Reviewed, UniProtKB/Swiss-Prot Q60BB2 (GLND_METCA)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	MCA0565

Organism

Methylococcus capsulatus [Complete proteome] [HAMAP]

Taxonomic identifier

414 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Methylococcales › Methylococcaceae › Methylococcus

Protein attributes

Sequence length	877 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity.
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Biological process	Nitrogen fixation
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen fixation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 877	877	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_0000192744

Sequences

	Sequence		Length	Mass (Da)
	Q60BB2-1 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 54954C07DB9E3AE9	FASTA	877	99,886
	10 20 30 40 50 60 MDGPNSDRAH DRHAFDRVAA CKARIQHNTA ELAERFRTGT PVADLIRERT AFIDHLLSEA 70 80 90 100 110 120 WDRRIGRGAT DVALVAVGGY GRGELLLHSD VDLLILLDEA APSSRKQDLS DFLRLLWDIG 130 140 150 160 170 180 LKPGHSVRSP AECAEAARTD QTIITNLLEG RLLVGSAALW EAVRSETAPE RMWSSAAFFE 190 200 210 220 230 240 AKMAEQRIRY SKYHNTAYNL EPNVKEGPGG LRDIQLIGWI IRRHSDARGL QDLVAHGWLT 250 260 270 280 290 300 DAEYRELKEA QAFLWRIRFA LHALTGRCED RLLFDYQREL AGLFGYRGET SNEVVEGFMQ 310 320 330 340 350 360 DYFRTVTGVE RLNELLLQLF NEAVLHRDDA FSPTPVNDHF QAVNDYLEAV HPAVFREHPL 370 380 390 400 410 420 ALLEVFLILQ KNSALEGVRA ATIRLIRQHI HLIDDAFRND PEACRLFMDI LRQPGGVTHQ 430 440 450 460 470 480 LRRMNRYGVL AAYLPEFGRV VGRMQYDLFH VYTVDEHTLF VVRNLRRFAL EEFQQENPLC 490 500 510 520 530 540 YELFQLIEKP ELLYIAALMH DIAKGSDGDH SEVGERIAEE FCRRHRIGPR ETLLVKWLVR 550 560 570 580 590 600 HHLVMSMTAQ RKDLSDPEVI HEFAQIVRNQ NTLNHLYLLT VADIRATNPS LWNSWKGALL 610 620 630 640 650 660 QELYTSTSWT LRRGLDTPPD YAEQISAAKD EARTLLQRFG LAEDAITAVW ENIGDDYFLR 670 680 690 700 710 720 FLPEEIAWHT TAIAACRPEH LPLVLLRPES LRGSVEVFIY ERNRDFLFAQ TTAVLDQLGL 730 740 750 760 770 780 TVLDAKIIAS RQGFALLSFN VLERSGTAPE GLFRLVQICD RLKEALSGGG APPPAVSRLA 790 800 810 820 830 840 TRQIRHFTVP TKVFFHDDPQ NRFSILELIA TDRPGLLSKV GQAFMRTGIR LHNAKISTVG 850 860 870 SRAEDIFFIT DREDRPLDGE ADRAALRRVL IEFVGDQ

References

[1]

"Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath)." Ward N.L., Larsen O., Sakwa J., Bruseth L., Khouri H.M., Durkin A.S., Dimitrov G., Jiang L., Scanlan D., Kang K.H., Lewis M.R., Nelson K.E., Methe B.A., Wu M., Heidelberg J.F., Paulsen I.T., Fouts D.E., Ravel J. , Tettelin H., Ren Q., Read T.D., DeBoy R.T., Seshadri R., Salzberg S.L., Jensen H.B., Birkeland N.K., Nelson W.C., Dodson R.J., Grindhaug S.H., Holt I.E., Eidhammer I., Jonasen I., Vanaken S., Utterback T.R., Feldblyum T.V., Fraser C.M., Lillehaug J.R., Eisen J.A. PLoS Biol. 2:1616-1628(2004) [PubMed: 15383840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bath / NCIMB 11132.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017282 Genomic DNA. Translation: AAU93245.1.
RefSeq	YP_113084.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3103204.
GenomeReviews	Gene locus MCA0565 in contig AE017282_GR.
KEGG	mca:MCA0565.
NMPDR	fig|243233.4.peg.1115.
TIGR	MCA0565.
Phylogenomic databases
HOGENOM	Q60BB2.
OMA	MQHDLFH.
Enzyme and pathway databases
BioCyc	MCAP243233:MCA_0565-MON.
BRENDA	2.7.7.59. 2172.
Family and domain databases
HAMAP	MF_00277. [Tree]
InterPro	IPR002912. ACT_bd. IPR010043. GlnD_Uridyltrans. IPR003607. Met-dep_phosphohydro_HD. IPR006674. Met-dep_phosphohydro_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_METCA

Accession

Primary (citable) accession number: Q60BB2

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2005
Last sequence update:	November 23, 2004
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)