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Q608P2 (Q608P2_METCA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654
EC=1.3.3.11 HAMAP MF_00654
Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654
Gene names
Name:pqqC HAMAP MF_00654
Ordered Locus Names:MCA1447
OrganismMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) [Complete proteome] [HAMAP] EMBL AAU92560.1
Taxonomic identifier243233 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Methylococcales › Methylococcaceae › Methylococcus

Protein attributes

Sequence length241 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Keywords
   Biological processPQQ biosynthesis HAMAP MF_00654
   Molecular functionOxidoreductase HAMAP MF_00654
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q608P2 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 20E18655AA5D2DAF

FASTA24128,194
        10         20         30         40         50         60 
MSQDTIPWSR EEFEARLRAK EKYYHIHHPY HVLMASGELN REQIQGWVAN RFYYQITIPR 

        70         80         90        100        110        120 
KDSAIMANCP DRETRRKWMQ RVMDHDGYGD DPGGIEAWIQ LGIACGLSRE DITSLRHVLP 

       130        140        150        160        170        180 
GVRFAVDAYL NFARTATWQE AACSSLTELF APTIHKQRLA GWPDLYPWIA ADGLAYFRKR 

       190        200        210        220        230        240 
VTQASRDVEH GIEITLDHFK TREQQERALE ILQFKLDILW SMLDAMYLAY VDKKPPYFNI 


A

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017282 Genomic DNA. Translation: AAU92560.1.
RefSeqYP_113905.1. NC_002977.6.

3D structure databases

ProteinModelPortalQ608P2.
SMRQ608P2. Positions 9-240.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3103081.
GenomeReviewsGene locus MCA1447 in contig AE017282_GR.
KEGGmca:MCA1447.
NMPDRfig|243233.4.peg.884.
PATRIC22606730. VBIMetCap22254_1477.
TIGRMCA1447.

Phylogenomic databases

HOGENOMHBG288944.
OMADSWPQHY.
ProtClustDBPRK05157.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synthPqqC_dom.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KOK06137.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ608P2_METCA
AccessionPrimary (citable) accession number: Q608P2
Entry history
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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