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Protein
Submitted name:

Glutathione S-transferase

Gene

gst

Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei10 – 101Glutathione; via amide nitrogenCombined sources
Binding sitei35 – 351GlutathioneCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione S-transferaseImported (EC:2.5.1.18Imported)
Gene namesi
Name:gstImported
Ordered Locus Names:MCA0074Imported
OrganismiMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)Imported
Taxonomic identifieri243233 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus
Proteomesi
  • UP000006821 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243233.MCA0074.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UAPX-ray2.80A1-203[»]
3UARX-ray2.60A1-203[»]
ProteinModelPortaliQ60CN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 8181GST N-terminalInterPro annotationAdd
BLAST
Domaini87 – 203117GST C-terminalInterPro annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni51 – 522Glutathione bindingCombined sources
Regioni65 – 662Glutathione bindingCombined sources
Regioni103 – 1042Glutathione bindingCombined sources

Sequence similaritiesi

Belongs to the GST superfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108K3A. Bacteria.
COG0625. LUCA.
HOGENOMiHOG000125748.
KOiK00799.
OMAiSHKLQDG.
OrthoDBiEOG6H1Q01.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q60CN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLYYFPGAC SLAPHIVLRE AGLDFELENV DLGTKKTGSG ADFLQVNPKG
60 70 80 90 100
YVPALQLDDG QVLTEDQVIL QYLADLKPES GLMPPSGTFE RYRLLEWLAF
110 120 130 140 150
ISTEIHKTFG PFWNPESPEA SKQIALGLLS RRLDYVEDRL EAGGPWLMGD
160 170 180 190 200
RYSVADAYLS TVLGWCEYLK IDLSKWPRIL AYLERNQARP AVQAAMKAEG

LIQ
Length:203
Mass (Da):22,799
Last modified:November 23, 2004 - v1
Checksum:iBA1E8FB1F70EB672
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017282 Genomic DNA. Translation: AAU90767.1.
RefSeqiWP_010959446.1. NC_002977.6.

Genome annotation databases

EnsemblBacteriaiAAU90767; AAU90767; MCA0074.
KEGGimca:MCA0074.
PATRICi22603871. VBIMetCap22254_0079.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017282 Genomic DNA. Translation: AAU90767.1.
RefSeqiWP_010959446.1. NC_002977.6.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UAPX-ray2.80A1-203[»]
3UARX-ray2.60A1-203[»]
ProteinModelPortaliQ60CN1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243233.MCA0074.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU90767; AAU90767; MCA0074.
KEGGimca:MCA0074.
PATRICi22603871. VBIMetCap22254_0079.

Phylogenomic databases

eggNOGiENOG4108K3A. Bacteria.
COG0625. LUCA.
HOGENOMiHOG000125748.
KOiK00799.
OMAiSHKLQDG.
OrthoDBiEOG6H1Q01.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33009 / NCIMB 11132 / BathImported.
  2. "Crystal Structure of Glutathione S-Transferase from Methylococcus Capsulatus."
    Patskovsky Y., Toro R., Bhosle R., Zencheck W.D., Hillerich B., Seidel R.D., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Imker H.J., Armstrong R.N., Gerlt J.A., Almo S.C.
    Submitted (OCT-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS), X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) IN COMPLEX WITH GLUTATHIONE.

Entry informationi

Entry nameiQ60CN1_METCA
AccessioniPrimary (citable) accession number: Q60CN1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: March 16, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.