domain and ankyrin repeat-containing protein 1;
DE   AltName: Full=G5 protein;
DE   AltName: Full=HLA-B-associated transcript 4;
GN   Name=Gpank1; Synonyms=Bat-4, Bat4, G5;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=C57BL/6N;
RX   PubMed=9196000; DOI=10.1007/s003359900489;
RA   Lanning D., Lafuse W.P.;
RT   "Localization of the casein kinase II beta-subunit gene within the mouse H-
RT   2 complex class III region and comparison of expression with Bat genes.";
RL   Mamm. Genome 8:519-521(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=129;
RX   PubMed=14656967; DOI=10.1101/gr.1736803;
RA   Xie T., Rowen L., Aguado B., Ahearn M.E., Madan A., Qin S., Campbell R.D.,
RA   Hood L.;
RT   "Analysis of the gene-dense major histocompatibility complex class III
RT   region and its comparison to mouse.";
RL   Genome Res. 13:2621-2636(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; L76155; AAA88316.1; -; mRNA.
DR   EMBL; AF109719; AAC82476.1; -; Genomic_DNA.
DR   EMBL; BC120637; AAI20638.1; -; mRNA.
DR   EMBL; BC120639; AAI20640.1; -; mRNA.
DR   CCDS; CCDS28685.1; -.
DR   RefSeq; NP_001122069.1; NM_001128597.1.
DR   RefSeq; NP_115849.2; NM_032460.2.
DR   AlphaFoldDB; Q61858; -.
DR   SMR; Q61858; -.
DR   IntAct; Q61858; 1.
DR   MINT; Q61858; -.
DR   STRING; 10090.ENSMUSP00000056646; -.
DR   PhosphoSitePlus; Q61858; -.
DR   PaxDb; 10090-ENSMUSP00000056646; -.
DR   ProteomicsDB; 271427; -.
DR   Antibodypedia; 27457; 70 antibodies from 21 providers.
DR   DNASU; 81845; -.
DR   Ensembl; ENSMUST00000052167.9; ENSMUSP00000056646.9; ENSMUSG00000092417.4.
DR   GeneID; 81845; -.
DR   KEGG; mmu:81845; -.
DR   UCSC; uc008cfw.1; mouse.
DR   AGR; MGI:2148975; -.
DR   CTD; 7918; -.
DR   MGI; MGI:2148975; Gpank1.
DR   VEuPathDB; HostDB:ENSMUSG00000092417; -.
DR   eggNOG; KOG2384; Eukaryota.
DR   GeneTree; ENSGT00390000003292; -.
DR   InParanoid; Q61858; -.
DR   OMA; SPQYCET; -.
DR   OrthoDB; 5317726at2759; -.
DR   PhylomeDB; Q61858; -.
DR   TreeFam; TF315384; -.
DR   BioGRID-ORCS; 81845; 4 hits in 76 CRISPR screens.
DR   ChiTaRS; Gpank1; mouse.
DR   PRO; PR:Q61858; -.
DR   Proteomes; UP000000589; Chromosome 17.
DR   RNAct; Q61858; Protein.
DR   Bgee; ENSMUSG00000092417; Expressed in epithelium of small intestine and 109 other cell types or tissues.
DR   ExpressionAtlas; Q61858; baseline and differential.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR039146; GPANK1.
DR   PANTHER; PTHR20923; BAT4 PROTEIN-RELATED; 1.
DR   PANTHER; PTHR20923:SF1; G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
DR   Genevisible; Q61858; MM.
PE   2: Evidence at transcript level;
KW   ANK repeat; Isopeptide bond; Reference proteome; Repeat; Ubl conjugation.
FT   CHAIN           1..372
FT                   /note="G patch domain and ankyrin repeat-containing protein
FT                   1"
FT                   /id="PRO_0000066973"
FT   REPEAT          124..155
FT                   /note="ANK 1"
FT   REPEAT          156..186
FT                   /note="ANK 2"
FT   DOMAIN          271..317
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   REGION          74..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          211..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          251..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          330..357
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        251..270
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CROSSLNK        306
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:O95872"
FT   CONFLICT        182
FT                   /note="A -> T (in Ref. 1; AAA88316)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   372 AA;  41011 MW;  614DD02B0A3A2BAC CRC64;
     MVGSLACHIL ALPSLHFLVS LTGMSRPSFI EFTPAADSSD LWKDGQQQPQ QEKAEPVLDG
     AAARAFYEAL IADDSSSSKP QRAEPMRERK KKRRRVTREP AAAGVPRQGR ALEDEDRMAQ
     WILLAAQNGD LTELRRLLEP QEAGGAGGNI NARDAFWWTP LMCAARAGQG AAVRYLLGRG
     AAWVGVCDLG GRDAAQLAEE AGFPEVARMV RESHGETRSP ENQNRSTPSS SQFCEDCGAH
     FEDSNHHTST AHLLSLSRRP QPSNLPLGVP TSSPGFRLLL RGGWEPGMGL GPRGEGRANP
     IPTILKRDQE GLGYRSPPQP RVTHFAARDT RAVSGRERVP RVATLSQREN RRQEEKGRAW
     ERDLRLYMNL EF
//