Reviewed,
UniProtKB/Swiss-Prot Q60Y65 (HPPD_CAEBR)
Last modified
November 25, 2008.
Version 29.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: 4-hydroxyphenylpyruvate dioxygenase EC=1.13.11.27 Alternative name(s): 4-hydroxyphenylpyruvic acid oxidase Short name=HPPDase Short name=4HPPD Short name=HPD | ||||
| Gene names |
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| Organism | Caenorhabditis briggsae [Complete proteome] | ||||
| Taxonomic identifier | 6238 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Protein attributes
| Sequence length | 393 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 4-hydroxyphenylpyruvate + O(2) = homogentisate + CO(2). |
| Cofactor | Binds 1 iron ion per subunit By similarity. |
| Pathway | |
| Sequence similarities | Belongs to the 4HPPD family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Phenylalanine catabolism Tyrosine catabolism |
| Ligand | Iron Metal-binding |
| Molecular function | Dioxygenase Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | L-phenylalanine catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW tyrosine catabolic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | 4-hydroxyphenylpyruvate dioxygenase activity Inferred from electronic annotation. Source: InterPro iron ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics." Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N., Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P., Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W., Hillier L.W. Waterston R.H.PLoS Biol. 1:166-192(2003) [PubMed: 14624247] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AF16. |
Cross-references
Sequence databases | |
|---|---|
| CAAC02000548 Genomic DNA. Translation: CAP35833.1. | |
3D structure databases | |
| SMR | Q60Y65. Positions 7-367. |
| ModBase | Search... |
Organism-specific databases | |
| WormBase | WBGene00037803. Cbr-hpd-1. |
Family and domain databases | |
| InterPro | IPR005956. 4OHPhenylPyrv_dOase. IPR004360. Glyas_bleo-R_dOase. [Graphical view] |
| PANTHER | PTHR11959. HPP_dOase. 1 hit. |
| Pfam | PF00903. Glyoxalase. 2 hits. [Graphical view] |
| PIRSF | PIRSF009283. HPP_dOase. 1 hit. |
| TIGRFAMs | TIGR01263. 4HPPD. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | HPPD_CAEBR | ||||||||
| Accession | Primary (citable) accession number: Q60Y65 Secondary accession number(s): A8XSJ1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Caenorhabditis annotation project | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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