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Protein
Submitted name:

TAP2

Gene

Tap2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
TAP2Imported
Gene namesi
Name:Tap2Imported
Synonyms:TAP2-dImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98484. Tap2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei58 – 7922HelicalSequence analysisAdd
BLAST
Transmembranei99 – 11921HelicalSequence analysisAdd
BLAST
Transmembranei149 – 16921HelicalSequence analysisAdd
BLAST
Transmembranei189 – 21628HelicalSequence analysisAdd
BLAST
Transmembranei270 – 28819HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ61227.
PeptideAtlasiQ61227.
PRIDEiQ61227.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025197.

Structurei

3D structure databases

ProteinModelPortaliQ61227.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini153 – 435283ABC transmembrane type-1InterPro annotationAdd
BLAST
Domaini468 – 702235ABC transporterInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transporter domain.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0058. Eukaryota.
COG1132. LUCA.
HOVERGENiHBG008358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR013305. ABC_Tap-like.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
IPR005293. Tap2/ABCB3.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
PRINTSiPR01897. TAP2PROTEIN.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
TIGRFAMsiTIGR00958. 3a01208. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q61227-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSYLRPWV SLLLADMALL GLLQGSLGNL LPQGLPGLWI EGTLRLGVLW
60 70 80 90 100
GLLKVGRLLG LVGTLLPLLC LATPLFFSLR ALVGGTASTS VVRVASASWG
110 120 130 140 150
WLLAGYGAAA LSWAVWAVLS PAGVQEKEPG QENRTLLMKR LLKLSRPDLP
160 170 180 190 200
FLIAAFFFLV VAVWGETLIP RYSGRVIDIL GGDFDPDAFA SAIFFMCLFS
210 220 230 240 250
VGSSFSAGCR GGSFLFTMSR INLRIREQLF SSLLRQDLGF FQETKTGELN
260 270 280 290 300
SRLSSDTSLM SRWLPFNANI LLRSLVKVVG LYFFMLQVSP RLTFLSLLDL
310 320 330 340 350
PLTIAAEKVY NPRHQAVLKE IQDAVAKAGQ VVREAVGGLQ TVRSFGAEEQ
360 370 380 390 400
EVSRYKEALE RCRQLWWRRD LEKDVYLVIR RVMALGMQVL ILNCGVQQIL
410 420 430 440 450
AGEVTRGGLL SFLLYQEEVG QYVRNLVYMY GDMLSNVGAA EKVFSYLDRR
460 470 480 490 500
PNLPQPGILA PPWLEGRVEF QDVSFSYPRR PEKPVLQGLT FTLHPGTVTA
510 520 530 540 550
LVGPNGSGKS TVAALLQNLY QPTGGQLLLD GEPLTEYDHH YLHRQVVLVG
560 570 580 590 600
QEPVLFSGSV KDNIAYGLRD CEDAQVMAAA QAACADDFIG EMTNGINTEI
610 620 630 640 650
GEKGGQLAVG QKQRLAIARA LVRNPRVLIL DEATSALDAQ CEQALQNWRS
660 670 680 690 700
QGDRTMLVIA HRLHTVQNAD QVLVLKQGRL VEHDQLRDGQ DVYAHLVQQR

LEA
Length:703
Mass (Da):77,604
Last modified:November 1, 1996 - v1
Checksum:i71736BD8039FF8B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60087 mRNA. Translation: AAB41970.1.
UniGeneiMm.14814.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60087 mRNA. Translation: AAB41970.1.
UniGeneiMm.14814.

3D structure databases

ProteinModelPortaliQ61227.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025197.

Proteomic databases

PaxDbiQ61227.
PeptideAtlasiQ61227.
PRIDEiQ61227.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:98484. Tap2.

Phylogenomic databases

eggNOGiKOG0058. Eukaryota.
COG1132. LUCA.
HOVERGENiHBG008358.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR013305. ABC_Tap-like.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
IPR005293. Tap2/ABCB3.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
PRINTSiPR01897. TAP2PROTEIN.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
TIGRFAMsiTIGR00958. 3a01208. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Allelic variation in the mouse Tap-1 and Tap-2 transporter genes."
    Marusina K., Iyer M., Monaco J.J.
    J. Immunol. 158:5251-5256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.

Entry informationi

Entry nameiQ61227_MOUSE
AccessioniPrimary (citable) accession number: Q61227
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.