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Q61268

- APOC4_MOUSE

UniProt

Q61268 - APOC4_MOUSE

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Protein

Apolipoprotein C-IV

Gene

Apoc4

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

May participate in lipoprotein metabolism.

GO - Biological processi

  1. lipid transport Source: UniProtKB-KW
  2. positive regulation of sequestering of triglyceride Source: Ensembl
  3. triglyceride homeostasis Source: Ensembl
Complete GO annotation...

Keywords - Biological processi

Lipid transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Apolipoprotein C-IV
Short name:
Apo-CIV
Short name:
ApoC-IV
Alternative name(s):
Apolipoprotein C2-linked
Short name:
ACL
Apolipoprotein C4
Gene namesi
Name:Apoc4
Synonyms:Acl
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:87878. Apoc4.

Subcellular locationi

GO - Cellular componenti

  1. high-density lipoprotein particle Source: Ensembl
  2. very-low-density lipoprotein particle Source: BHF-UCL
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence AnalysisAdd
BLAST
Chaini28 – 12497Apolipoprotein C-IVPRO_0000002037Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi107 – 1071N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ61268.
PaxDbiQ61268.
PRIDEiQ61268.

Expressioni

Tissue specificityi

Expressed by the liver and secreted in plasma.

Gene expression databases

BgeeiQ61268.
GenevestigatoriQ61268.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003071.

Family & Domainsi

Sequence similaritiesi

Belongs to the apolipoprotein C4 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG39292.
GeneTreeiENSGT00390000015914.
HOGENOMiHOG000034003.
HOVERGENiHBG050550.
InParanoidiQ61268.
OMAiKTHSLCP.
OrthoDBiEOG76MKBG.
PhylomeDBiQ61268.
TreeFamiTF336879.

Family and domain databases

InterProiIPR028120. APOC4.
[Graphical view]
PANTHERiPTHR32288. PTHR32288. 1 hit.
PfamiPF15119. APOC4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q61268-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLLRCRPRD LPSVSLSVLF LVSFVASMST ESLSPTPGPE SSRWSLVRAR
60 70 80 90 100
VLEMVEPLVT RTRDRWQWFW GPGAVQGFMQ TYYEDHLKDL GPRTQAWLQS
110 120
SRDHLLNKTH SLCPRLLCKD RTQG
Length:124
Mass (Da):14,288
Last modified:November 1, 1997 - v1
Checksum:i97C3CDEE72C9A452
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z24722 Genomic DNA. Translation: CAA80850.1.
BC024657 mRNA. Translation: AAH24657.1.
CCDSiCCDS20910.1.
PIRiA54773.
RefSeqiNP_031411.1. NM_007385.3.
UniGeneiMm.477720.

Genome annotation databases

EnsembliENSMUST00000003071; ENSMUSP00000003071; ENSMUSG00000074336.
GeneIDi11425.
KEGGimmu:11425.
UCSCiuc009fmu.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z24722 Genomic DNA. Translation: CAA80850.1 .
BC024657 mRNA. Translation: AAH24657.1 .
CCDSi CCDS20910.1.
PIRi A54773.
RefSeqi NP_031411.1. NM_007385.3.
UniGenei Mm.477720.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000003071.

Proteomic databases

MaxQBi Q61268.
PaxDbi Q61268.
PRIDEi Q61268.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000003071 ; ENSMUSP00000003071 ; ENSMUSG00000074336 .
GeneIDi 11425.
KEGGi mmu:11425.
UCSCi uc009fmu.1. mouse.

Organism-specific databases

CTDi 346.
MGIi MGI:87878. Apoc4.

Phylogenomic databases

eggNOGi NOG39292.
GeneTreei ENSGT00390000015914.
HOGENOMi HOG000034003.
HOVERGENi HBG050550.
InParanoidi Q61268.
OMAi KTHSLCP.
OrthoDBi EOG76MKBG.
PhylomeDBi Q61268.
TreeFami TF336879.

Miscellaneous databases

NextBioi 278678.
PROi Q61268.
SOURCEi Search...

Gene expression databases

Bgeei Q61268.
Genevestigatori Q61268.

Family and domain databases

InterProi IPR028120. APOC4.
[Graphical view ]
PANTHERi PTHR32288. PTHR32288. 1 hit.
Pfami PF15119. APOC4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The apolipoprotein C2-linked (Acl) gene: a new gene within the mouse apolipoprotein e-c1-c2 gene cluster."
    van Eck M.M., Hoffer M.J., Havekes L.M., Frants R.R., Hofker M.H.
    Genomics 21:110-115(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: C57BL/6.
    Tissue: Liver.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Liver.

Entry informationi

Entry nameiAPOC4_MOUSE
AccessioniPrimary (citable) accession number: Q61268
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3