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Protein
Submitted name:

SRY-box containing gene 2

Gene

Sox2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi43 – 111HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-3769402 Deactivation of the beta-catenin transactivating complex

Names & Taxonomyi

Protein namesi
Submitted name:
SRY-box containing gene 2Imported
Submitted name:
Sox2 proteinImported
Submitted name:
Transcription factor SOX-2Imported
Submitted name:
Transcriptional factor SOX2Imported
Gene namesi
Name:Sox2Imported
ORF Names:mCG_15247Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:98364 Sox2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000074637

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ60I23, 49 interactors

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 111HMG boxInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiENOG410IPZI Eukaryota
ENOG411009V LUCA
GeneTreeiENSGT00760000118988
HOVERGENiHBG105663
KOiK16796
OMAiQSYMNGS
OrthoDBiEOG091G0F15
TreeFamiTF351735

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR032643 SOX-2
IPR022097 SOX_fam
PANTHERiPTHR10270:SF231 PTHR10270:SF231, 1 hit
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
PF12336 SOXp, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q60I23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYNMMETELK PPGPQQASGG GGGGGNATAA ATGGNQKNSP DRVKRPMNAF
60 70 80 90 100
MVWSRGQRRK MAQENPKMHN SEISKRLGAE WKLLSETEKR PFIDEAKRLR
110 120 130 140 150
ALHMKEHPDY KYRPRRKTKT LMKKDKYTLP GGLLAPGGNS MASGVGVGAG
160 170 180 190 200
LGAGVNQRMD SYAHMNGWSN GSYSMMQEQL GYPQHPGLNA HGAAQMQPMH
210 220 230 240 250
RYDVSALQYN SMTSSQTYMN GSPTYSMSYS QQGTPGMALG SMGSVVKSEA
260 270 280 290 300
SSSPPVVTSS SHSRAPCQAG DLRDMISMYL PGAEVPEPAA PSRLHMAQHY
310
QSGPVPGTAI NGTLPLSHM
Length:319
Mass (Da):34,406
Last modified:May 10, 2005 - v1
Checksum:i07A6DFDCA205991F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606746 Genomic DNA No translation available.
BC057574 mRNA Translation: AAH57574.1
AB108673 mRNA Translation: BAC75668.1
CH466530 Genomic DNA Translation: EDL35051.1
RefSeqiNP_035573.3, NM_011443.4
UniGeneiMm.65396

Genome annotation databases

EnsembliENSMUST00000099151; ENSMUSP00000096755; ENSMUSG00000074637
GeneIDi20674
KEGGimmu:20674
UCSCiuc008oxu.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ60I23_MOUSE
AccessioniPrimary (citable) accession number: Q60I23
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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