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Protein
Submitted name:

TAP2

Gene

Tap2

Organism
Mus musculus castaneus (Southeastern Asian house mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi503 – 510ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
TAP2Imported
Gene namesi
Name:Tap2Imported
Synonyms:TAP2-casImported
OrganismiMus musculus castaneus (Southeastern Asian house mouse)Imported
Taxonomic identifieri10091 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98484 Tap2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei52 – 79HelicalSequence analysisAdd BLAST28
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Transmembranei149 – 169HelicalSequence analysisAdd BLAST21
Transmembranei189 – 216HelicalSequence analysisAdd BLAST28
Transmembranei270 – 288HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500426668429 – 703Sequence analysisAdd BLAST675

Proteomic databases

PRIDEiQ61231

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ61231
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini153 – 435ABC transmembrane type-1InterPro annotationAdd BLAST283
Domaini468 – 702ABC transporterInterPro annotationAdd BLAST235

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG008358

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR013305 ABC_Tap-like
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
IPR005293 Tap2/ABCB3
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
PRINTSiPR01897 TAP2PROTEIN
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
TIGRFAMsiTIGR00958 3a01208, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q61231-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSYLRPWV SLLLADMALL GLLQGSLGNL LPQGLPGLWI EGTLRLGVLW
60 70 80 90 100
GLLKVGGLLG LVGTLLPLLC LATPLFFSLR ALVGGTASTS VVRVASASWG
110 120 130 140 150
WLLAGYGAVA LSWAVWAVLS PAGVQEKEPG QENRTLLMKR LLKLSRPDLP
160 170 180 190 200
FLIAAFFFLV VAVWGETLIP RYSGRVIDIL GGDFDPDAFA SAIFFMCLFS
210 220 230 240 250
VGSSFSAGCR GGSFLFTMSR INLRIREQLF SSLLRQDLGF FQETKTGELN
260 270 280 290 300
SRLSSDTSLM SRWLPFNANI LLRSLVKVVG LYFFMLQVSP RLTFLSLLDL
310 320 330 340 350
PLTIAAEKVY NPRHQAVLKE IQDAVAKAGQ VVREAVGGLQ TVRSFGAEEQ
360 370 380 390 400
EVSRYKEALE RCRQLWWRRD LEKDVYLVIR RVMALGMQVL ILNCGVQQIL
410 420 430 440 450
AGEVTRGGLL SFLLYQEEVG QYVRNLVYMY GDMLSNVGAA EKVFSYLDRR
460 470 480 490 500
PNLPQPGILA PPWLEGRVEF QDVSFSYPRR PEKPVLQGLT FTLHPGTVTA
510 520 530 540 550
LVGPNGSGKS TVAALLQNLY QPTGGQLLLD GEPLTEYDHH YLHRQVVLVG
560 570 580 590 600
QEPVLFSGSV KDNIAYGLRD CEDAQVMAAA QAACADDFIG EMTNGINTEI
610 620 630 640 650
GEKGGQLAVG QKQRLAIARA LVRNPRVLIL DEATSALDAQ CEQALQNWRS
660 670 680 690 700
QGDRTMLVIA HRLHTVQNAD QVLVLKQGRL VEHDQLRDGQ DVYAHLVQQR

LEA
Length:703
Mass (Da):77,533
Last modified:November 1, 1996 - v1
Checksum:i722DF3E456DF65F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60091 mRNA Translation: AAB41968.1
UniGeneiMm.14814

Entry informationi

Entry nameiQ61231_MUSMC
AccessioniPrimary (citable) accession number: Q61231
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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