Q61057 (Q61057_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Trp-related protein 2 EMBL AAC52700.1

Gene names

Name:

Trpc2 MGI 109527

Organism

Mus musculus (Mouse) EMBL AAC52700.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	105 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	Transmembrane RuleBase RU003378
Molecular function	Ion channel RuleBase RU003378
Gene Ontology (GO)
Biological_process	acrosome reaction Inferred from mutant phenotype PubMed 11331878. Source: MGI elevation of cytosolic calcium ion concentration Inferred from physical interaction PubMed 10051594. Source: MGI female courtship behavior Inferred from mutant phenotype PubMed 17676034. Source: MGI inter-male aggressive behavior Inferred from mutant phenotype PubMed 11823606. Source: MGI mating behavior, sex discrimination Inferred from mutant phenotype PubMed 11823606PubMed 11972034. Source: MGI response to pheromone Inferred from mutant phenotype PubMed 11823606PubMed 11972034. Source: MGI territorial aggressive behavior Inferred from mutant phenotype PubMed 11972034PubMed 17676034. Source: MGI
Cellular_component	Golgi membrane Inferred from direct assay PubMed 10998353. Source: MGI dendrite membrane Inferred from mutant phenotype PubMed 14642279. Source: MGI endoplasmic reticulum membrane Inferred from direct assay PubMed 10998353. Source: MGI integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW nuclear envelope Inferred from direct assay PubMed 10998353. Source: MGI
Molecular_function	calmodulin binding Inferred from direct assay PubMed 12601176. Source: MGI diacylglycerol binding Inferred from mutant phenotype PubMed 14642279. Source: MGI store-operated calcium channel activity Inferred from direct assay PubMed 10051594. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC52700.1
	Non-terminal residue	105	1	EMBL AAC52700.1

Sequences

	Sequence		Length	Mass (Da)
	Q61057 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: B6176F90E086A253	FASTA	105	12,283
	10 20 30 40 50 60 DDMIRFMFIL MIILTAFLCG LNNIYVPYQE SEKLGNFNET FQFLFWTMFG MEEHTVVDMP 70 80 90 100 QFLVPEFVGR AMYGIFTIVM VIVLLNMLIA MITNSFQKIE DDADV

References

[1]	"trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry." Zhu X., Jiang M., Peyton M., Boulay G., Hurst R., Stefani E., Birnbaumer L. Cell 85:661-671(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U40981 mRNA. Translation: AAC52700.1.
IPI	IPI00230563.
UniGene	Mm.292904.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q61057.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:109527. Trpc2.
Phylogenomic databases
InParanoid	Q61057.
Gene expression databases
ArrayExpress	Q61057.
Bgee	Q61057.
Genevestigator	Q61057.
Family and domain databases
InterPro	IPR005821. Ion_trans_dom. IPR005458. TRPC2_channel. IPR002153. TRPC_channel. [Graphical view]
PANTHER	PTHR10117. PTHR10117. 1 hit. PTHR10117:SF6. PTHR10117:SF6. 1 hit.
Pfam	PF00520. Ion_trans. 1 hit. [Graphical view]
PRINTS	PR01097. TRNSRECEPTRP.
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q61057_MOUSE

Accession

Primary (citable) accession number: Q61057

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)