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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciMCAP243233:G1G0X-160-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:MCA0159
OrganismiMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Taxonomic identifieri243233 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus
Proteomesi
  • UP000006821 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120691 – 278Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST278

Proteomic databases

PRIDEiQ60CE9

Interactioni

Protein-protein interaction databases

STRINGi243233.MCA0159

Structurei

3D structure databases

ProteinModelPortaliQ60CE9
SMRiQ60CE9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q60CE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIYAIGDVQ GCYAELRRLL ELIRFDPAKD RLLFTGDLVN RGPQSLETLR
60 70 80 90 100
FIRGLGPAAA TVLGNHDLHL LAVACGVSRV KHKDTFGDVL EAADRDELLA
110 120 130 140 150
WLRTRPLVHR EGSYCLVHAG IPPAWNAETA MARAGEVETV LAAGDITGFC
160 170 180 190 200
RQMYGDKPDL WSDDLAGWDR LRFITNALTR MRYCDRTGRL DFRQKGAPGR
210 220 230 240 250
QPASLVPWFD VPDRVPPGAT IVFGHWSTLG YFAGKDCYCL DTGCLWGGEL
260 270
TALKLDGTLE RYAVPSLHGG YQKPTLAK
Length:278
Mass (Da):30,717
Last modified:November 23, 2004 - v1
Checksum:iBA3A992BBAF4B2CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017282 Genomic DNA Translation: AAU90598.1
RefSeqiWP_010959527.1, NC_002977.6

Genome annotation databases

EnsemblBacteriaiAAU90598; AAU90598; MCA0159
KEGGimca:MCA0159

Similar proteinsi

Entry informationi

Entry nameiAPAH_METCA
AccessioniPrimary (citable) accession number: Q60CE9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 23, 2004
Last modified: May 23, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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