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Q61017 (GBGT2_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
Alternative name(s):
G gamma-C
G-gamma-8
Gene names
Name:Gngt2
Synonyms:Gng8, Gngt8
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length69 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Subunit structure

G proteins are composed of 3 units, alpha, beta and gamma.

Subcellular location

Cell membrane; Lipid-anchor; Cytoplasmic side Potential.

Sequence similarities

Belongs to the G protein gamma family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6666Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
PRO_0000012647
Propeptide67 – 693Removed in mature form By similarity
PRO_0000012648

Amino acid modifications

Modified residue661Cysteine methyl ester By similarity
Lipidation661S-farnesyl cysteine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q61017 [UniParc].

Last modified September 27, 2004. Version 2.
Checksum: 80A9586CD56BB304

FASTA697,802
        10         20         30         40         50         60 
MAQDLSEKEL LRMEVEQLKK EVKNPRDLIS KTGKEIKDYV EAQAGTDPLL KGIPEDKNPF 


KEKGTCVLS 

« Hide

References

« Hide 'large scale' references
[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
[2]"G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development."
Williams C.J., Schultz R.M., Kopf G.S.
Mol. Reprod. Dev. 44:315-323(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 20-54.
Strain: CF-1 / Harlan.
Tissue: Retina.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK010554 mRNA. Translation: BAB27023.1.
U38500 mRNA. Translation: AAB01731.1.
CCDSCCDS25284.1.
RefSeqNP_001033753.2. NM_001038664.2.
NP_001271322.1. NM_001284393.1.
NP_001271326.1. NM_001284397.1.
NP_075610.1. NM_023121.2.
XP_006532293.1. XM_006532230.1.
XP_006532294.1. XM_006532231.1.
UniGeneMm.46299.

3D structure databases

ProteinModelPortalQ61017.
SMRQ61017. Positions 5-62.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

MaxQBQ61017.
PRIDEQ61017.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000036088; ENSMUSP00000047586; ENSMUSG00000038811.
ENSMUST00000100532; ENSMUSP00000098101; ENSMUSG00000038811.
ENSMUST00000107708; ENSMUSP00000103336; ENSMUSG00000038811.
ENSMUST00000107709; ENSMUSP00000103337; ENSMUSG00000038811.
ENSMUST00000107711; ENSMUSP00000103339; ENSMUSG00000038811.
ENSMUST00000107712; ENSMUSP00000103340; ENSMUSG00000038811.
ENSMUST00000107714; ENSMUSP00000103342; ENSMUSG00000038811.
GeneID14710.
KEGGmmu:14710.
UCSCuc007lau.1. mouse.

Organism-specific databases

CTD2793.
MGIMGI:893584. Gngt2.

Phylogenomic databases

eggNOGNOG304504.
GeneTreeENSGT00530000063397.
HOGENOMHOG000231034.
HOVERGENHBG014983.
InParanoidQ61017.
KOK04549.
OMAMISKTGK.
OrthoDBEOG7H1JP7.
PhylomeDBQ61017.
TreeFamTF319909.

Enzyme and pathway databases

ReactomeREACT_188257. Signal Transduction.

Gene expression databases

ArrayExpressQ61017.
BgeeQ61017.
GenevestigatorQ61017.

Family and domain databases

Gene3D4.10.260.10. 1 hit.
InterProIPR015898. G-protein_gamma-like_dom.
IPR001770. Gprotein-gamma.
[Graphical view]
PANTHERPTHR13809. PTHR13809. 1 hit.
PfamPF00631. G-gamma. 1 hit.
[Graphical view]
PRINTSPR00321. GPROTEING.
SMARTSM00224. GGL. 1 hit.
[Graphical view]
SUPFAMSSF48670. SSF48670. 1 hit.
PROSITEPS50058. G_PROTEIN_GAMMA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio286705.
PROQ61017.
SOURCESearch...

Entry information

Entry nameGBGT2_MOUSE
AccessionPrimary (citable) accession number: Q61017
Secondary accession number(s): Q9CWL5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: September 27, 2004
Last modified: July 9, 2014
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot