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Q61268 (APOC4_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Apolipoprotein C-IV

Short name=Apo-CIV
Short name=ApoC-IV
Alternative name(s):
Apolipoprotein C2-linked
Short name=ACL
Apolipoprotein C4
Gene names
Name:Apoc4
Synonyms:Acl
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length124 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May participate in lipoprotein metabolism.

Subcellular location

Secreted.

Tissue specificity

Expressed by the liver and secreted in plasma.

Sequence similarities

Belongs to the apolipoprotein C4 family.

Ontologies

Keywords
   Biological processLipid transport
Transport
   Cellular componentSecreted
   DomainSignal
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processlipid transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentvery-low-density lipoprotein particle

Inferred from direct assay PubMed 12700345. Source: BHF-UCL

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Potential
Chain28 – 12497Apolipoprotein C-IV
PRO_0000002037

Amino acid modifications

Glycosylation1071N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q61268 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 97C3CDEE72C9A452

FASTA12414,288
        10         20         30         40         50         60 
MSLLRCRPRD LPSVSLSVLF LVSFVASMST ESLSPTPGPE SSRWSLVRAR VLEMVEPLVT 

        70         80         90        100        110        120 
RTRDRWQWFW GPGAVQGFMQ TYYEDHLKDL GPRTQAWLQS SRDHLLNKTH SLCPRLLCKD 


RTQG 

« Hide

References

« Hide 'large scale' references
[1]"The apolipoprotein C2-linked (Acl) gene: a new gene within the mouse apolipoprotein e-c1-c2 gene cluster."
van Eck M.M., Hoffer M.J., Havekes L.M., Frants R.R., Hofker M.H.
Genomics 21:110-115(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: C57BL/6.
Tissue: Liver.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Liver.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z24722 Genomic DNA. Translation: CAA80850.1.
BC024657 mRNA. Translation: AAH24657.1.
CCDSCCDS20910.1.
PIRA54773.
RefSeqNP_031411.1. NM_007385.3.
UniGeneMm.477720.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000003071.

Proteomic databases

PaxDbQ61268.
PRIDEQ61268.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000003071; ENSMUSP00000003071; ENSMUSG00000074336.
GeneID11425.
KEGGmmu:11425.
UCSCuc009fmu.1. mouse.

Organism-specific databases

CTD346.
MGIMGI:87878. Apoc4.

Phylogenomic databases

eggNOGNOG39292.
GeneTreeENSGT00390000015914.
HOGENOMHOG000034003.
HOVERGENHBG050550.
InParanoidQ61268.
OMAKTHSLCP.
OrthoDBEOG76MKBG.
PhylomeDBQ61268.
TreeFamTF336879.

Gene expression databases

BgeeQ61268.
GenevestigatorQ61268.

Family and domain databases

InterProIPR028120. APOC4.
[Graphical view]
PANTHERPTHR32288. PTHR32288. 1 hit.
PfamPF15119. APOC4. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio278678.
PROQ61268.
SOURCESearch...

Entry information

Entry nameAPOC4_MOUSE
AccessionPrimary (citable) accession number: Q61268
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot