##gff-version 3
Q61532	UniProtKB	Chain	1	720	.	.	.	ID=PRO_0000186258;Note=Mitogen-activated protein kinase 6	
Q61532	UniProtKB	Domain	20	316	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q61532	UniProtKB	Region	638	657	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q61532	UniProtKB	Region	700	720	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q61532	UniProtKB	Motif	189	191	.	.	.	Note=SEG motif	
Q61532	UniProtKB	Motif	332	337	.	.	.	Note=FRIEDE motif	
Q61532	UniProtKB	Active site	152	152	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10027	
Q61532	UniProtKB	Binding site	26	34	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q61532	UniProtKB	Binding site	49	49	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q61532	UniProtKB	Modified residue	189	189	.	.	.	Note=Phosphoserine%3B by PAK1%2C PAK2 and PAK3;Ontology_term=ECO:0000305;evidence=ECO:0000305|PubMed:18720373;Dbxref=PMID:18720373	
Q61532	UniProtKB	Modified residue	386	386	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q16659	
Q61532	UniProtKB	Modified residue	554	554	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q16659	
Q61532	UniProtKB	Modified residue	556	556	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q16659	
Q61532	UniProtKB	Modified residue	683	683	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q16659	
Q61532	UniProtKB	Cross-link	1	1	.	.	.	Note=Peptide (Met-Gly) (interchain with G-Cter in ubiquitin);Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q61532	UniProtKB	Mutagenesis	171	171	.	.	.	Note=Kinase defective mutant%2C abolishes activity. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15577943;Dbxref=PMID:15577943	
Q61532	UniProtKB	Mutagenesis	189	189	.	.	.	Note=Unable to activate MAPKAPK5 promote MAPKAPK5 localization to the cytoplasm. S->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:15577943,ECO:0000269|PubMed:18720373;Dbxref=PMID:15577943,PMID:18720373	
Q61532	UniProtKB	Mutagenesis	189	189	.	.	.	Note=Mimicks phosphorylation state and induces constitutive protein kinase activity. S->E;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:15577943,ECO:0000269|PubMed:18720373;Dbxref=PMID:15577943,PMID:18720373	
Q61532	UniProtKB	Mutagenesis	334	334	.	.	.	Note=Abolishes binding to MAPKAPK5. I->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19473979;Dbxref=PMID:19473979	
Q61532	UniProtKB	Sequence conflict	19	19	.	.	.	Note=R->T;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q61532	UniProtKB	Sequence conflict	40	41	.	.	.	Note=ND->KY;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q61532	UniProtKB	Sequence conflict	63	63	.	.	.	Note=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q61532	UniProtKB	Sequence conflict	123	123	.	.	.	Note=P->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q61532	UniProtKB	Sequence conflict	574	574	.	.	.	Note=E->K;Ontology_term=ECO:0000305;evidence=ECO:0000305