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Protein

DNA polymerase zeta catalytic subunit

Gene

Rev3l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis.By similarity

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi3034 – 30341ZincBy similarity
Metal bindingi3037 – 30371ZincBy similarity
Metal bindingi3046 – 30461ZincBy similarity
Metal bindingi3049 – 30491ZincBy similarity
Metal bindingi3078 – 30781Iron-sulfur (4Fe-4S)By similarity
Metal bindingi3081 – 30811Iron-sulfur (4Fe-4S)By similarity
Metal bindingi3091 – 30911Iron-sulfur (4Fe-4S)By similarity
Metal bindingi3096 – 30961Iron-sulfur (4Fe-4S)By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3034 – 304916CysA-typeAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • DNA repair Source: MGI
  • DNA replication Source: UniProtKB-KW
  • error-prone translesion synthesis Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase

Keywords - Biological processi

DNA damage, DNA repair, DNA replication

Keywords - Ligandi

4Fe-4S, DNA-binding, Iron, Iron-sulfur, Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-110312. Translesion synthesis by REV1.
R-MMU-5655862. Translesion synthesis by POLK.
R-MMU-5656121. Translesion synthesis by POLI.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase zeta catalytic subunit (EC:2.7.7.7)
Alternative name(s):
Protein reversionless 3-like
Short name:
REV3-like
Seizure-related protein 4
Gene namesi
Name:Rev3l
Synonyms:Polz, Sez4
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1337131. Rev3l.

Subcellular locationi

GO - Cellular componenti

  • nucleolus Source: MGI
  • zeta DNA polymerase complex Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 31223122DNA polymerase zeta catalytic subunitPRO_0000046469Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1029 – 10291PhosphoserineCombined sources
Modified residuei1040 – 10401PhosphothreonineCombined sources
Modified residuei1964 – 19641PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ61493.
MaxQBiQ61493.
PaxDbiQ61493.
PeptideAtlasiQ61493.
PRIDEiQ61493.

PTM databases

iPTMnetiQ61493.
PhosphoSiteiQ61493.

Expressioni

Gene expression databases

BgeeiQ61493.
ExpressionAtlasiQ61493. baseline and differential.
GenevisibleiQ61493. MM.

Interactioni

Subunit structurei

Interacts with MAD2L2.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000019986.

Structurei

Secondary structure

1
3122
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi1870 – 18734Combined sources
Beta strandi1874 – 18796Combined sources
Helixi1884 – 18907Combined sources
Helixi1891 – 18933Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4FJOX-ray2.72D1865-1894[»]
ProteinModelPortaliQ61493.
SMRiQ61493. Positions 1865-1894.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1844 – 189552Mediates interaction with MAD2L2By similarityAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi3078 – 309619CysB motifAdd
BLAST

Domaini

The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.By similarity

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.Curated
Contains 1 CysA-type zinc finger.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3034 – 304916CysA-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG0968. Eukaryota.
COG0417. LUCA.
GeneTreeiENSGT00550000074640.
HOGENOMiHOG000112263.
HOVERGENiHBG000426.
InParanoidiQ61493.
KOiK02350.
OMAiFCSNPSD.
OrthoDBiEOG7F5113.
TreeFamiTF101072.

Family and domain databases

Gene3Di3.30.420.10. 2 hits.
3.90.1600.10. 2 hits.
InterProiIPR006172. DNA-dir_DNA_pol_B.
IPR017964. DNA-dir_DNA_pol_B_CS.
IPR006133. DNA-dir_DNA_pol_B_exonuc.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR023211. DNA_pol_palm_dom.
IPR032757. DUF4683.
IPR030559. PolZ_Rev3.
IPR012337. RNaseH-like_dom.
IPR025687. Znf-C4pol.
[Graphical view]
PANTHERiPTHR10322:SF5. PTHR10322:SF5. 4 hits.
PfamiPF00136. DNA_pol_B. 1 hit.
PF03104. DNA_pol_B_exo1. 2 hits.
PF15735. DUF4683. 1 hit.
PF14260. zf-C4pol. 1 hit.
[Graphical view]
PRINTSiPR00106. DNAPOLB.
SMARTiSM00486. POLBc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 4 hits.
PROSITEiPS00116. DNA_POLYMERASE_B. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q61493-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSVRIVTAD YYMASPLPGL DTCQSPLTQL PVKKVPVVRV FGATPAGQKT
60 70 80 90 100
CLHLHGIFPY LYVPYDGYGQ QPESYLSQMA FSIDRALNVA LGNPSSTAQH
110 120 130 140 150
VFKVSLVSGM PFYGYHEKER HFMKIYLYNP AMVKRICELL QSGAIMNKCY
160 170 180 190 200
QPHEAHIPYL LQLFIDYNLY GMNLINLAAV KFRKARRKGN ASHATGLFKH
210 220 230 240 250
QLSGNSPAGT LFRWEEDEIP SSLLLEGVEP LSTCELEVDA VAADILNRLD
260 270 280 290 300
IEAQIGGNPG LQAIWEDEKQ RRRNRNESSQ ISQPESQDCR FVPATESEKQ
310 320 330 340 350
FQKRLQEVLK QNDFSVTLSG SVDYSNGSQE FSAELTLHSE ILSPEMLPCS
360 370 380 390 400
PANMIEVHKD TDLSKGNTKH KVEEALINEE AILNLIENSQ TFQPLTQRLS
410 420 430 440 450
ETPVFMGSSP DESLVHLLAG LESDGYQGEK NRMPLPCHSF GESQNPQNSD
460 470 480 490 500
DEENEPQIEK EEMELSVVMS QRWDSDIEEH CAKKRSLCRN AHRSSTEEDD
510 520 530 540 550
SSSEEEMEWT DNSLLFANLS IPQLDGTADE NSDNPLNNEN SRAHSSVIAT
560 570 580 590 600
SKLSVRPSIF HKDAATLEPP SSAKITFQCK HTSALSSHVL NKDGLTEDLS
610 620 630 640 650
QPNSTEKGRD NSVTFTKEST YSMKYSGSLS STVHSDNSHK EICKKDKSLP
660 670 680 690 700
VSSCESSVFD YEEDIPSVTR QVPSRKYSNM RKIEKDASCI HVNRHISETI
710 720 730 740 750
LGKNSFNFAD LNHSKRKLSS EGNEKGNSTS LSGVFPSSLT ENCDLLPSSG
760 770 780 790 800
ENRSMAHSLE SITDESGLNK LKIRYEEFQE HKMEKPSLSQ QAAHYMFFPS
810 820 830 840 850
VVLSNCLTRP QKLSPVTYKL QSGNKPSRLK LNKKKLIGLQ ETSTKSTETG
860 870 880 890 900
ATKDSCTHND LYTGASEKEN GLSSDSAKAT HGTFENKPPT EHFIDCHFGD
910 920 930 940 950
GSLEAEQSFG LYGNKYTLRA KRKVNYETED SESSFVTQNS KISLPHPMEI
960 970 980 990 1000
GENLDGTLKS RKRRKMSKKL PPVIIKYIII NRFRGRKNML VKLGKIDSKE
1010 1020 1030 1040 1050
KQVILTEEKM ELYKKLAPLK DFWPKVPDSP ATKYPIYPLT PKKSHRRKSK
1060 1070 1080 1090 1100
HKSAKKKPGK QHRTNSENIK RTLSFRKKRT HAVLSPPSPS YIAETEDCDL
1110 1120 1130 1140 1150
SYSDVMSKLG FLSERSTSPI NSSPPRCWSP TDPRAEEIMA AAEKESMLFK
1160 1170 1180 1190 1200
GPNVYNTKTV SPRVGKASRA RAQVKKSKAR LANSSVVTNK RNKRNQTTKL
1210 1220 1230 1240 1250
VDDGKKKPRA KQKQRANEKS LSRKHAIPAD EKMKPHSEAE LTPNHQSVSE
1260 1270 1280 1290 1300
LTSSSGAQAL SKQKEMSQTG PAVDHPLPPA QPTGISAQQR LSNCFSSFLE
1310 1320 1330 1340 1350
SKKSVDLRTF PSSRDDSHSS VVYSSIGPGI SKINIQRSHN QSAMFTRKET
1360 1370 1380 1390 1400
TLIQKSIFDL SNHLSQVAQS TQVCSGIISP KTEESSSTQK NCGSSMGKLN
1410 1420 1430 1440 1450
EYRSSLESKP EQVCAPNFLH CKDSQQQTVS VSEQSKTSET CSPGNAASEE
1460 1470 1480 1490 1500
SQTPNCFVTS LKSPIKQIAW EQKQRGFILD MSNFKPEKVK QRSLSEAISQ
1510 1520 1530 1540 1550
TKALSQCKNQ NVSTPSVFGE GQSGLAVLKE LLQKRQQKAQ STNVVQDSTS
1560 1570 1580 1590 1600
THQPDKNISV SNEHKKANKR TRPVTSPRKP RTPRRTKPKE QTPRRLKVDP
1610 1620 1630 1640 1650
LNLQTSGHLD NSLSDDSPIL FSDPGFESCY SLEDSLSPEH NYNFDINTIG
1660 1670 1680 1690 1700
QTGFCSFYSG SQFVPADQNL PQKFLSDAVQ DLFPGQAIDK SELLSHDRQS
1710 1720 1730 1740 1750
CSEEKHHVSD SSPWIRASTL NPELFEKVAM DNNENHRHSQ WKNSFHPLTS
1760 1770 1780 1790 1800
HSNSIMESFC VQQAENCLTE KSRLNRSSVS KEVFLSLPQA NSSDWIQGHN
1810 1820 1830 1840 1850
RKEADQSLHS ANTSFTTILS SPDGELVDAA SEDLELYVSR NNDVLTPTPD
1860 1870 1880 1890 1900
SSPRSTSSPL QSKNGSFTPR TAHILKPLMS PPSREEIVAT LLDHDLSEAI
1910 1920 1930 1940 1950
YQEPFCSNPS DVPEKPREIG GRLLMVETRL PNDLIEFEGD FSLEGLRLWK
1960 1970 1980 1990 2000
TAFSAMTQNP RPGSPLRNGQ AVVNKESSNS HKMVEDKKIV IMPCKYAPSR
2010 2020 2030 2040 2050
QLVQAWLQAK EEYERSKKLP KTELTPVTKS AENVSPSLNP GDTCAVSPQV
2060 2070 2080 2090 2100
DKCPHTLSSS AHTKEEVSKS QIALQTSTTG CSQTLLAAAS AAVPEEDEDD
2110 2120 2130 2140 2150
NDNCYVSYSS PDSPGIPPWQ QAASPDFRSL NGDDRHSSPG KELCSLAVEN
2160 2170 2180 2190 2200
FLKPIKDGIQ KSSCSESWEP QVISPIHARA RTGKWDPLCL HSTPVMQRKF
2210 2220 2230 2240 2250
LEKLPEATGL SPLSVEPKTQ KLYNKKGSDA DGLRRVLLTT QVENQFAAVN
2260 2270 2280 2290 2300
TPKKETSQID GPSLNNTYGF KVSIQNLQEA KALHEIQNLT LISVELHART
2310 2320 2330 2340 2350
RRDLQPDPEF DPICALFYCI SSDTPLPDTE KTELTGVIVI DKDKTVTHQD
2360 2370 2380 2390 2400
IRSQTPLLIR SGITGLEVTY AADEKALFQE ITNIIKRYDP DILLGYEIQM
2410 2420 2430 2440 2450
HSWGYLLQRA AALSVDLCQM ISRVPDDKIE NRFAAERDDY GSDTMSEINI
2460 2470 2480 2490 2500
VGRITLNLWR IMRNEVALTN YTFENVSFHV LHQRFPLFTF RVLSDWFDNK
2510 2520 2530 2540 2550
TDLYRWKMVD HYVSRVRGNL QMLEQLDLIG KTSEMARLFG IQFLHVLTRG
2560 2570 2580 2590 2600
SQYRVESMML RIAKPMNYIP VTPSIQQRSQ MRAPQCVPLI MEPESRFYSN
2610 2620 2630 2640 2650
SVLVLDFQSL YPSIVIAYNY CFSTCLGHVE NLGKYDEFKF GCTSLRVPPD
2660 2670 2680 2690 2700
LLYQIRHDVT VSPNGVAFVK PSVRKGVLPR MLEEILKTRL MVKQSMKSYK
2710 2720 2730 2740 2750
QDRALSRMLN ARQLGLKLIA NVTFGYTAAN FSGRMPCIEV GDSIVHKARE
2760 2770 2780 2790 2800
TLERAIKLVN DTKKWGARVV YGDTDSMFVL LKGATKEQSF KIGQEIAEAV
2810 2820 2830 2840 2850
TATNPRPVKL KFEKVYLPCV LQTKKRYVGY MYETLDQKEP VFDAKGIETV
2860 2870 2880 2890 2900
RRDSCPAVSK ILERSLKLLF ETRDISLIKQ YVQRQCMKLV EGKASIQDFI
2910 2920 2930 2940 2950
FAKEYRGSFS YRPGACVPAL ELTRKMLAYD RRSEPRVGER VPYVIIYGTP
2960 2970 2980 2990 3000
GLPLIQLIRR PAEVLQDPTL RLNATYYITK QILPPLARIF SLIGIDVFSW
3010 3020 3030 3040 3050
YQELPRIQKA TSSSRSELEG RKGTISQYFT TLHCPVCDDL TQHGICSKCR
3060 3070 3080 3090 3100
SQPQHVAIIL NQEIRELERK QEQLIKICRN CTGSFDRHIP CVSLNCPVLF
3110 3120
KLSRVNRELS KAPYLRQLLD QF
Length:3,122
Mass (Da):350,711
Last modified:July 27, 2011 - v3
Checksum:i1D365BD1CD5548C2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti92 – 921G → A in BAA90768 (Ref. 2) Curated
Sequence conflicti294 – 2941A → T in BAA90768 (Ref. 2) Curated
Sequence conflicti578 – 5781Q → E in AAC98785 (PubMed:10102037).Curated
Sequence conflicti609 – 6091R → Q in BAA90768 (Ref. 2) Curated
Sequence conflicti1278 – 12781P → L in AAC98785 (PubMed:10102037).Curated
Sequence conflicti1298 – 12981F → L in AAC98785 (PubMed:10102037).Curated
Sequence conflicti1416 – 14161P → L in BAA90768 (Ref. 2) Curated
Sequence conflicti1848 – 18481T → A in AAC98785 (PubMed:10102037).Curated
Sequence conflicti2368 – 23681V → G in BAA11461 (PubMed:8645260).Curated
Sequence conflicti2467 – 24671A → G in AAC98785 (PubMed:10102037).Curated
Sequence conflicti2467 – 24671A → G in BAA90768 (Ref. 2) Curated
Sequence conflicti2467 – 24671A → G in BAA11461 (PubMed:8645260).Curated
Sequence conflicti2883 – 28831Q → H in AAC98785 (PubMed:10102037).Curated
Sequence conflicti2883 – 28831Q → H in BAA90768 (Ref. 2) Curated
Sequence conflicti2883 – 28831Q → H in BAA11461 (PubMed:8645260).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF083464 mRNA. Translation: AAC98785.1.
AB031049 mRNA. Translation: BAA90768.1.
AC118733 Genomic DNA. No translation available.
AC119943 Genomic DNA. No translation available.
D78644 mRNA. Translation: BAA11461.1.
CCDSiCCDS23790.1.
PIRiT17202.
RefSeqiNP_035394.2. NM_011264.3.
UniGeneiMm.439723.

Genome annotation databases

EnsembliENSMUST00000019986; ENSMUSP00000019986; ENSMUSG00000019841.
ENSMUST00000164763; ENSMUSP00000131519; ENSMUSG00000019841.
GeneIDi19714.
KEGGimmu:19714.
UCSCiuc007ewc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF083464 mRNA. Translation: AAC98785.1.
AB031049 mRNA. Translation: BAA90768.1.
AC118733 Genomic DNA. No translation available.
AC119943 Genomic DNA. No translation available.
D78644 mRNA. Translation: BAA11461.1.
CCDSiCCDS23790.1.
PIRiT17202.
RefSeqiNP_035394.2. NM_011264.3.
UniGeneiMm.439723.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4FJOX-ray2.72D1865-1894[»]
ProteinModelPortaliQ61493.
SMRiQ61493. Positions 1865-1894.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000019986.

PTM databases

iPTMnetiQ61493.
PhosphoSiteiQ61493.

Proteomic databases

EPDiQ61493.
MaxQBiQ61493.
PaxDbiQ61493.
PeptideAtlasiQ61493.
PRIDEiQ61493.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000019986; ENSMUSP00000019986; ENSMUSG00000019841.
ENSMUST00000164763; ENSMUSP00000131519; ENSMUSG00000019841.
GeneIDi19714.
KEGGimmu:19714.
UCSCiuc007ewc.1. mouse.

Organism-specific databases

CTDi5980.
MGIiMGI:1337131. Rev3l.

Phylogenomic databases

eggNOGiKOG0968. Eukaryota.
COG0417. LUCA.
GeneTreeiENSGT00550000074640.
HOGENOMiHOG000112263.
HOVERGENiHBG000426.
InParanoidiQ61493.
KOiK02350.
OMAiFCSNPSD.
OrthoDBiEOG7F5113.
TreeFamiTF101072.

Enzyme and pathway databases

ReactomeiR-MMU-110312. Translesion synthesis by REV1.
R-MMU-5655862. Translesion synthesis by POLK.
R-MMU-5656121. Translesion synthesis by POLI.

Miscellaneous databases

ChiTaRSiRev3l. mouse.
PROiQ61493.
SOURCEiSearch...

Gene expression databases

BgeeiQ61493.
ExpressionAtlasiQ61493. baseline and differential.
GenevisibleiQ61493. MM.

Family and domain databases

Gene3Di3.30.420.10. 2 hits.
3.90.1600.10. 2 hits.
InterProiIPR006172. DNA-dir_DNA_pol_B.
IPR017964. DNA-dir_DNA_pol_B_CS.
IPR006133. DNA-dir_DNA_pol_B_exonuc.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR023211. DNA_pol_palm_dom.
IPR032757. DUF4683.
IPR030559. PolZ_Rev3.
IPR012337. RNaseH-like_dom.
IPR025687. Znf-C4pol.
[Graphical view]
PANTHERiPTHR10322:SF5. PTHR10322:SF5. 4 hits.
PfamiPF00136. DNA_pol_B. 1 hit.
PF03104. DNA_pol_B_exo1. 2 hits.
PF15735. DUF4683. 1 hit.
PF14260. zf-C4pol. 1 hit.
[Graphical view]
PRINTSiPR00106. DNAPOLB.
SMARTiSM00486. POLBc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 4 hits.
PROSITEiPS00116. DNA_POLYMERASE_B. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning, expression and chromosomal localisation of the mouse Rev3l gene, encoding the catalytic subunit of polymerase zeta."
    van Sloun P.P.H., Romeijn R.J., Eeken J.C.J.
    Mutat. Res. 433:109-116(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: 129/Ola.
    Tissue: Testis.
  2. "Molecular analyses of Sez4 encoding murine homologue of yeast REV3 in brain neurons."
    Kajiwara K.
    Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. "Molecular characterization of seizure-related genes isolated by differential screening."
    Kajiwara K., Nagawawa H., Shimizu-Nishikawa K., Ookura T., Kimura M., Sugaya E.
    Biochem. Biophys. Res. Commun. 219:795-799(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2368-3122.
    Strain: C57BL/6J.
    Tissue: Embryonic brain.
  5. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1029 AND THR-1040, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Testis.

Entry informationi

Entry nameiDPOLZ_MOUSE
AccessioniPrimary (citable) accession number: Q61493
Secondary accession number(s): E9Q1X0, Q9JMD6, Q9QWX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: July 27, 2011
Last modified: July 6, 2016
This is version 137 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.