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Q609I7

- G6PI_METCA

UniProt

Q609I7 - G6PI_METCA

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei353 – 3531Proton donorUniRule annotation
Active sitei384 – 3841UniRule annotation
Active sitei512 – 5121UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:MCA1247
OrganismiMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Taxonomic identifieri243233 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus
ProteomesiUP000006821: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 546546Glucose-6-phosphate isomerasePRO_0000180672Add
BLAST

Proteomic databases

PRIDEiQ609I7.

Interactioni

Protein-protein interaction databases

STRINGi243233.MCA1247.

Structurei

3D structure databases

ProteinModelPortaliQ609I7.
SMRiQ609I7. Positions 4-546.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiRAHYVSN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q609I7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPQSTDLPAW RTLSEHFKTI APRHMRDMFA DDPGRFEAFS VRLGDLLFDY
60 70 80 90 100
SKNRITRETV ATLIQLAEEA GLREKIDAMF RGERLNVTEN RAVLHVALRN
110 120 130 140 150
RSNRPIRVDG KDVMPEVNRV LDRMRRFSQS VRTGEWRGAT GKAITDVVNI
160 170 180 190 200
GIGGSDLGPK MVVKALQPYA DPRLRAHFVS NVDESDLVEI LRPLNPETTL
210 220 230 240 250
FVVASKTFTT QETMTNGRSA RAWFLERISD ESAIARHFVA ISTNRNKVAE
260 270 280 290 300
FGIDPRNMFE FWDWVGGRYS LWSAIGLPIA LSVGMDRFEE LLEGAHFVDE
310 320 330 340 350
HFRTAPFERN IPVLMGLLGI WYINFFGAQS HAVLPYDQYL EDLPAHLQQA
360 370 380 390 400
DMESNGKTVD VEGRPVNYST GPVIFGQPGT NGQHAFYQLL HQGSMLVPCD
410 420 430 440 450
FLAAAESHHP LAEHHDILIS NFLAQTEALM RGRTTDEARQ EIASEELPPE
460 470 480 490 500
RLEALAAAKT FPGNKPTNSF LYRRLDPHTL GMLIALYEHK IFTQGVIWYI
510 520 530 540
NSFDQMGVEL GKQLAKTILA ELPGDAPVAS HDASTNGLIR YFKSLR
Length:546
Mass (Da):61,530
Last modified:November 23, 2004 - v1
Checksum:i6944A9E2C776464C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017282 Genomic DNA. Translation: AAU92469.1.
RefSeqiWP_010960530.1. NC_002977.6.
YP_113710.1. NC_002977.6.

Genome annotation databases

EnsemblBacteriaiAAU92469; AAU92469; MCA1247.
GeneIDi3104273.
KEGGimca:MCA1247.
PATRICi22606330. VBIMetCap22254_1279.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017282 Genomic DNA. Translation: AAU92469.1 .
RefSeqi WP_010960530.1. NC_002977.6.
YP_113710.1. NC_002977.6.

3D structure databases

ProteinModelPortali Q609I7.
SMRi Q609I7. Positions 4-546.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243233.MCA1247.

Proteomic databases

PRIDEi Q609I7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU92469 ; AAU92469 ; MCA1247 .
GeneIDi 3104273.
KEGGi mca:MCA1247.
PATRICi 22606330. VBIMetCap22254_1279.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi RAHYVSN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33009 / NCIMB 11132 / Bath.

Entry informationi

Entry nameiG6PI_METCA
AccessioniPrimary (citable) accession number: Q609I7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3