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Protein

G patch domain and ankyrin repeat-containing protein 1

Gene

Gpank1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
G patch domain and ankyrin repeat-containing protein 1
Alternative name(s):
G5 protein
HLA-B-associated transcript 4
Gene namesi
Name:Gpank1
Synonyms:Bat-4, Bat4, G5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:2148975. Gpank1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 372372G patch domain and ankyrin repeat-containing protein 1PRO_0000066973Add
BLAST

Proteomic databases

PaxDbiQ61858.
PRIDEiQ61858.

PTM databases

PhosphoSiteiQ61858.

Expressioni

Gene expression databases

BgeeiQ61858.
CleanExiMM_BAT4.
ExpressionAtlasiQ61858. baseline and differential.
GenevisibleiQ61858. MM.

Interactioni

Protein-protein interaction databases

IntActiQ61858. 1 interaction.
MINTiMINT-1213044.
STRINGi10090.ENSMUSP00000056646.

Structurei

3D structure databases

ProteinModelPortaliQ61858.
SMRiQ61858. Positions 124-213.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati124 – 15532ANK 1Add
BLAST
Repeati156 – 18631ANK 2Add
BLAST
Domaini271 – 31747G-patchPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 ANK repeats.Curated
Contains 1 G-patch domain.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiNOG278677.
GeneTreeiENSGT00390000003292.
HOVERGENiHBG031112.
InParanoidiQ61858.
OMAiGVCELGG.
PhylomeDBiQ61858.
TreeFamiTF315384.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR000467. G_patch_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF01585. G-patch. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 1 hit.
SM00443. G_patch. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50174. G_PATCH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q61858-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGSLACHIL ALPSLHFLVS LTGMSRPSFI EFTPAADSSD LWKDGQQQPQ
60 70 80 90 100
QEKAEPVLDG AAARAFYEAL IADDSSSSKP QRAEPMRERK KKRRRVTREP
110 120 130 140 150
AAAGVPRQGR ALEDEDRMAQ WILLAAQNGD LTELRRLLEP QEAGGAGGNI
160 170 180 190 200
NARDAFWWTP LMCAARAGQG AAVRYLLGRG AAWVGVCDLG GRDAAQLAEE
210 220 230 240 250
AGFPEVARMV RESHGETRSP ENQNRSTPSS SQFCEDCGAH FEDSNHHTST
260 270 280 290 300
AHLLSLSRRP QPSNLPLGVP TSSPGFRLLL RGGWEPGMGL GPRGEGRANP
310 320 330 340 350
IPTILKRDQE GLGYRSPPQP RVTHFAARDT RAVSGRERVP RVATLSQREN
360 370
RRQEEKGRAW ERDLRLYMNL EF
Length:372
Mass (Da):41,011
Last modified:October 25, 2002 - v2
Checksum:i614DD02B0A3A2BAC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti182 – 1821A → T in AAA88316 (PubMed:9196000).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L76155 mRNA. Translation: AAA88316.1.
AF109719 Genomic DNA. Translation: AAC82476.1.
BC120637 mRNA. Translation: AAI20638.1.
BC120639 mRNA. Translation: AAI20640.1.
CCDSiCCDS28685.1.
RefSeqiNP_001122069.1. NM_001128597.1.
NP_115849.2. NM_032460.2.
UniGeneiMm.7405.

Genome annotation databases

EnsembliENSMUST00000052167; ENSMUSP00000056646; ENSMUSG00000092417.
GeneIDi81845.
KEGGimmu:81845.
UCSCiuc008cfw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L76155 mRNA. Translation: AAA88316.1.
AF109719 Genomic DNA. Translation: AAC82476.1.
BC120637 mRNA. Translation: AAI20638.1.
BC120639 mRNA. Translation: AAI20640.1.
CCDSiCCDS28685.1.
RefSeqiNP_001122069.1. NM_001128597.1.
NP_115849.2. NM_032460.2.
UniGeneiMm.7405.

3D structure databases

ProteinModelPortaliQ61858.
SMRiQ61858. Positions 124-213.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ61858. 1 interaction.
MINTiMINT-1213044.
STRINGi10090.ENSMUSP00000056646.

PTM databases

PhosphoSiteiQ61858.

Proteomic databases

PaxDbiQ61858.
PRIDEiQ61858.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000052167; ENSMUSP00000056646; ENSMUSG00000092417.
GeneIDi81845.
KEGGimmu:81845.
UCSCiuc008cfw.1. mouse.

Organism-specific databases

CTDi7918.
MGIiMGI:2148975. Gpank1.

Phylogenomic databases

eggNOGiNOG278677.
GeneTreeiENSGT00390000003292.
HOVERGENiHBG031112.
InParanoidiQ61858.
OMAiGVCELGG.
PhylomeDBiQ61858.
TreeFamiTF315384.

Miscellaneous databases

NextBioi350445.
PROiQ61858.
SOURCEiSearch...

Gene expression databases

BgeeiQ61858.
CleanExiMM_BAT4.
ExpressionAtlasiQ61858. baseline and differential.
GenevisibleiQ61858. MM.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR000467. G_patch_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF01585. G-patch. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 1 hit.
SM00443. G_patch. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50174. G_PATCH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Localization of the casein kinase II beta-subunit gene within the mouse H-2 complex class III region and comparison of expression with Bat genes."
    Lanning D., Lafuse W.P.
    Mamm. Genome 8:519-521(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: C57BL/6N.
  2. "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse."
    Xie T., Rowen L., Aguado B., Ahearn M.E., Madan A., Qin S., Campbell R.D., Hood L.
    Genome Res. 13:2621-2636(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 129.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiGPAN1_MOUSE
AccessioniPrimary (citable) accession number: Q61858
Secondary accession number(s): Q0VBG8, Q9R065
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: October 25, 2002
Last modified: June 24, 2015
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.