Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q61057 (Q61057_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Trpc2 MGI 109527
OrganismMus musculus (Mouse) EMBL AAC52700.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length105 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainTransmembrane RuleBase RU003378
   Molecular functionIon channel RuleBase RU003378
Gene Ontology (GO)
   Biological_processacrosome reaction

Inferred from mutant phenotype PubMed 11331878. Source: MGI

calcium ion transport

Inferred from mutant phenotype PubMed 11331878. Source: MGI

female courtship behavior

Inferred from mutant phenotype PubMed 17676034. Source: MGI

inter-male aggressive behavior

Inferred from mutant phenotype PubMed 11823606. Source: MGI

mating behavior, sex discrimination

Inferred from mutant phenotype PubMed 11823606PubMed 11972034. Source: MGI

negative regulation of male mating behavior

Inferred from genetic interaction PubMed 24089208. Source: MGI

positive regulation of cytosolic calcium ion concentration

Inferred from physical interaction PubMed 10051594. Source: MGI

response to pheromone

Inferred from mutant phenotype PubMed 11823606PubMed 11972034PubMed 24089208. Source: MGI

territorial aggressive behavior

Inferred from mutant phenotype PubMed 11972034PubMed 17676034. Source: MGI

   Cellular_componentGolgi membrane

Inferred from direct assay PubMed 10998353. Source: MGI

dendrite membrane

Inferred from mutant phenotype PubMed 14642279. Source: MGI

endomembrane system

Inferred from direct assay PubMed 10998353. Source: MGI

endoplasmic reticulum membrane

Inferred from direct assay PubMed 10998353. Source: MGI

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

nuclear envelope

Inferred from direct assay PubMed 10998353. Source: MGI

plasma membrane

Inferred from direct assay PubMed 14699131. Source: MGI

   Molecular_functioncalmodulin binding

Inferred from direct assay PubMed 12601176. Source: MGI

diacylglycerol binding

Inferred from mutant phenotype PubMed 14642279. Source: MGI

store-operated calcium channel activity

Inferred from direct assay PubMed 10051594. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAC52700.1
Non-terminal residue1051 EMBL AAC52700.1

Sequences

Sequence LengthMass (Da)Tools
Q61057 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: B6176F90E086A253

FASTA10512,283
        10         20         30         40         50         60 
DDMIRFMFIL MIILTAFLCG LNNIYVPYQE SEKLGNFNET FQFLFWTMFG MEEHTVVDMP 

        70         80         90        100 
QFLVPEFVGR AMYGIFTIVM VIVLLNMLIA MITNSFQKIE DDADV 

« Hide

References

[1]"trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry."
Zhu X., Jiang M., Peyton M., Boulay G., Hurst R., Stefani E., Birnbaumer L.
Cell 85:661-671(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U40981 mRNA. Translation: AAC52700.1.
UniGeneMm.292904.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:109527. Trpc2.

Phylogenomic databases

InParanoidQ61057.

Gene expression databases

BgeeQ61057.
GenevestigatorQ61057.

Family and domain databases

InterProIPR005821. Ion_trans_dom.
IPR005458. TRPC2_channel.
IPR002153. TRPC_channel.
[Graphical view]
PANTHERPTHR10117. PTHR10117. 1 hit.
PTHR10117:SF6. PTHR10117:SF6. 1 hit.
PfamPF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSPR01097. TRNSRECEPTRP.
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ61057_MOUSE
AccessionPrimary (citable) accession number: Q61057
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)