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Q61057

- Q61057_MOUSE

UniProt

Q61057 - Q61057_MOUSE

Protein
Submitted name:

Trp-related protein 2

Gene

Trpc2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. calmodulin binding Source: MGI
    2. diacylglycerol binding Source: MGI
    3. protein binding Source: MGI
    4. store-operated calcium channel activity Source: MGI

    GO - Biological processi

    1. acrosome reaction Source: MGI
    2. calcium ion transport Source: MGI
    3. female courtship behavior Source: MGI
    4. inter-male aggressive behavior Source: MGI
    5. mating behavior, sex discrimination Source: MGI
    6. negative regulation of male mating behavior Source: MGI
    7. positive regulation of cytosolic calcium ion concentration Source: MGI
    8. regulation of gene expression Source: MGI
    9. response to pheromone Source: MGI
    10. territorial aggressive behavior Source: MGI

    Keywords - Molecular functioni

    Ion channelUniRule annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Trp-related protein 2Imported
    Gene namesi
    Name:Trpc2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:109527. Trpc2.

    Subcellular locationi

    GO - Cellular componenti

    1. dendrite membrane Source: MGI
    2. endomembrane system Source: MGI
    3. endoplasmic reticulum membrane Source: MGI
    4. Golgi membrane Source: MGI
    5. integral component of membrane Source: UniProtKB-KW
    6. nuclear envelope Source: MGI
    7. plasma membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    BgeeiQ61057.
    GenevestigatoriQ61057.

    Family & Domainsi

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    InParanoidiQ61057.

    Family and domain databases

    InterProiIPR005821. Ion_trans_dom.
    IPR005458. TRPC2_channel.
    IPR002153. TRPC_channel.
    [Graphical view]
    PANTHERiPTHR10117. PTHR10117. 1 hit.
    PTHR10117:SF6. PTHR10117:SF6. 1 hit.
    PfamiPF00520. Ion_trans. 1 hit.
    [Graphical view]
    PRINTSiPR01097. TRNSRECEPTRP.

    Sequencei

    Sequence statusi: Fragment.

    Q61057-1 [UniParc]FASTAAdd to Basket

    « Hide

    DDMIRFMFIL MIILTAFLCG LNNIYVPYQE SEKLGNFNET FQFLFWTMFG    50
    MEEHTVVDMP QFLVPEFVGR AMYGIFTIVM VIVLLNMLIA MITNSFQKIE 100
    DDADV 105
    Length:105
    Mass (Da):12,283
    Last modified:November 1, 1996 - v1
    Checksum:iB6176F90E086A253
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei105 – 1051Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U40981 mRNA. Translation: AAC52700.1.
    UniGeneiMm.292904.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U40981 mRNA. Translation: AAC52700.1 .
    UniGenei Mm.292904.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:109527. Trpc2.

    Phylogenomic databases

    InParanoidi Q61057.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Bgeei Q61057.
    Genevestigatori Q61057.

    Family and domain databases

    InterProi IPR005821. Ion_trans_dom.
    IPR005458. TRPC2_channel.
    IPR002153. TRPC_channel.
    [Graphical view ]
    PANTHERi PTHR10117. PTHR10117. 1 hit.
    PTHR10117:SF6. PTHR10117:SF6. 1 hit.
    Pfami PF00520. Ion_trans. 1 hit.
    [Graphical view ]
    PRINTSi PR01097. TRNSRECEPTRP.
    ProtoNeti Search...

    Publicationsi

    1. "trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry."
      Zhu X., Jiang M., Peyton M., Boulay G., Hurst R., Stefani E., Birnbaumer L.
      Cell 85:661-671(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ61057_MOUSE
    AccessioniPrimary (citable) accession number: Q61057
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)